DE69721820D1 - Nitrid-heterokomplexe von radioaktiven übergangsmetallen - Google Patents
Nitrid-heterokomplexe von radioaktiven übergangsmetallenInfo
- Publication number
- DE69721820D1 DE69721820D1 DE69721820T DE69721820T DE69721820D1 DE 69721820 D1 DE69721820 D1 DE 69721820D1 DE 69721820 T DE69721820 T DE 69721820T DE 69721820 T DE69721820 T DE 69721820T DE 69721820 D1 DE69721820 D1 DE 69721820D1
- Authority
- DE
- Germany
- Prior art keywords
- radioactive
- radioactive transition
- transition metal
- transition metals
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000002285 radioactive effect Effects 0.000 title abstract 6
- 229910052723 transition metal Inorganic materials 0.000 title abstract 4
- 150000003624 transition metals Chemical class 0.000 title abstract 2
- 150000004767 nitrides Chemical class 0.000 title 1
- -1 transition metal nitride Chemical class 0.000 abstract 4
- VURFVHCLMJOLKN-UHFFFAOYSA-N Diphosphine Natural products PP VURFVHCLMJOLKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 229910052702 rhenium Inorganic materials 0.000 abstract 1
- WUAPFZMCVAUBPE-UHFFFAOYSA-N rhenium atom Chemical compound [Re] WUAPFZMCVAUBPE-UHFFFAOYSA-N 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229910052713 technetium Inorganic materials 0.000 abstract 1
- GKLVYJBZJHMRIY-UHFFFAOYSA-N technetium atom Chemical compound [Tc] GKLVYJBZJHMRIY-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
- C07F13/005—Compounds without a metal-carbon linkage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/50—Organo-phosphines
- C07F9/5004—Acyclic saturated phosphines
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Ceramic Products (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP33855396 | 1996-12-18 | ||
| JP33855396 | 1996-12-18 | ||
| PCT/JP1997/004626 WO1998027100A1 (fr) | 1996-12-18 | 1997-12-16 | Heterocomplexe a nitrure de metal de transition radioactif |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69721820D1 true DE69721820D1 (de) | 2003-06-12 |
| DE69721820T2 DE69721820T2 (de) | 2004-02-26 |
Family
ID=18319265
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69721820T Expired - Lifetime DE69721820T2 (de) | 1996-12-18 | 1997-12-16 | Nitrid-heterokomplexe von radioaktiven übergangsmetallen |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US6270745B1 (de) |
| EP (1) | EP0949265B1 (de) |
| JP (1) | JP3935218B2 (de) |
| KR (1) | KR100554563B1 (de) |
| AT (1) | ATE239745T1 (de) |
| AU (1) | AU730120B2 (de) |
| CA (1) | CA2275451C (de) |
| DE (1) | DE69721820T2 (de) |
| DK (1) | DK0949265T3 (de) |
| ES (1) | ES2193407T3 (de) |
| NZ (1) | NZ335950A (de) |
| PT (1) | PT949265E (de) |
| WO (1) | WO1998027100A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5855867A (en) * | 1995-03-29 | 1999-01-05 | The Curators Of The University Of Missouri | Hydroxymethyl phosphine compounds for use as diagnostic and therapeutic pharmaceuticals and method of making same |
| AU3922601A (en) * | 2000-01-28 | 2001-08-07 | Molypharma, S.A. | A radiopharmaceutical for radionuclide tumor therapy |
| CA2417392C (en) * | 2000-07-28 | 2007-09-11 | Nihon Medi-Physics Co., Ltd. | Radiopharmaceutical for diagnostic imaging containing a technetium-99m nitride heterocomplex |
| JP4266827B2 (ja) * | 2001-12-20 | 2009-05-20 | サソル テクノロジー （ピーティーワイ）リミテッド | クロムを主成分とした触媒を使用したオレフィン類の三量化およびオリゴマー化 |
| US8980870B2 (en) * | 2002-09-24 | 2015-03-17 | Boehringer Ingelheim International Gmbh | Solid telmisartan pharmaceutical formulations |
