JP3097755B2 - 遷移金属の窒化物錯体の製造方法 - Google Patents

遷移金属の窒化物錯体の製造方法

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Publication number
JP3097755B2
JP3097755B2 JP03511871A JP51187191A JP3097755B2 JP 3097755 B2 JP3097755 B2 JP 3097755B2 JP 03511871 A JP03511871 A JP 03511871A JP 51187191 A JP51187191 A JP 51187191A JP 3097755 B2 JP3097755 B2 JP 3097755B2
Authority
JP
Japan
Prior art keywords
ligand
transition metal
group
tin
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP03511871A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05508842A (ja
Inventor
パスクワランイ，ロベルト
コマジ，ヴェロニク
ベランド，エマニュエル
Original Assignee
セ・イ・エス・ビオ・アンテルナショナル
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by セ・イ・エス・ビオ・アンテルナショナル filed Critical セ・イ・エス・ビオ・アンテルナショナル
Publication of JPH05508842A publication Critical patent/JPH05508842A/ja
Application granted granted Critical
Publication of JP3097755B2 publication Critical patent/JP3097755B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP03511871A 1990-07-04 1991-07-03 遷移金属の窒化物錯体の製造方法 Expired - Fee Related JP3097755B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9008473A FR2664166A1 (fr) 1990-07-04 1990-07-04 Procede de preparation de complexes nitruro de metaux de transition utilisables comme produits radiopharmaceutiques ou pour la synthese de nouveaux produits radiopharmaceutiques.
FR90/08473 1990-07-04
PCT/FR1991/000536 WO1992000982A1 (fr) 1990-07-04 1991-07-03 Procede de preparation de complexes nitruro de metaux de transition

Publications (2)

Publication Number Publication Date
JPH05508842A JPH05508842A (ja) 1993-12-09
JP3097755B2 true JP3097755B2 (ja) 2000-10-10

Family

ID=9398344

Family Applications (1)

Application Number Title Priority Date Filing Date
JP03511871A Expired - Fee Related JP3097755B2 (ja) 1990-07-04 1991-07-03 遷移金属の窒化物錯体の製造方法

Country Status (9)

Country Link
US (1) US5399339A (https=)
EP (1) EP0537242B1 (https=)
JP (1) JP3097755B2 (https=)
AU (1) AU8105491A (https=)
CA (1) CA2086426C (https=)
DE (1) DE69101708T2 (https=)
ES (1) ES2053330T3 (https=)
FR (1) FR2664166A1 (https=)
WO (1) WO1992000982A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2679452B1 (fr) * 1991-07-22 1993-11-12 Cis Bio International Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation.
US5750088A (en) * 1993-03-30 1998-05-12 The Dupont Merck Pharmaceutical Company Stable hydrazones linked to a peptide moiety as reagents for the preparation of radiopharmaceuticals
US5744120A (en) * 1993-03-30 1998-04-28 The Dupont Merick Pharmaceutical Company Ternary radiopharmaceutical complexes
CA2158249A1 (en) * 1993-03-31 1994-10-13 James W. Brodack Radiopharmaceutical formulations having non-stannous reductants
US5414620A (en) * 1993-08-09 1995-05-09 Honeywell Inc. Synthetic friction algorithm for a hand control element
US5751629A (en) 1995-04-25 1998-05-12 Irori Remotely programmable matrices with memories
US6416714B1 (en) 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
US5874214A (en) 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
US6017496A (en) 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
US6329139B1 (en) 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
US6331273B1 (en) 1995-04-25 2001-12-18 Discovery Partners International Remotely programmable matrices with memories
US6033645A (en) * 1996-06-19 2000-03-07 Unger; Evan C. Methods for diagnostic imaging by regulating the administration rate of a contrast agent
FR2736834B1 (fr) * 1995-07-17 1997-08-29 Cis Bio Int Produits radiopharmaceutiques a tropisme cardiaque comportant un complexe nitruro d'un metal de transition et ayant une clairance myocardique rapide
ATE239745T1 (de) 1996-12-18 2003-05-15 Nihon Mediphysics Co Ltd Nitrid-heterokomplexe von radioaktiven übergangsmetallen
KR100501534B1 (ko) * 1997-12-23 2005-10-26 정재민 방사성 동위원소 치료를 위한 방사성 레늄주석콜로이드 및 그 제법
DE60136073D1 (de) * 2000-07-28 2008-11-20 Nihon Mediphysics Co Ltd Technitium-99m nitrid hetero-komplex radiopharmazeutisches mittel zur bilderzeugung
EP1973923B1 (en) 2006-01-20 2011-08-17 Nihon Medi-Physics Co., Ltd. Intermediate compound of technetium nitride complex for radiodiagnostic imaging

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3484511D1 (de) * 1983-12-29 1991-05-29 Commw Of Australia Herstellung von mit 99m tc markierten radioarzneimitteln.
US5279811A (en) * 1987-02-18 1994-01-18 The Du Pont Merck Pharmaceutical Company Ester-substituted diaminedithiols and radiolabeled complexes thereof
CA1340899C (en) * 1988-03-09 2000-02-15 Andre Bardy Procede de preparation de complexes nitruro 99m tc, 186 re ou 188 re utilisables comme produits radiopharmaceutiques
JP3015970B2 (ja) * 1988-11-25 2000-03-06 セ・イ・エス・ビオ・アンテルナショナル・ソシエテ・アノニム 遷移金属の窒化物錯体を含んでいる、心臓への向性を特に有する放射性医薬製品およびその製造方法

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
"Ｊ．Ｒａｄｉｏａｎａｌ．Ｎｕｃｌ．Ｃｈｅｍ．，"（１９８６），Ｖｏｌ．１０５，Ｎｏ．５，ｐａｇｅｓ ２６７−２７６

Also Published As

Publication number Publication date
CA2086426A1 (fr) 1992-01-05
ES2053330T3 (es) 1994-07-16
DE69101708D1 (de) 1994-05-19
CA2086426C (fr) 2004-06-15
AU8105491A (en) 1992-02-04
US5399339A (en) 1995-03-21
DE69101708T2 (de) 1994-10-27
EP0537242A1 (fr) 1993-04-21
EP0537242B1 (fr) 1994-04-13
JPH05508842A (ja) 1993-12-09
WO1992000982A1 (fr) 1992-01-23
FR2664166A1 (fr) 1992-01-10
FR2664166B1 (https=) 1994-12-16

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