JP2698870B2 - シクロスポリンの投与による腎毒性の軽減剤 - Google Patents

シクロスポリンの投与による腎毒性の軽減剤

Info

Publication number
JP2698870B2
JP2698870B2 JP62273746A JP27374687A JP2698870B2 JP 2698870 B2 JP2698870 B2 JP 2698870B2 JP 62273746 A JP62273746 A JP 62273746A JP 27374687 A JP27374687 A JP 27374687A JP 2698870 B2 JP2698870 B2 JP 2698870B2
Authority
JP
Japan
Prior art keywords
group
cyclosporine
administration
compound
agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
JP62273746A
Other languages
English (en)
Japanese (ja)
Other versions
JPH01117834A (ja
Inventor
紀博 柿本
和雄 熊野
國衛 中村
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asai Germanium Research Institute Co Ltd
Original Assignee
Asai Germanium Research Institute Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asai Germanium Research Institute Co Ltd filed Critical Asai Germanium Research Institute Co Ltd
Priority to JP62273746A priority Critical patent/JP2698870B2/ja
Priority to CA000580729A priority patent/CA1314211C/en
Priority to US07/261,406 priority patent/US4919917A/en
Priority to FR888814058A priority patent/FR2622446B1/fr
Priority to DE3836652A priority patent/DE3836652A1/de
Priority to GB8825170A priority patent/GB2211410B/en
Publication of JPH01117834A publication Critical patent/JPH01117834A/ja
Application granted granted Critical
Publication of JP2698870B2 publication Critical patent/JP2698870B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/30—Germanium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP62273746A 1987-10-29 1987-10-29 シクロスポリンの投与による腎毒性の軽減剤 Expired - Fee Related JP2698870B2 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP62273746A JP2698870B2 (ja) 1987-10-29 1987-10-29 シクロスポリンの投与による腎毒性の軽減剤
CA000580729A CA1314211C (en) 1987-10-29 1988-10-20 Agent for reducing nephrotoxicity caused by cyclosporin administration
US07/261,406 US4919917A (en) 1987-10-29 1988-10-24 Agent for reducing nephrotoxicity caused by cyclosporin administration
FR888814058A FR2622446B1 (fr) 1987-10-29 1988-10-27 Agent pour reduire la nephrotoxicite produite par l'administration de cyclosporine
DE3836652A DE3836652A1 (de) 1987-10-29 1988-10-27 Mittel zur verringerung der durch verabreichung von ciclosporin verursachten nierenschaedigung
GB8825170A GB2211410B (en) 1987-10-29 1988-10-27 Organogermanium compounds for reducing the nephrotoxicity caused by cyclosporin administration

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62273746A JP2698870B2 (ja) 1987-10-29 1987-10-29 シクロスポリンの投与による腎毒性の軽減剤

Publications (2)

Publication Number Publication Date
JPH01117834A JPH01117834A (ja) 1989-05-10
JP2698870B2 true JP2698870B2 (ja) 1998-01-19

Family

ID=17531994

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62273746A Expired - Fee Related JP2698870B2 (ja) 1987-10-29 1987-10-29 シクロスポリンの投与による腎毒性の軽減剤

Country Status (6)

Country Link
US (1) US4919917A (OSRAM)
JP (1) JP2698870B2 (OSRAM)
CA (1) CA1314211C (OSRAM)
DE (1) DE3836652A1 (OSRAM)
FR (1) FR2622446B1 (OSRAM)
GB (1) GB2211410B (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01149723A (ja) * 1987-12-07 1989-06-12 Asai Gerumaniumu Kenkyusho:Kk 骨芽細胞活性化剤
AU635045B2 (en) * 1989-07-20 1993-03-11 Asai Germanium Research Institute Co., Ltd Agent for preventing and treating opacity of lens
US5010092A (en) * 1989-12-22 1991-04-23 Wisconsin Alumni Research Foundation Protection against chemically-induced kidney damage by methimazole
JPH05255130A (ja) * 1992-03-16 1993-10-05 Asai Gerumaniumu Kenkyusho:Kk メイラード反応抑制改善剤
AU3955297A (en) * 1997-03-11 1998-09-29 Kuzmin, Konstantin Kuzmich Process for increasing the therapeutic effect and reducing the toxicity of drugs, metals, and organic and inorganic compounds
DE19750287A1 (de) * 1997-11-13 1998-04-02 Heinz Kiefer Homöopathisches Arzneimittel zur Entgiftung des Körpers von Quecksilber aus Amalgam-Zahnfüllungen
EP1105117A1 (en) * 1998-08-17 2001-06-13 Evgeny Vladimirovich Soloviev Bio-chemical germanium complexes with high therapeutic efficiency and wide application spectrum

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1793288B1 (de) * 1968-03-29 1971-05-27 Daiichi Yakuhin Sangyo Kk Verfahren zur Herstellung von Organogermaniumoxiden
GB1365997A (en) * 1972-05-25 1974-09-04 Asai K Medicament comprising an organo germanium sesquioxide compound
US4271084A (en) * 1978-03-01 1981-06-02 Ryuichi Sato Germanium-containing organic polymer and the process for the production of the same
JPS55122717A (en) * 1979-03-15 1980-09-20 Asai Gerumaniumu Kenkyusho:Kk Interferon inducer
FR2548187B1 (fr) * 1983-07-01 1988-07-15 Asai Germanium Res Inst Composes d'organo-germanium et leurs utilisations therapeutiques en tant qu'inhibiteurs des enzymes qui degradent les peptides opioides
JPS6016924A (ja) * 1983-07-11 1985-01-28 Asai Gerumaniumu Kenkyusho:Kk 抗腫瘍剤
JPS63107920A (ja) * 1986-06-18 1988-05-12 Asai Gerumaniumu Kenkyusho:Kk 骨芽細胞活性化剤

Also Published As

Publication number Publication date
US4919917A (en) 1990-04-24
DE3836652C2 (OSRAM) 1991-08-22
DE3836652A1 (de) 1989-05-11
JPH01117834A (ja) 1989-05-10
FR2622446A1 (fr) 1989-05-05
GB2211410B (en) 1991-06-12
GB2211410A (en) 1989-07-05
CA1314211C (en) 1993-03-09
GB8825170D0 (en) 1988-11-30
FR2622446B1 (fr) 1994-09-02

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