JP3026602B2 - 植物油ベースの皮膚透過促進剤組成物,およびそれに関連する方法ならびにシステム - Google Patents

植物油ベースの皮膚透過促進剤組成物,およびそれに関連する方法ならびにシステム

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Publication number
JP3026602B2
JP3026602B2 JP5511695A JP51169592A JP3026602B2 JP 3026602 B2 JP3026602 B2 JP 3026602B2 JP 5511695 A JP5511695 A JP 5511695A JP 51169592 A JP51169592 A JP 51169592A JP 3026602 B2 JP3026602 B2 JP 3026602B2
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Japan
Prior art keywords
oil
drug
weight
composition
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP5511695A
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English (en)
Japanese (ja)
Other versions
JPH07506562A (ja
Inventor
シャーマ,クルディーパック
ジェイ. ルーズ,エリック
エム. ダンバー,ダース
Original Assignee
シグナス,インコーポレイテッド
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Application filed by シグナス,インコーポレイテッド filed Critical シグナス,インコーポレイテッド
Publication of JPH07506562A publication Critical patent/JPH07506562A/ja
Application granted granted Critical
Publication of JP3026602B2 publication Critical patent/JP3026602B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
JP5511695A 1991-12-20 1992-12-10 植物油ベースの皮膚透過促進剤組成物,およびそれに関連する方法ならびにシステム Expired - Lifetime JP3026602B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US810963 1991-12-20
US07/810,963 US5229130A (en) 1991-12-20 1991-12-20 Vegetable oil-based skin permeation enhancer compositions, and associated methods and systems
PCT/US1992/010673 WO1993012744A1 (en) 1991-12-20 1992-12-10 Vegetable oil-based skin permeation enhancer compositions, and associated methods and systems

Publications (2)

Publication Number Publication Date
JPH07506562A JPH07506562A (ja) 1995-07-20
JP3026602B2 true JP3026602B2 (ja) 2000-03-27

Family

ID=25205155

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5511695A Expired - Lifetime JP3026602B2 (ja) 1991-12-20 1992-12-10 植物油ベースの皮膚透過促進剤組成物,およびそれに関連する方法ならびにシステム

Country Status (7)

