JP2025514382A5 - - Google Patents

Info

Publication number
JP2025514382A5
JP2025514382A5 JP2024563854A JP2024563854A JP2025514382A5 JP 2025514382 A5 JP2025514382 A5 JP 2025514382A5 JP 2024563854 A JP2024563854 A JP 2024563854A JP 2024563854 A JP2024563854 A JP 2024563854A JP 2025514382 A5 JP2025514382 A5 JP 2025514382A5
Authority
JP
Japan
Prior art keywords
alkyl
group
nr11r12
alkynyl
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024563854A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025514382A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2023/054494 external-priority patent/WO2023209692A1/en
Publication of JP2025514382A publication Critical patent/JP2025514382A/ja
Publication of JP2025514382A5 publication Critical patent/JP2025514382A5/ja
Pending legal-status Critical Current

Links

JP2024563854A 2022-04-29 2023-04-29 Rock2の阻害剤 Pending JP2025514382A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263336667P 2022-04-29 2022-04-29
US63/336,667 2022-04-29
PCT/IB2023/054494 WO2023209692A1 (en) 2022-04-29 2023-04-29 Inhibitors of rock2

Publications (2)

Publication Number Publication Date
JP2025514382A JP2025514382A (ja) 2025-05-02
JP2025514382A5 true JP2025514382A5 (enExample) 2026-05-11

Family

ID=86604437

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024563854A Pending JP2025514382A (ja) 2022-04-29 2023-04-29 Rock2の阻害剤

Country Status (9)

Country Link
US (1) US20250289807A1 (enExample)
EP (1) EP4514466A1 (enExample)
JP (1) JP2025514382A (enExample)
KR (1) KR20250019030A (enExample)
CN (1) CN119604496A (enExample)
AU (1) AU2023262720A1 (enExample)
CA (1) CA3250707A1 (enExample)
IL (1) IL316616A (enExample)
WO (1) WO2023209692A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2026502949A (ja) 2022-12-30 2026-01-27 アヴィセンナ バイオサイエンシズ インコーポレイテッド アザインドールrock阻害剤
IL327381A (en) 2023-09-28 2026-05-01 Graviton Pharmaceuticals B V Treatment for type 1 diabetes using ROCK2 and DYRK1 inhibitors
IL327385A (en) 2023-09-29 2026-05-01 Graviton Pharmaceuticals B V ROCK2 inhibitors in the treatment of obesity
WO2026011129A1 (en) * 2024-07-03 2026-01-08 Avicenna Biosciences, Inc. Azaindole rock inhibitors for the treatment of medical disorders
CN120204259B (zh) * 2025-04-17 2025-11-18 江西省肿瘤医院(江西省第二人民医院、江西省癌症中心) Rock2抑制剂及其在制备治疗胆管癌的药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7311228B2 (ja) 2017-06-30 2023-07-19 ベイジン タイド ファーマシューティカル カンパニー リミテッド Rho-関連プロテインキナーゼ阻害剤、それを含む医薬組成物並びにその調製方法及び使用
JP7399848B2 (ja) * 2017-09-01 2023-12-18 カドモン コーポレイション,リミティド ライアビリティ カンパニー Rho関連コイルドコイル含有プロテインキナーゼの阻害剤

Similar Documents

Publication Publication Date Title
JP2023538408A5 (enExample)
JP2024519496A5 (enExample)
CN110582489A (zh) Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
JP2022544714A5 (enExample)
CN110573501A (zh) Rho相关蛋白激酶抑制剂、包含其的药物组合物及其制备方法和用途
JP2019519476A5 (enExample)
JP2022507805A5 (enExample)
JP2022550640A5 (enExample)
JP2024517016A5 (enExample)
JP2022538301A5 (enExample)
JP2024167182A5 (enExample)
JP2020506899A5 (enExample)
JP2019514883A5 (enExample)
JP2018529745A5 (enExample)
JP2020535165A5 (enExample)
JP2018517731A5 (enExample)
JP2024541920A5 (enExample)
JP2011513476A5 (enExample)
JP2021513982A5 (enExample)
JP2022500469A5 (enExample)
JP2023533203A5 (enExample)
JP2019532054A5 (enExample)
JP2024517016A (ja) Lpa受容体アンタゴニスト及びそれらの使用
WO2008117229A4 (en) Muscarinic receptor antagonists
JP2024505571A5 (enExample)