JP3130048B2 - エストロゲン依存症の治療 - Google Patents

エストロゲン依存症の治療

Info

Publication number
JP3130048B2
JP3130048B2 JP07520794A JP52079495A JP3130048B2 JP 3130048 B2 JP3130048 B2 JP 3130048B2 JP 07520794 A JP07520794 A JP 07520794A JP 52079495 A JP52079495 A JP 52079495A JP 3130048 B2 JP3130048 B2 JP 3130048B2
Authority
JP
Japan
Prior art keywords
antiprogestin
drug
administration
estrogen
gonadotropin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP07520794A
Other languages
English (en)
Japanese (ja)
Other versions
JPH09508418A (ja
Inventor
ディー．ホドゲン ゲリー
エフ．ウィリアムス ロバート
グロウ ダニエル
Original Assignee
ザ メディカル カレッジ オブ ハンプトン ロード
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ザ メディカル カレッジ オブ ハンプトン ロード filed Critical ザ メディカル カレッジ オブ ハンプトン ロード
Publication of JPH09508418A publication Critical patent/JPH09508418A/ja
Application granted granted Critical
Publication of JP3130048B2 publication Critical patent/JP3130048B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP07520794A 1994-02-04 1995-02-02 エストロゲン依存症の治療 Expired - Fee Related JP3130048B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/191,631 US5681817A (en) 1994-02-04 1994-02-04 Treatment of ovarian estrogen dependent conditions
US08/191,631 1994-02-04
US191,631 1994-02-04
PCT/US1995/001479 WO1995020972A1 (en) 1994-02-04 1995-02-02 Treatment of ovarian estrogen dependent conditions

Publications (2)

Publication Number Publication Date
JPH09508418A JPH09508418A (ja) 1997-08-26
JP3130048B2 true JP3130048B2 (ja) 2001-01-31

Family

ID=22706258

Family Applications (1)

Application Number Title Priority Date Filing Date
JP07520794A Expired - Fee Related JP3130048B2 (ja) 1994-02-04 1995-02-02 エストロゲン依存症の治療

Country Status (29)

Country Link
US (1) US5681817A (show.php)
EP (1) EP0785792B1 (show.php)
JP (1) JP3130048B2 (show.php)
KR (1) KR970700507A (show.php)
CN (1) CN1144486A (show.php)
AP (1) AP724A (show.php)
AT (1) ATE179610T1 (show.php)
AU (1) AU689229B2 (show.php)
BG (1) BG62238B1 (show.php)
BR (1) BR9506606A (show.php)
CA (1) CA2182183C (show.php)
CZ (1) CZ291709B6 (show.php)
DE (1) DE69509544T2 (show.php)
DK (1) DK0785792T3 (show.php)
ES (1) ES2132645T3 (show.php)
FI (1) FI963036L (show.php)
GR (1) GR3030164T3 (show.php)
HU (1) HUT74622A (show.php)
LT (1) LT4182B (show.php)
LV (1) LV11782B (show.php)
MD (1) MD1432C2 (show.php)
NZ (1) NZ281441A (show.php)
OA (1) OA10777A (show.php)
PL (1) PL178273B1 (show.php)
RO (1) RO117420B1 (show.php)
RU (1) RU2110274C1 (show.php)
SK (1) SK96296A3 (show.php)
TJ (1) TJ242B (show.php)
WO (1) WO1995020972A1 (show.php)

Families Citing this family (41)

