JP3825051B2 - 吸入装置 - Google Patents

吸入装置 Download PDF

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Publication number
JP3825051B2
JP3825051B2 JP51334497A JP51334497A JP3825051B2 JP 3825051 B2 JP3825051 B2 JP 3825051B2 JP 51334497 A JP51334497 A JP 51334497A JP 51334497 A JP51334497 A JP 51334497A JP 3825051 B2 JP3825051 B2 JP 3825051B2
Authority
JP
Japan
Prior art keywords
chamber
inhaler
dispersion
dispersion chamber
piston
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP51334497A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11511372A5 (https=
JPH11511372A (ja
Inventor
バリィ,エルナ
イェップソン,マグヌス
マキャンドリュー,ジョン・エイ
レベル,ウィリアム・ジェイ
ロバートソン,ポール・エイ
Original Assignee
アストラ・アクチエボラーグ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アストラ・アクチエボラーグ filed Critical アストラ・アクチエボラーグ
Publication of JPH11511372A publication Critical patent/JPH11511372A/ja
Publication of JPH11511372A5 publication Critical patent/JPH11511372A5/ja
Application granted granted Critical
Publication of JP3825051B2 publication Critical patent/JP3825051B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0013Details of inhalators; Constructional features thereof with inhalation check valves
    • A61M15/0016Details of inhalators; Constructional features thereof with inhalation check valves located downstream of the dispenser, i.e. traversed by the product
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • A61M15/0023Mouthpieces therefor retractable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • A61M15/0088Inhalation chambers with variable volume
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/07General characteristics of the apparatus having air pumping means
    • A61M2205/071General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073Syringe, piston type

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Nozzles (AREA)
  • External Artificial Organs (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP51334497A 1995-09-27 1996-09-23 吸入装置 Expired - Lifetime JP3825051B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9503344A SE9503344D0 (sv) 1995-09-27 1995-09-27 Inhalation device
SE9503344-5 1995-09-27
PCT/SE1996/001184 WO1997011732A1 (en) 1995-09-27 1996-09-23 Inhalation device

Publications (3)

Publication Number Publication Date
JPH11511372A JPH11511372A (ja) 1999-10-05
JPH11511372A5 JPH11511372A5 (https=) 2004-09-30
JP3825051B2 true JP3825051B2 (ja) 2006-09-20

Family

ID=20399612

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51334497A Expired - Lifetime JP3825051B2 (ja) 1995-09-27 1996-09-23 吸入装置

Country Status (28)

Country Link
US (1) US6286506B1 (https=)
EP (1) EP0852508B1 (https=)
JP (1) JP3825051B2 (https=)
CN (1) CN1202117A (https=)
AR (1) AR003595A1 (https=)
AT (1) ATE228867T1 (https=)
AU (1) AU714995B2 (https=)
BR (1) BR9610693A (https=)
CA (1) CA2232453A1 (https=)
CZ (1) CZ92898A3 (https=)
DE (1) DE69625219T2 (https=)
EE (1) EE9800094A (https=)
EG (1) EG20990A (https=)
HU (1) HUP9802347A3 (https=)
IL (1) IL123612A0 (https=)
IS (1) IS4698A (https=)
MY (1) MY132402A (https=)
NO (1) NO981325L (https=)
NZ (1) NZ318915A (https=)
PL (1) PL325826A1 (https=)
RU (1) RU2181058C2 (https=)
SE (1) SE9503344D0 (https=)
SG (2) SG90046A1 (https=)
SK (1) SK39398A3 (https=)
TR (2) TR199900011T2 (https=)
TW (1) TW343925B (https=)
WO (1) WO1997011732A1 (https=)
ZA (1) ZA967805B (https=)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9503344D0 (sv) 1995-09-27 1995-09-27 Astra Ab Inhalation device
SE9700935D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Inhalation device
US6192876B1 (en) 1997-12-12 2001-02-27 Astra Aktiebolag Inhalation apparatus and method
RO121834B1 (ro) * 1998-03-16 2008-06-30 Inhale Therapeutic Systems, Inc. Dispozitiv pentru administrarea unui agent activ
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
SE0000935D0 (sv) * 2000-03-21 2000-03-21 Astrazeneca Ab An inhalation device
US6705316B2 (en) 2002-03-11 2004-03-16 Battelle Pulmonary Therapeutics, Inc. Pulmonary dosing system and method
US6923175B2 (en) 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
MX373000B (es) 2005-09-14 2020-05-21 Mannkind Corp Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas.
DE102006007495A1 (de) 2006-02-17 2007-08-23 Siegfried Generics International Ag Dispergiereinheit
EP1986679B1 (en) 2006-02-22 2017-10-25 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
GB2479843B (en) 2007-05-18 2012-02-29 Malvern Instr Ltd Method and apparatus for dispersing a sample of particulate material
JP5570996B2 (ja) 2007-12-14 2014-08-13 エアロデザインズ インコーポレイテッド エアロゾル化可能な食料品の送達
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN101827626B (zh) 2008-06-13 2015-03-18 曼金德公司 干粉吸入器和用于药物输送的系统
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
KR102584844B1 (ko) 2009-06-12 2023-10-04 맨카인드 코포레이션 한정된 비표면적을 갖는 디케토피페라진 마이크로입자
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
CN102985125A (zh) 2010-06-21 2013-03-20 曼金德公司 干粉药物输送系统和方法
SG194034A1 (en) 2011-04-01 2013-11-29 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
MX2014004983A (es) 2011-10-24 2014-09-22 Mannkid Corp Metodos y composiciones para tratar dolor.
KR102264177B1 (ko) 2012-07-12 2021-06-11 맨카인드 코포레이션 건조 분말 약물 전달 시스템 및 방법
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
EP3345643B1 (en) 2013-03-15 2021-01-06 Chris V. Ciancone Inhaler spacer and storage apparatus
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
MX375448B (es) 2013-07-18 2025-03-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
EP3693044A1 (en) 2019-02-07 2020-08-12 Koninklijke Philips N.V. Breath actuated inhalers