Country Link
US (1) US5229130A (enrdf_load_stackoverflow)
EP (1) EP0617600A4 (enrdf_load_stackoverflow)
JP (1) JP3026602B2 (enrdf_load_stackoverflow)
AU (1) AU3247293A (enrdf_load_stackoverflow)
CA (1) CA2126214A1 (enrdf_load_stackoverflow)
TW (1) TW262385B (enrdf_load_stackoverflow)
WO (1) WO1993012744A1 (enrdf_load_stackoverflow)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09501414A (ja) * 1993-06-23 1997-02-10 ジョン ジェイ. マシズ 分子経皮搬送方式
US5645854A (en) * 1993-06-23 1997-07-08 Masiz; John J. Molecular transdermal transport system
US5460821A (en) * 1993-06-23 1995-10-24 Masiz; John J. Molecular transdermal transport system
US5853751A (en) * 1993-06-23 1998-12-29 Masiz; John J. Molecular transdermal transport system
US5627216A (en) * 1994-02-07 1997-05-06 Papadopoulos; George D. Medicinal ointment for hemorrhoid and skin care
DE4407742C1 (de) * 1994-03-08 1995-06-22 Hexal Pharma Gmbh Transdermales System in Form eines Pflasters mit einem Tamoxifen-Derivat
US5516517A (en) 1994-05-02 1996-05-14 Exfoliation Cleansing Hydration Oxygenation Corporation Method for nutritional oxygenation of the skin
US5849729A (en) * 1995-12-26 1998-12-15 Hershey Foods Corporation Use of hydrolyzed cocoa butter for percutaneous absorption
US5837227A (en) * 1995-12-26 1998-11-17 Hershey Foods Corporation Use of cocoa butter or partially hydrolyzed cocoa butter for the treatment of burns and wounds
US5968547A (en) 1997-02-24 1999-10-19 Euro-Celtique, S.A. Method of providing sustained analgesia with buprenorphine
IT1294748B1 (it) * 1997-09-17 1999-04-12 Permatec Tech Ag Formulazione per un dispositivo transdermico
US6423334B1 (en) * 1997-10-01 2002-07-23 Elan Corporation, Plc Composition and method for enhancing transport across gastrointestinal tract cell layers
CA2225352C (en) * 1998-01-30 2003-10-21 Nam Fong Han Vegetable derived petroleum jelly replacement
GB2344520A (en) * 1998-12-08 2000-06-14 Phares Pharm Res Nv Pharmaceutical carriers comprising lipids and polymers
US6093417A (en) * 1999-01-11 2000-07-25 Advanced Medical Instruments Composition to treat ear disorders
US6552024B1 (en) 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
US20070148228A1 (en) * 1999-02-22 2007-06-28 Merrion Research I Limited Solid oral dosage form containing an enhancer
US8119159B2 (en) * 1999-02-22 2012-02-21 Merrion Research Iii Limited Solid oral dosage form containing an enhancer
US7658938B2 (en) 1999-02-22 2010-02-09 Merrion Reasearch III Limited Solid oral dosage form containing an enhancer
US6399093B1 (en) 1999-05-19 2002-06-04 Advanced Medical Instruments Method and composition to treat musculoskeletal disorders
DE19927229B4 (de) * 1999-06-10 2004-09-09 Coty B.V. Enzymhaltiges Kosmetikum und dessen Verwendung
US6573299B1 (en) 1999-09-20 2003-06-03 Advanced Medical Instruments Method and compositions for treatment of the aging eye
US6455066B1 (en) 2000-03-10 2002-09-24 Epicept Corporation Intradermal-penetration agents for topical local anesthetic administration
US6635274B1 (en) * 2000-10-27 2003-10-21 Biochemics, Inc. Solution-based transdermal drug delivery system
WO2002092069A1 (en) * 2001-05-11 2002-11-21 Elan Corporation, Plc Permeation enhancers
CA2446622C (en) * 2001-05-11 2012-08-14 Elan Corporation, Plc Isostearic acid salts as permeation enhancers
US6559182B1 (en) * 2001-11-07 2003-05-06 Purcell Jojoba International, Llc Method for treatment of enveloped viruses using jojoba oil esters
US20040033253A1 (en) * 2002-02-19 2004-02-19 Ihor Shevchuk Acyl opioid antagonists
DE50310279D1 (de) * 2002-03-06 2008-09-18 Hexal Ag Transdermalsystem mit fentanyl
US7572469B2 (en) * 2002-04-15 2009-08-11 Tetsuo Santo Therapeutic lotion for dermatitis
JP4515098B2 (ja) * 2002-04-15 2010-07-28 哲夫 山東 皮膚炎治療用クリーム
CN100525767C (zh) 2002-06-10 2009-08-12 欧洲凯尔特公司 防止所含活性剂被误用的经皮给药器的处置系统
PT1530469E (pt) * 2002-08-20 2009-05-19 Euro Celtique Sa Forma de dosagem transdérmica que compreende um agente activo, um sal e uma forma de base livre de um antagonista
US20040258740A1 (en) * 2003-04-10 2004-12-23 Nene Labs Transdermal delivery composition
US20080020028A1 (en) * 2003-08-20 2008-01-24 Euro-Celtique S.A. Transdermal dosage form comprising an active agent and a salt and a free-base form of an adverse agent
US20060233739A1 (en) * 2003-11-24 2006-10-19 Thornfeldt Carl R Treatment of mucocutaneous disorders through reversing chronic imflammation and barrier disruption
US8252319B2 (en) 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
NZ582975A (en) 2004-10-21 2011-07-29 Durect Corp Transdermal delivery systems delivering sufentanil
WO2006091697A1 (en) 2005-02-23 2006-08-31 Psychenomics, Inc. Dopamine transporter inhibitors for use in treatment of movement disorders and other cns indications
US20070087055A1 (en) * 2005-10-14 2007-04-19 David Jan Directly compressible extended release alprazolam formulation
EP2526950A1 (en) * 2006-04-07 2012-11-28 Merrion Research III Limited Solid oral dosage form containing an enhancer
US20070292512A1 (en) * 2006-06-09 2007-12-20 Merrion Research Ii Limited Solid Oral Dosage Form Containing an Enhancer