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WO1996003138A1 (en) * 1994-07-22 1996-02-08 The Medical College Of Hampton Roads Establishment of tonic ovarian estrogen secretion for extended therapeutic regimens
US5780435A (en) * 1995-12-15 1998-07-14 Praecis Pharmaceuticals Incorporated Methods for treating prostate cancer with LHRH-R antagonists
US6274573B1 (en) 1997-10-17 2001-08-14 Mochida Pharmaceutical Co., Ltd. Method of treatment for uterine leiomyoma
US6703367B1 (en) 1999-04-27 2004-03-09 Praecis Pharmaceuticals Inc. Methods for treating hot flashes and gynaecomastia
US6399593B1 (en) 1999-05-04 2002-06-04 Wyeth Cyclic regimens using cyclic urea and cyclic amide derivatives
US6444668B1 (en) 1999-05-04 2002-09-03 Wyeth Combination regimens using progesterone receptor modulators
US6358948B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Quinazolinone and benzoxazine derivatives as progesterone receptor modulators
US6462032B1 (en) 1999-05-04 2002-10-08 Wyeth Cyclic regimens utilizing indoline derivatives
US6329416B1 (en) 1999-05-04 2001-12-11 American Home Products Corporation Combination regimens using 3,3-substituted indoline derivatives
US6391907B1 (en) * 1999-05-04 2002-05-21 American Home Products Corporation Indoline derivatives
US6306851B1 (en) 1999-05-04 2001-10-23 American Home Products Corporation Cyclocarbamate and cyclic amide derivatives
US6407101B1 (en) 1999-05-04 2002-06-18 American Home Products Corporation Cyanopyrroles
US6380178B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Cyclic regimens using cyclocarbamate and cyclic amide derivatives
US6319912B1 (en) 1999-05-04 2001-11-20 American Home Products Corporation Cyclic regimens using 2,1-benzisothiazoline 2,2-dioxides
US6369056B1 (en) 1999-05-04 2002-04-09 American Home Products Corporation Cyclic urea and cyclic amide derivatives
US6339098B1 (en) 1999-05-04 2002-01-15 American Home Products Corporation 2,1-benzisothiazoline 2,2-dioxides
US6355648B1 (en) * 1999-05-04 2002-03-12 American Home Products Corporation Thio-oxindole derivatives
US6358947B1 (en) 1999-05-04 2002-03-19 American Home Products Corporation Tetracyclic progesterone receptor modulator compounds and methods
US6417214B1 (en) 1999-05-04 2002-07-09 Wyeth 3,3-substituted indoline derivatives
US6498154B1 (en) 1999-05-04 2002-12-24 Wyeth Cyclic regimens using quinazolinone and benzoxazine derivatives
US6423699B1 (en) 1999-05-04 2002-07-23 American Home Products Corporation Combination therapies using benzimidazolones
US6509334B1 (en) 1999-05-04 2003-01-21 American Home Products Corporation Cyclocarbamate derivatives as progesterone receptor modulators
US6380235B1 (en) 1999-05-04 2002-04-30 American Home Products Corporation Benzimidazolones and analogues
US8193252B1 (en) 1999-08-31 2012-06-05 Bayer Pharma AG Mesoprogestins (progesterone receptor modulators) for the treatment and prevention of benign hormone dependent gynecological disorders
ES2295050T3 (es) * 1999-08-31 2008-04-16 Bayer Schering Pharma Aktiengesellschaft Mesoprogestinas para el tratamiento y la prevencion de trastornos ginecologicos benignos dependientes de hormonas.
UA73119C2 (en) * 2000-04-19 2005-06-15 American Home Products Corpoir Derivatives of cyclic thiocarbamates, pharmaceutical composition including noted derivatives of cyclic thiocarbamates and active ingredients of medicines as modulators of progesterone receptors
AU2001295359A1 (en) * 2000-10-30 2002-05-15 University Of Zurich GnRH analogues for treatment of urinary incontinence
US6958142B2 (en) * 2002-08-02 2005-10-25 Balance Pharmaceuticals, Inc. Nasal spray formulation and method
US6960337B2 (en) * 2002-08-02 2005-11-01 Balance Pharmaceuticals, Inc. Methods and compositions for treating benign gynecological disorders
US7029657B2 (en) * 2002-08-02 2006-04-18 Balance Pharmaceuticals, Inc. Nasal spray steroid formulation and method
GB0302572D0 (en) 2003-02-05 2003-03-12 Astrazeneca Ab Method of treatment
EP1865935B1 (en) * 2005-02-17 2011-06-08 Hadasit Medical Research Services and Development Ltd. Bisphosphonates for treating endometriosis
US20060251581A1 (en) * 2005-05-09 2006-11-09 Mcintyre Jon T Method for treatment of uterine fibroid tumors
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
TWI455716B (zh) * 2006-10-24 2014-10-11 Repros Therapeutics Inc 選擇性黃體激素受體調節劑用於製造治療雌激素依賴性病症之藥物的用途
MY150763A (en) * 2006-10-24 2014-02-28 Repros Therapeutics Inc Compositions and methods for suppressing endometrial proliferation
WO2008144143A1 (en) * 2007-05-14 2008-11-27 Drugtech Corporation Endometriosis treatment
US20110208118A1 (en) * 2007-09-20 2011-08-25 Bio-Pro Medical Ltd. Compositions and means for treating uterine leiomyomata, leiomyoma, myoma, uterine fibroids, endometriosis, adenomyosis and related disorders by mifepristone
RU2359684C1 (ru) * 2008-01-23 2009-06-27 Закрытое акционерное общество "СКАЙ ЛТД" Способ лечения эндометриоза
US9993427B2 (en) 2013-03-14 2018-06-12 Biorest Ltd. Liposome formulation and manufacture
EP3560555A1 (en) 2018-04-26 2019-10-30 LifeArc A composition for treating one or more estrogen related diseases

