DK0949265T3 - Nitrid-heterokomplekser af radioaktive overgangsmetaller - Google Patents

Nitrid-heterokomplekser af radioaktive overgangsmetaller

Info

Publication number
DK0949265T3
DK0949265T3 DK97947953T DK97947953T DK0949265T3 DK 0949265 T3 DK0949265 T3 DK 0949265T3 DK 97947953 T DK97947953 T DK 97947953T DK 97947953 T DK97947953 T DK 97947953T DK 0949265 T3 DK0949265 T3 DK 0949265T3
Authority
DK
Denmark
Prior art keywords
radioactive
radioactive transition
transition metal
transition metals
present
Prior art date
Application number
DK97947953T
Other languages
English (en)
Inventor
Adriano Duatti
Cristina Bolzati
Licia Uccelli
Fiorenzo Refosco
Francesco Tisato
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Application granted granted Critical
Publication of DK0949265T3 publication Critical patent/DK0949265T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/50Organo-phosphines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005Compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0474Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/50Organo-phosphines
    • C07F9/5004Acyclic saturated phosphines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ceramic Products (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK97947953T 1996-12-18 1997-12-16 Nitrid-heterokomplekser af radioaktive overgangsmetaller DK0949265T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP33855396 1996-12-18
PCT/JP1997/004626 WO1998027100A1 (fr) 1996-12-18 1997-12-16 Heterocomplexe a nitrure de metal de transition radioactif

Publications (1)

Publication Number Publication Date
DK0949265T3 true DK0949265T3 (da) 2003-08-11

Family

ID=18319265

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97947953T DK0949265T3 (da) 1996-12-18 1997-12-16 Nitrid-heterokomplekser af radioaktive overgangsmetaller

Country Status (13)

Country Link
US (2) US6270745B1 (da)
EP (1) EP0949265B1 (da)
JP (1) JP3935218B2 (da)
KR (1) KR100554563B1 (da)
AT (1) ATE239745T1 (da)
AU (1) AU730120B2 (da)
CA (1) CA2275451C (da)
DE (1) DE69721820T2 (da)
DK (1) DK0949265T3 (da)
ES (1) ES2193407T3 (da)
NZ (1) NZ335950A (da)
PT (1) PT949265E (da)
WO (1) WO1998027100A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5855867A (en) * 1995-03-29 1999-01-05 The Curators Of The University Of Missouri Hydroxymethyl phosphine compounds for use as diagnostic and therapeutic pharmaceuticals and method of making same
AU3922601A (en) * 2000-01-28 2001-08-07 Molypharma, S.A. A radiopharmaceutical for radionuclide tumor therapy
US7445765B2 (en) * 2000-07-28 2008-11-04 Nihon Medi-Physics Co., Ltd. Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex
CN1606539A (zh) * 2001-12-20 2005-04-13 Sasol技术股份有限公司 使用铬基催化剂的烯烃寡聚和三聚
US8980870B2 (en) * 2002-09-24 2015-03-17 Boehringer Ingelheim International Gmbh Solid telmisartan pharmaceutical formulations
EP1417977A1 (en) * 2002-11-07 2004-05-12 BRACCO IMAGING S.p.A. Radioactive transition metal-imido hetero-diphosphine complexes, their preparation and radiopharmaceutical compositions thereof
CA2565130C (en) * 2003-05-02 2011-03-15 Kamaluddin Abdur-Rashid Transfer hydrogenation processes and catalysts
JP2008037752A (ja) * 2004-11-19 2008-02-21 Nihon Medi Physics Co Ltd 新規放射性テクネチウム−ビスホスフィノアミン錯体および該錯体を含む放射性画像診断剤
WO2006080993A1 (en) * 2004-12-08 2006-08-03 Purdue Research Foundation Novel cationic metal complex radiopharmaceuticals
ES2369027T3 (es) * 2006-01-20 2011-11-24 Nihon Medi-Physics Co., Ltd. Compuesto intermedio de un complejo de nitruro de tecnecio para la formación de imágenes radiodiagnósticas.
US20130195756A1 (en) 2012-01-31 2013-08-01 General Electric Company 99mTc IMAGING AGENTS AND METHODS OF USE
US11160886B2 (en) 2016-12-15 2021-11-02 Bracco Imaging Spa Method for labeling of sensitive and thermosensitive targeting biomolecules with technetium based compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8723438D0 (en) * 1987-10-06 1987-11-11 Amersham Int Plc Cationic complexes of technetium-99m
EP0403524B1 (fr) * 1988-03-09 1993-02-10 Cis Bio International Preparation de complexes nitruro utilisables comme produits radiopharmaceutiques
FR2664166A1 (fr) 1990-07-04 1992-01-10 Cis Bio Int Procede de preparation de complexes nitruro de metaux de transition utilisables comme produits radiopharmaceutiques ou pour la synthese de nouveaux produits radiopharmaceutiques.
FR2679452B1 (fr) * 1991-07-22 1993-11-12 Cis Bio International Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation.
JPH07110869A (ja) 1993-10-12 1995-04-25 Fuji Xerox Co Ltd 図形編集装置

Also Published As

Publication number Publication date
DE69721820D1 (de) 2003-06-12
CA2275451A1 (en) 1998-06-25
EP0949265A4 (en) 2001-03-07
ATE239745T1 (de) 2003-05-15
PT949265E (pt) 2003-08-29
AU730120B2 (en) 2001-02-22
JP3935218B2 (ja) 2007-06-20
US20020048549A1 (en) 2002-04-25
ES2193407T3 (es) 2003-11-01
AU5412898A (en) 1998-07-15
KR20000057661A (ko) 2000-09-25
EP0949265A1 (en) 1999-10-13
EP0949265B1 (en) 2003-05-07
NZ335950A (en) 2000-06-23
CA2275451C (en) 2007-01-02
US6270745B1 (en) 2001-08-07
DE69721820T2 (de) 2004-02-26
WO1998027100A1 (fr) 1998-06-25
KR100554563B1 (ko) 2006-03-03

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