US7282225B1 (en) 2006-09-27 2007-10-16 Occular Technologies, Inc. Composition and methods for improving retinal health
DE102006048130A1 (de) * 2006-10-06 2008-04-10 Axxonis Pharma Ag Transdermales therapeutisches System mit zweiphasigem Freisetzungsprofil
US20080152592A1 (en) * 2006-12-21 2008-06-26 Bayer Healthcare Llc Method of therapeutic drug monitoring
WO2008106571A2 (en) 2007-02-28 2008-09-04 Abbott Laboratories Sustained release parenteral formulations of buprenorphine
US20080226698A1 (en) * 2007-03-16 2008-09-18 Mylan Technologies, Inc. Amorphous drug transdermal systems, manufacturing methods, and stabilization
WO2008115224A2 (en) * 2007-03-20 2008-09-25 Bayer Healthcare Llc Method of analyzing an analyte
US20090142528A1 (en) 2007-08-18 2009-06-04 Earth First Industries Incorporated Composites for packaging articles and method of making same
US20090111780A1 (en) * 2007-10-31 2009-04-30 Everett Laboratories, Inc. Compositions and methods for treatment of ear canal infection and inflammation
US20090123504A1 (en) * 2007-11-12 2009-05-14 Kimberly-Clark Worldwide, Inc. Olive oil formulation for pain relief
US20090130048A1 (en) * 2007-11-19 2009-05-21 Oronsky Bryan Todd Topical Composition for Treating Pain
US20090227461A1 (en) * 2008-03-06 2009-09-10 Roberto Carpentier Preventing and/or Reducing "Lenticel Breakdown" Physiological Disorder in Apples by Applying Pre-Harvest Coatings
EP2271301A4 (en) 2008-03-27 2014-07-02 Agigma Inc METHOD AND COMPOSITIONS FOR THE DELIVERY OF FUNDS
TW200950801A (en) 2008-05-07 2009-12-16 Merrion Res Iii Ltd Compositions of peptides and processes of preparation thereof
CA2727710C (en) * 2008-06-11 2016-11-01 Biochemics, Inc. Control of blood vessel physiology to treat skin disorders
WO2010005507A1 (en) 2008-06-30 2010-01-14 Afgin Pharma, Llc Topical regional neuro-affective therapy
EP2373346B1 (en) 2008-09-10 2019-06-12 BioChemics, Inc. Ibuprofen for topical administration
US9566256B2 (en) * 2008-09-22 2017-02-14 Biochemics, Inc. Transdermal drug delivery using an osmolyte and vasoactive agent
EP2349230A2 (en) 2008-10-06 2011-08-03 Mylan Technologies, Inc. Amorphous rotigotine transdermal system
US9278233B2 (en) * 2008-12-04 2016-03-08 Biochemics, Inc. Methods and compositions for tattoo removal
CA2748788C (en) 2009-01-05 2021-02-09 Epitogenesis Inc. The use of a composition comprising mustard oil, catechin, and vitamin a for modulating an immune response
TWI480286B (zh) * 2009-02-25 2015-04-11 Merrion Res Iii Ltd 雙膦酸鹽類組合物及藥物遞送
DE102009013469B4 (de) 2009-03-19 2014-04-17 Bubbles And Beyond Gmbh Zubereitung zur äußerlichen Anwendung
US20110182985A1 (en) * 2010-01-28 2011-07-28 Coughlan David C Solid Pharmaceutical Composition with Enhancers and Methods of Preparing thereof
US8685472B2 (en) 2010-03-01 2014-04-01 Access Business Group International Llc Skin whitening composition containing chia seed extract
US9089484B2 (en) * 2010-03-26 2015-07-28 Merrion Research Iii Limited Pharmaceutical compositions of selective factor Xa inhibitors for oral administration
US8409636B2 (en) 2010-09-29 2013-04-02 Access Business Group International Llc Chia seed extract and related method of manufacture
JP2014501784A (ja) 2011-01-07 2014-01-23 メリオン・リサーチ・Iii・リミテッド 経口投与用の鉄の医薬組成物
ES2642274T3 (es) * 2011-02-02 2017-11-16 Nitto Denko Corporation Preparación de parche
WO2012105624A1 (ja) * 2011-02-02 2012-08-09 大日本住友製薬株式会社 経皮吸収用貼付製剤
EP2723378A4 (en) 2011-06-24 2015-01-28 Epitogenesis Inc PHARMACEUTICAL COMPOSITIONS COMPRISING A COMBINATION OF VECTORS, VITAMINS, TANNINS AND FLAVONOIDS SELECTED AS ANTIGEN-SPECIFIC IMMUNOMODULATORS
DE102012000369A1 (de) * 2012-01-11 2013-07-11 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Transdermales therapeutisches System mit Cholinesterase-Hemmer
EP2804606B1 (en) 2012-01-19 2017-06-28 Hybrid Medical, LLC Topical therapeutic formulations
US10471131B2 (en) 2012-01-19 2019-11-12 Hybrid Medical, Llc Topical therapeutic formulations
EP2978412A2 (en) * 2013-03-25 2016-02-03 Sloan Kettering Institute For Cancer Research Articles and methods for preventing and treating dermatologic adverse events
WO2015088990A1 (en) 2013-12-09 2015-06-18 Durect Corporation Pharmaceutically active agent complexes, polymer complexes, and compositions and methods involving the same
WO2016027216A2 (en) * 2014-08-22 2016-02-25 Venna Gopal A synergistic edible oil composition
CN107205948B (zh) 2015-01-29 2021-12-14 诺和诺德股份有限公司 包含glp-1激动剂和肠溶衣的片剂
GB2537647A (en) * 2015-04-22 2016-10-26 Cosmetic Warriors Ltd Composition
JP7325792B2 (ja) * 2017-06-30 2023-08-15 三省製薬株式会社 皮膚透過性促進剤および皮膚外用剤
RU2697411C2 (ru) * 2017-10-11 2019-08-14 федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) Композиция для лечения болезни Паркинсона
CA3094710A1 (en) * 2018-03-29 2019-10-03 Lumosa Therapeutics Co., Ltd. Compositions and methods for treating pruritus
AU2019285719B2 (en) 2018-06-11 2021-03-25 The Regents Of The University Of California Demethylation to treat eye disease
WO2020237244A1 (en) * 2019-05-23 2020-11-26 Professional Compounding Centers Of America, Inc. Skin permeation enhancing composition