| EP1417977A1 (de) * | 2002-11-07 | 2004-05-12 | BRACCO IMAGING S.p.A. | Radioaktive Übergangsmetall-Imido-Heterodiphosphinkomplexe; deren Herstellung und radiopharmazeutische Zusammensetzungen |
| WO2004096735A2 (en) * | 2003-05-02 | 2004-11-11 | Kamaluddin Abdur-Rashid | Transfer hydrogenation processes and catalysts |
| JP2008037752A (ja) * | 2004-11-19 | 2008-02-21 | Nihon Medi Physics Co Ltd | 新規放射性テクネチウム−ビスホスフィノアミン錯体および該錯体を含む放射性画像診断剤 |
| WO2006080993A1 (en) * | 2004-12-08 | 2006-08-03 | Purdue Research Foundation | Novel cationic metal complex radiopharmaceuticals |
| JP5027144B2 (ja) * | 2006-01-20 | 2012-09-19 | 日本メジフィジックス株式会社 | 放射性画像診断のための窒化テクネチウム錯体の中間体化合物 |
| US20130195756A1 (en) | 2012-01-31 | 2013-08-01 | General Electric Company | 99mTc IMAGING AGENTS AND METHODS OF USE |
| CN110072560A (zh) * | 2016-12-15 | 2019-07-30 | 伯拉考成像股份公司 | 用于利用基于锝的化合物标记敏感和热敏性靶向生物分子的方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8723438D0 (en) * | 1987-10-06 | 1987-11-11 | Amersham Int Plc | Cationic complexes of technetium-99m |
| AU619538B2 (en) * | 1988-03-09 | 1992-01-30 | Cis Bio International | Preparation of nitruro compounds usable as radio-pharmaceutical products |
| FR2664166A1 (fr) * | 1990-07-04 | 1992-01-10 | Cis Bio Int | Procede de preparation de complexes nitruro de metaux de transition utilisables comme produits radiopharmaceutiques ou pour la synthese de nouveaux produits radiopharmaceutiques. |
| FR2679452B1 (fr) | 1991-07-22 | 1993-11-12 | Cis Bio International | Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation. |
| JPH07110869A (ja) | 1993-10-12 | 1995-04-25 | Fuji Xerox Co Ltd | 図形編集装置 |
-
1997
- 1997-12-16 JP JP52753998A patent/JP3935218B2/ja not_active Expired - Fee Related
- 1997-12-16 DE DE69721820T patent/DE69721820T2/de not_active Expired - Lifetime
- 1997-12-16 ES ES97947953T patent/ES2193407T3/es not_active Expired - Lifetime
- 1997-12-16 KR KR1019997005482A patent/KR100554563B1/ko not_active IP Right Cessation
- 1997-12-16 EP EP97947953A patent/EP0949265B1/de not_active Expired - Lifetime
- 1997-12-16 WO PCT/JP1997/004626 patent/WO1998027100A1/ja not_active Application Discontinuation
- 1997-12-16 PT PT97947953T patent/PT949265E/pt unknown
- 1997-12-16 NZ NZ335950A patent/NZ335950A/en not_active IP Right Cessation
- 1997-12-16 DK DK97947953T patent/DK0949265T3/da active
- 1997-12-16 US US09/331,237 patent/US6270745B1/en not_active Expired - Lifetime
- 1997-12-16 CA CA002275451A patent/CA2275451C/en not_active Expired - Fee Related
- 1997-12-16 AU AU54128/98A patent/AU730120B2/en not_active Ceased
- 1997-12-16 AT AT97947953T patent/ATE239745T1/de not_active IP Right Cessation
-
2001
- 2001-07-16 US US09/838,254 patent/US20020048549A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NZ335950A (en) | 2000-06-23 |
| EP0949265A1 (de) | 1999-10-13 |
| DE69721820T2 (de) | 2004-02-26 |
| AU5412898A (en) | 1998-07-15 |
| PT949265E (pt) | 2003-08-29 |
| US20020048549A1 (en) | 2002-04-25 |
| ATE239745T1 (de) | 2003-05-15 |
| ES2193407T3 (es) | 2003-11-01 |
| KR20000057661A (ko) | 2000-09-25 |
| CA2275451A1 (en) | 1998-06-25 |
| WO1998027100A1 (fr) | 1998-06-25 |
| KR100554563B1 (ko) | 2006-03-03 |
| AU730120B2 (en) | 2001-02-22 |
| DK0949265T3 (da) | 2003-08-11 |
| EP0949265A4 (de) | 2001-03-07 |
| US6270745B1 (en) | 2001-08-07 |
| JP3935218B2 (ja) | 2007-06-20 |
| CA2275451C (en) | 2007-01-02 |
| EP0949265B1 (de) | 2003-05-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: NIHON MEDI-PHYSICS CO., LTD., TOKYO, JP |