JP3296434B2 - 保護されたアミノ酸構成単位、生産と使用 - Google Patents

保護されたアミノ酸構成単位、生産と使用

Info

Publication number
JP3296434B2
JP3296434B2 JP51124692A JP51124692A JP3296434B2 JP 3296434 B2 JP3296434 B2 JP 3296434B2 JP 51124692 A JP51124692 A JP 51124692A JP 51124692 A JP51124692 A JP 51124692A JP 3296434 B2 JP3296434 B2 JP 3296434B2
Authority
JP
Japan
Prior art keywords
amino acid
unit
amino
hydrogen atom
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP51124692A
Other languages
English (en)
Japanese (ja)
Other versions
JPH07501312A (ja
Inventor
バルトル，ラルフ
フランク，ロナルド
Original Assignee
ゲゼルシャフト・フュア・ビオテクノロギッシェ・フォルシュンク・ミット・ベシュレンクテル・ハフツング （ゲー・ベー・エフ）
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ゲゼルシャフト・フュア・ビオテクノロギッシェ・フォルシュンク・ミット・ベシュレンクテル・ハフツング （ゲー・ベー・エフ） filed Critical ゲゼルシャフト・フュア・ビオテクノロギッシェ・フォルシュンク・ミット・ベシュレンクテル・ハフツング （ゲー・ベー・エフ）
Publication of JPH07501312A publication Critical patent/JPH07501312A/ja
Application granted granted Critical
Publication of JP3296434B2 publication Critical patent/JP3296434B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP51124692A 1991-06-13 1992-06-05 保護されたアミノ酸構成単位、生産と使用 Expired - Fee Related JP3296434B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19914119544 DE4119544C1 (enExample) 1991-06-13 1991-06-13
DE4119544.2 1991-06-13
PCT/EP1992/001280 WO1992022566A1 (de) 1991-06-13 1992-06-05 Geschützter aminosäurebaustein, herstellung und verwendung

Publications (2)

Publication Number Publication Date
JPH07501312A JPH07501312A (ja) 1995-02-09
JP3296434B2 true JP3296434B2 (ja) 2002-07-02

Family

ID=6433885

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51124692A Expired - Fee Related JP3296434B2 (ja) 1991-06-13 1992-06-05 保護されたアミノ酸構成単位、生産と使用

Country Status (4)

Country Link
EP (1) EP0589927A1 (enExample)
JP (1) JP3296434B2 (enExample)
DE (1) DE4119544C1 (enExample)
WO (1) WO1992022566A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117974A (en) * 1991-10-02 2000-09-12 Peptor Limited Libraries of backbone-cyclized peptidomimetics
US6407059B1 (en) 1994-06-08 2002-06-18 Peptor Limited Conformationally constrained backbone cyclized peptide analogs
AU724386B2 (en) * 1994-06-08 2000-09-21 Peptor Ltd Conformationally constrained backbone cyclized peptide analogs
IL109943A (en) * 1994-06-08 2006-08-01 Develogen Israel Ltd Conformationally constrained backbone cyclized peptide analogs
DE4431513A1 (de) * 1994-09-03 1996-03-07 Carsten Goldammer Racemisierungsfreie Herstellung und Verwendung von N-Methoxy- oder -Hydroxy-benzyl-Aminosäurederivaten und -Dipeptiden
US5770687A (en) * 1995-06-07 1998-06-23 Peptor Limited Comformationally constrained backbone cyclized somatostatin analogs
US6051554A (en) * 1995-06-07 2000-04-18 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
US6841533B1 (en) 1995-12-07 2005-01-11 Peptor Limited Conformationally constrained backbone cyclized interleukin-6 antagonists
US6355613B1 (en) 1996-07-31 2002-03-12 Peptor Limited Conformationally constrained backbone cyclized somatostatin analogs
WO2011140393A1 (en) 2010-05-05 2011-11-10 Prolynx Llc Controlled release from macromolecular conjugates
WO2023219152A1 (ja) * 2022-05-13 2023-11-16 中外製薬株式会社 リチウム塩の析出工程を含む、アミノ酸の塩若しくはペプチド化合物の塩又はこれらの溶媒和物の製造方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH516523A (fr) * 1969-11-25 1971-12-15 Sogespar S A Procédé de préparation des dérivés des acides a-aminés N-disubstitués par benzoylation

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Ｃｈｅｍｉｓｔｒｙ Ｌｅｔｔｅｒｓ，Ｎｏ．１１（１９８９），ｐ．１９６３−１９６６
Ｔｅｔｒａｈｅｄｒｏｎ，Ｖｏｌ．４６，Ｎｏ．６，ｐ．１７９１−１８３７（１９９０）

Also Published As

Publication number Publication date
JPH07501312A (ja) 1995-02-09
EP0589927A1 (de) 1994-04-06
WO1992022566A1 (de) 1992-12-23
DE4119544C1 (enExample) 1992-10-15

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