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3551554A (en) * 1968-08-16 1970-12-29 Crown Zellerbach Corp Enhancing tissue penetration of physiologically active agents with dmso
US3472931A (en) * 1969-01-17 1969-10-14 Foster Milburn Co Percutaneous absorption with lower alkyl amides
DE2446162A1 (de) * 1974-09-27 1976-04-15 Schlafhorst & Co W Verfahren und vorrichtung zum zufuehren leerer konischer spulenhuelsen zu den einzelnen spulstellen einer textilmaschine
US3989816A (en) * 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
US4405616A (en) * 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US4316893A (en) * 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
CA1165240A (en) * 1980-07-09 1984-04-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions
US4379454A (en) * 1981-02-17 1983-04-12 Alza Corporation Dosage for coadministering drug and percutaneous absorption enhancer
US4440777A (en) * 1981-07-07 1984-04-03 Merck & Co., Inc. Use of eucalyptol for enhancing skin permeation of bio-affecting agents
US4552872A (en) * 1983-06-21 1985-11-12 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing corticosteroids
US4557934A (en) * 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
US4537776A (en) * 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
JPS60174716A (ja) * 1984-02-21 1985-09-09 Yamanouchi Pharmaceut Co Ltd パツチ剤
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
US4568343A (en) * 1984-10-09 1986-02-04 Alza Corporation Skin permeation enhancer compositions
US4908389A (en) * 1986-08-27 1990-03-13 Warner-Lambert Company Penetration enhancement system
ATE68704T1 (de) * 1986-12-18 1991-11-15 Bauer Kurt Heinz Gegenueber lichteinfluss stabilisiertes nifedipin- konzentrat und verfahren zu seiner herstellung.
AU601528B2 (en) * 1986-12-22 1990-09-13 Ortho-Mcneil Pharmaceutical, Inc. Resilient transdermal drug-delivery device and compositions and devices employing fatty acid esters/ethers of alkanediols and percutaneous absorption enhancers
US4900555A (en) * 1987-02-26 1990-02-13 Alza Corporation Skin permeation enhancer compositions using sucrose esters
US4746515A (en) * 1987-02-26 1988-05-24 Alza Corporation Skin permeation enhancer compositions using glycerol monolaurate
CH674618A5 (enrdf_load_stackoverflow) * 1987-04-02 1990-06-29 Ciba Geigy Ag
US4783450A (en) * 1987-04-13 1988-11-08 Warner-Lambert Company Use of commercial lecithin as skin penetration enhancer
US4764379A (en) * 1987-08-24 1988-08-16 Alza Corporation Transdermal drug delivery device with dual permeation enhancers
US5019395A (en) * 1988-03-08 1991-05-28 Warner-Lambert Company Compositions with enhanced penetration
US4973468A (en) * 1989-03-22 1990-11-27 Cygnus Research Corporation Skin permeation enhancer compositions
US5225198A (en) * 1991-08-27 1993-07-06 Cygnus Therapeutic Systems Transdermal administration of short or intermediate half-life benzodiazepines
BR9200386A (pt) * 1992-01-30 1992-07-07 Giuseppe Betti Emulsao veicular basica

Also Published As

Publication number Publication date
CA2126214A1 (en) 1993-07-08
EP0617600A1 (en) 1994-10-05
AU3247293A (en) 1993-07-28
JPH07506562A (ja) 1995-07-20
US5229130A (en) 1993-07-20
EP0617600A4 (en) 1995-06-14
WO1993012744A1 (en) 1993-07-08
TW262385B (enrdf_load_stackoverflow) 1995-11-11

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