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA699313A (en) * 1964-12-08 G. Cheney Ralph Atomizer
US523992A (en) * 1894-08-07 End post for wire fences
US3636949A (en) * 1969-08-08 1972-01-25 Armstrong Kropp Dev Corp Inhalation-initiated aerosol dispenser
SE411705B (sv) 1976-11-09 1980-02-04 Draco Ab Anordning for generering av en avskermad, vesentligen drivmedelsfri aerosol
DE3274065D1 (de) 1981-07-08 1986-12-11 Draco Ab Powder inhalator
DE3429389C1 (de) * 1984-08-09 1986-03-13 Brugger, Inge, geb. Ritzau, 8130 Starnberg Inhalator
SE453566B (sv) 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
IT1217890B (it) * 1988-06-22 1990-03-30 Chiesi Farma Spa Dispositivo per l'inalazione di aerosol dosati
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
DE4027749A1 (de) * 1990-09-01 1992-03-05 Pfeiffer Erich Gmbh & Co Kg Austragvorrichtung fuer medien
SE9002895D0 (sv) 1990-09-12 1990-09-12 Astra Ab Inhalation devices for dispensing powders i
EP0548152B1 (en) * 1990-09-12 1996-07-24 BISGAARD, Hans An inhaling device
FR2676929B1 (fr) * 1991-05-30 1994-02-11 Aerosols Bouchage Ste Fse Inhalateur de poudres.
US5341801A (en) * 1991-12-03 1994-08-30 Sandoz Ltd. Inhaler
DE4237568C1 (de) * 1992-11-06 1994-05-11 Dieter Dipl Ing Dr Med Koehler Verfahren und Vorrichtung zum Erzeugen eines Aerosols
DE4239402A1 (de) 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
SE9404439D0 (sv) 1994-12-21 1994-12-21 Astra Ab Inhalation device
US5823183A (en) * 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
SE9503344D0 (sv) 1995-09-27 1995-09-27 Astra Ab Inhalation device

Also Published As

Publication number Publication date
CZ92898A3 (cs) 1998-10-14
MX9802214A (es) 1998-08-30
RU2181058C2 (ru) 2002-04-10
EP0852508B1 (en) 2002-12-04
BR9610693A (pt) 1999-07-06
AU7102596A (en) 1997-04-17
NZ318915A (en) 1999-11-29
EP0852508A1 (en) 1998-07-15
ATE228867T1 (de) 2002-12-15
TR199800570T2 (xx) 1998-07-21
AU714995B2 (en) 2000-01-13
TW343925B (en) 1998-11-01
PL325826A1 (en) 1998-08-03
TR199900011T2 (xx) 1999-08-23
HUP9802347A2 (hu) 1999-01-28
NO981325L (no) 1998-05-26
SG90046A1 (en) 2002-07-23
CA2232453A1 (en) 1997-04-03
DE69625219T2 (de) 2003-08-28
NO981325D0 (no) 1998-03-24
SG90045A1 (en) 2002-07-23
EE9800094A (et) 1998-10-15
HUP9802347A3 (en) 1999-04-28
US6286506B1 (en) 2001-09-11
MY132402A (en) 2007-10-31
IL123612A0 (en) 1998-10-30
CN1202117A (zh) 1998-12-16
ZA967805B (en) 1997-03-27
DE69625219D1 (de) 2003-01-16
AR003595A1 (es) 1998-08-05
WO1997011732A1 (en) 1997-04-03
SE9503344D0 (sv) 1995-09-27
IS4698A (is) 1998-03-24
SK39398A3 (en) 1998-09-09
JPH11511372A (ja) 1999-10-05
EG20990A (en) 2000-08-30

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