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ZA8231B (en) 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
US4780461A (en) 1983-06-15 1988-10-25 Schering Aktiengesellschaft 13α-alkyl-gonanes, their production, and pharmaceutical preparations containing same
DE3347126A1 (de) 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
DE19975054I2 (de) 1987-08-08 2000-04-13 Akzo Nobel Nv Kontrazeptives Implantat
DE3744054A1 (de) 1987-12-21 1989-06-29 Schering Ag Verwendung von antigestagenen zur herstellung von arzneimitteln
DE3921059A1 (de) 1989-06-23 1991-01-10 Schering Ag 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel
EP0472725B1 (en) 1990-03-16 1997-05-21 Applied Research Systems Ars Holding N.V. Treatment of polycystic ovarian disease
US6827050B2 (en) 2001-12-21 2004-12-07 Caterpillar Inc Fluid control valve actuating system
US7283632B2 (en) 2003-09-09 2007-10-16 The Boeing Company Unauthorized access embedded software protection system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Ｊ．Ｓｔｅｒｏｉｄ Ｂｉｏｃｈｅｍ．Ｍｏｌｅｃ Ｂｉｏｌ．，Ｖｏｌ．３７，Ｎｏ．６（１９９０），ｐ．７８９−７９４

Also Published As

Publication number Publication date
BR9506606A (pt) 1997-09-09
CN1144486A (zh) 1997-03-05
LV11782A (lv) 1997-06-20
TJ242B (en) 1999-11-24
FI963036A0 (fi) 1996-08-01
FI963036A7 (fi) 1996-08-01
ES2132645T3 (es) 1999-08-16
SK96296A3 (en) 1997-07-09
OA10777A (en) 2002-12-23
MD1432C2 (ro) 2000-09-30
AU689229B2 (en) 1998-03-26
LT4182B (en) 1997-06-25
DE69509544D1 (de) 1999-06-10
DK0785792T3 (da) 1999-10-18
EP0785792B1 (en) 1999-05-06
DE69509544T2 (de) 1999-09-02
RO117420B1 (ro) 2002-03-29
BG62238B1 (bg) 1999-06-30
PL178273B1 (pl) 2000-03-31
BG100766A (bg) 1997-06-30
GR3030164T3 (en) 1999-08-31
MD1432B2 (en) 2000-03-31
CA2182183C (en) 2003-09-16
WO1995020972A1 (en) 1995-08-10
AP9600840A0 (en) 1996-07-31
EP0785792A4 (show.php) 1997-07-30
CA2182183A1 (en) 1995-08-10
US5681817A (en) 1997-10-28
CZ291709B6 (cs) 2003-05-14
EP0785792A1 (en) 1997-07-30
JPH09508418A (ja) 1997-08-26
FI963036L (fi) 1996-08-01
NZ281441A (en) 1999-09-29
RU2110274C1 (ru) 1998-05-10
ATE179610T1 (de) 1999-05-15
LT96133A (en) 1997-01-27
LV11782B (en) 1997-12-20
AU1838695A (en) 1995-08-21
CZ210396A3 (en) 1997-05-14
PL315792A1 (en) 1996-12-09
AP724A (en) 1999-01-18
KR970700507A (ko) 1997-02-12
HUT74622A (en) 1997-01-28
HU9601969D0 (en) 1996-09-30

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Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees