ATE239745T1 - Nitrid-heterokomplexe von radioaktiven übergangsmetallen - Google Patents
Nitrid-heterokomplexe von radioaktiven übergangsmetallenInfo
- Publication number
- ATE239745T1 ATE239745T1 AT97947953T AT97947953T ATE239745T1 AT E239745 T1 ATE239745 T1 AT E239745T1 AT 97947953 T AT97947953 T AT 97947953T AT 97947953 T AT97947953 T AT 97947953T AT E239745 T1 ATE239745 T1 AT E239745T1
- Authority
- AT
- Austria
- Prior art keywords
- radioactive
- radioactive transition
- transition metal
- transition metals
- present
- Prior art date
Links
- 230000002285 radioactive effect Effects 0.000 title abstract 6
- 229910052723 transition metal Inorganic materials 0.000 title abstract 4
- 150000003624 transition metals Chemical class 0.000 title abstract 2
- 150000004767 nitrides Chemical class 0.000 title 1
- -1 transition metal nitride Chemical class 0.000 abstract 4
- VURFVHCLMJOLKN-UHFFFAOYSA-N Diphosphine Natural products PP VURFVHCLMJOLKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 229910052702 rhenium Inorganic materials 0.000 abstract 1
- WUAPFZMCVAUBPE-UHFFFAOYSA-N rhenium atom Chemical compound [Re] WUAPFZMCVAUBPE-UHFFFAOYSA-N 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229910052713 technetium Inorganic materials 0.000 abstract 1
- GKLVYJBZJHMRIY-UHFFFAOYSA-N technetium atom Chemical compound [Tc] GKLVYJBZJHMRIY-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5004—Acyclic saturated phosphines
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Ceramic Products (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33855396 | 1996-12-18 | ||
| PCT/JP1997/004626 WO1998027100A1 (en) | 1996-12-18 | 1997-12-16 | Radioactive transition metal nitride hetero-complex |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE239745T1 true ATE239745T1 (de) | 2003-05-15 |
Family
ID=18319265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97947953T ATE239745T1 (de) | 1996-12-18 | 1997-12-16 | Nitrid-heterokomplexe von radioaktiven übergangsmetallen |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6270745B1 (de) |
| EP (1) | EP0949265B1 (de) |
| JP (1) | JP3935218B2 (de) |
| KR (1) | KR100554563B1 (de) |
| AT (1) | ATE239745T1 (de) |
| AU (1) | AU730120B2 (de) |
| CA (1) | CA2275451C (de) |
| DE (1) | DE69721820T2 (de) |
| DK (1) | DK0949265T3 (de) |
| ES (1) | ES2193407T3 (de) |
| NZ (1) | NZ335950A (de) |
| PT (1) | PT949265E (de) |
| WO (1) | WO1998027100A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5855867A (en) * | 1995-03-29 | 1999-01-05 | The Curators Of The University Of Missouri | Hydroxymethyl phosphine compounds for use as diagnostic and therapeutic pharmaceuticals and method of making same |
| AU3922601A (en) * | 2000-01-28 | 2001-08-07 | Molypharma, S.A. | A radiopharmaceutical for radionuclide tumor therapy |
| DE60136073D1 (de) * | 2000-07-28 | 2008-11-20 | Nihon Mediphysics Co Ltd | Technitium-99m nitrid hetero-komplex radiopharmazeutisches mittel zur bilderzeugung |
| JP4266827B2 (ja) | 2001-12-20 | 2009-05-20 | サソル テクノロジー （ピーティーワイ）リミテッド | クロムを主成分とした触媒を使用したオレフィン類の三量化およびオリゴマー化 |
| US8980870B2 (en) * | 2002-09-24 | 2015-03-17 | Boehringer Ingelheim International Gmbh | Solid telmisartan pharmaceutical formulations |
| EP1417977A1 (de) * | 2002-11-07 | 2004-05-12 | BRACCO IMAGING S.p.A. | Radioaktive Übergangsmetall-Imido-Heterodiphosphinkomplexe; deren Herstellung und radiopharmazeutische Zusammensetzungen |
| WO2004096735A2 (en) * | 2003-05-02 | 2004-11-11 | Kamaluddin Abdur-Rashid | Transfer hydrogenation processes and catalysts |
| JP2008037752A (ja) * | 2004-11-19 | 2008-02-21 | Nihon Medi Physics Co Ltd | 新規放射性テクネチウム−ビスホスフィノアミン錯体および該錯体を含む放射性画像診断剤 |
| WO2006080993A1 (en) * | 2004-12-08 | 2006-08-03 | Purdue Research Foundation | Novel cationic metal complex radiopharmaceuticals |
| WO2007083395A1 (en) | 2006-01-20 | 2007-07-26 | Nihon Medi-Physics Co., Ltd. | Intermediate compound of technetium nitride complex for radiodiagnostic imaging |
| US20130195756A1 (en) | 2012-01-31 | 2013-08-01 | General Electric Company | 99mTc IMAGING AGENTS AND METHODS OF USE |
| WO2018109164A1 (en) | 2016-12-15 | 2018-06-21 | Bracco Imaging Spa | Method for labeling of sensitive and thermosensitive targeting biomolecules with technetium based compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8723438D0 (en) * | 1987-10-06 | 1987-11-11 | Amersham Int Plc | Cationic complexes of technetium-99m |
| WO1989008657A2 (fr) * | 1988-03-09 | 1989-09-21 | Cis Bio Internatonal | Preparation de complexes nitruro utilisables comme produits radiopharmaceutiques |
| FR2664166A1 (fr) | 1990-07-04 | 1992-01-10 | Cis Bio Int | Procede de preparation de complexes nitruro de metaux de transition utilisables comme produits radiopharmaceutiques ou pour la synthese de nouveaux produits radiopharmaceutiques. |
| FR2679452B1 (fr) | 1991-07-22 | 1993-11-12 | Cis Bio International | Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation. |
| JPH07110869A (ja) | 1993-10-12 | 1995-04-25 | Fuji Xerox Co Ltd | 図形編集装置 |
-
1997
- 1997-12-16 CA CA002275451A patent/CA2275451C/en not_active Expired - Fee Related
- 1997-12-16 JP JP52753998A patent/JP3935218B2/ja not_active Expired - Fee Related
- 1997-12-16 KR KR1019997005482A patent/KR100554563B1/ko not_active Expired - Fee Related
- 1997-12-16 WO PCT/JP1997/004626 patent/WO1998027100A1/ja not_active Ceased
- 1997-12-16 PT PT97947953T patent/PT949265E/pt unknown
- 1997-12-16 US US09/331,237 patent/US6270745B1/en not_active Expired - Lifetime
- 1997-12-16 DE DE69721820T patent/DE69721820T2/de not_active Expired - Lifetime
- 1997-12-16 AT AT97947953T patent/ATE239745T1/de not_active IP Right Cessation
- 1997-12-16 DK DK97947953T patent/DK0949265T3/da active
- 1997-12-16 AU AU54128/98A patent/AU730120B2/en not_active Ceased
- 1997-12-16 ES ES97947953T patent/ES2193407T3/es not_active Expired - Lifetime
- 1997-12-16 EP EP97947953A patent/EP0949265B1/de not_active Expired - Lifetime
- 1997-12-16 NZ NZ335950A patent/NZ335950A/en not_active IP Right Cessation
-
2001
- 2001-07-16 US US09/838,254 patent/US20020048549A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP3935218B2 (ja) | 2007-06-20 |
| PT949265E (pt) | 2003-08-29 |
| EP0949265B1 (de) | 2003-05-07 |
| KR20000057661A (ko) | 2000-09-25 |
| US6270745B1 (en) | 2001-08-07 |
| DK0949265T3 (da) | 2003-08-11 |
| NZ335950A (en) | 2000-06-23 |
| AU5412898A (en) | 1998-07-15 |
| EP0949265A1 (de) | 1999-10-13 |
| CA2275451C (en) | 2007-01-02 |
| AU730120B2 (en) | 2001-02-22 |
| WO1998027100A1 (en) | 1998-06-25 |
| US20020048549A1 (en) | 2002-04-25 |
| DE69721820T2 (de) | 2004-02-26 |
| CA2275451A1 (en) | 1998-06-25 |
| ES2193407T3 (es) | 2003-11-01 |
| KR100554563B1 (ko) | 2006-03-03 |
| DE69721820D1 (de) | 2003-06-12 |
| EP0949265A4 (de) | 2001-03-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0949265 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |