JP2025509347A - 屠殺された動物の廃棄組織からのヘパリンならびに未変性タンパク質およびペプチドの混合物 - Google Patents

屠殺された動物の廃棄組織からのヘパリンならびに未変性タンパク質およびペプチドの混合物 Download PDF

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JP2025509347A
JP2025509347A JP2024553576A JP2024553576A JP2025509347A JP 2025509347 A JP2025509347 A JP 2025509347A JP 2024553576 A JP2024553576 A JP 2024553576A JP 2024553576 A JP2024553576 A JP 2024553576A JP 2025509347 A JP2025509347 A JP 2025509347A
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peptides
proteins
fraction
heparin
steps
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JP2024553576A
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Japanese (ja)
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JP2025509347A5 (https=
Inventor
フェレール，ホセ エスカイチ
ルビオ，パブロ ラミレス
カリノ，ステファノ
ルッソ，カルロス チェトリット
スレダ，ポー サルバテッラ
プイグ，ピラール ダルマウ
サラビア，ジュディス プイグセグール
パルディーリョ，マルク モンテロ
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ホライズン アイピー，エス．エル
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Publication of JP2025509347A publication Critical patent/JP2025509347A/ja
Publication of JP2025509347A5 publication Critical patent/JP2025509347A5/ja
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    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L99/00—Compositions of natural macromolecular compounds or of derivatives thereof not provided for in groups C08L89/00 - C08L97/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/10—Heparin; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C12N2330/10—Production naturally occurring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Water Supply & Treatment (AREA)
  • Materials Engineering (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
JP2024553576A 2022-03-08 2023-03-07 屠殺された動物の廃棄組織からのヘパリンならびに未変性タンパク質およびペプチドの混合物 Pending JP2025509347A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP22382214 2022-03-08
EP22382214.9 2022-03-08
PCT/EP2023/055750 WO2023170064A1 (en) 2022-03-08 2023-03-07 Heparin and mixtures of native proteins and peptides from waste tissue of slaughtered animals

Publications (2)

Publication Number Publication Date
JP2025509347A true JP2025509347A (ja) 2025-04-11
JP2025509347A5 JP2025509347A5 (https=) 2026-03-17

Family

ID=80978811

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Application Number Title Priority Date Filing Date
JP2024553576A Pending JP2025509347A (ja) 2022-03-08 2023-03-07 屠殺された動物の廃棄組織からのヘパリンならびに未変性タンパク質およびペプチドの混合物

Country Status (10)

Country Link
US (1) US20250101140A1 (https=)
EP (1) EP4490233B1 (https=)
JP (1) JP2025509347A (https=)
CN (1) CN118829681A (https=)
CA (1) CA3249882A1 (https=)
CL (1) CL2024002692A1 (https=)
ES (1) ES3041746T3 (https=)
MX (1) MX2024010892A (https=)
PE (1) PE20241999A1 (https=)
WO (1) WO2023170064A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12565541B1 (en) 2025-09-03 2026-03-03 Camelx Biomedical & Research Method for extracting unfractionated heparin from camel intestinal mucosa

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU177887B (en) * 1979-03-21 1982-01-28 Richter Gedeon Vegyeszet Process for preparing a raw material containing heparin
WO2003102132A2 (en) * 2002-04-26 2003-12-11 Genetech, Inc. Non-affinity purification of proteins
CN101182495B (zh) * 2007-11-21 2010-09-22 郑州市通源生物技术有限公司 以猪小肠为原料联产生产碱性磷酸酶和肝素钠的联产工艺
JP6046168B2 (ja) 2012-02-16 2016-12-14 イーライ リリー アンド カンパニー 動物排泄物の環境影響を減少させるための方法および組成物
CN102839162B (zh) 2012-09-26 2016-06-15 西藏天虹科技股份有限责任公司 一种碱性磷酸酶的制取方法
RU2610669C1 (ru) 2015-10-16 2017-02-14 Общество с ограниченной ответственностью "Научно-исследовательский институт средств противоожоговой терапии" Способ получения протеолитического препарата для медицинского применения
CN106035980B (zh) 2016-06-14 2019-06-07 江南大学 一种利用酶解法肝素吸附残液生产肠膜蛋白粉的方法
CN107345207A (zh) * 2017-06-29 2017-11-14 王德亮 用动物肠粘膜生产肠道微生物粉并联产小分子肽、肝素钠、碱性磷酸酶的方法及应用
CN107236059A (zh) 2017-08-10 2017-10-10 如皋市永兴肠衣有限公司 小肠粘膜副产物同步分离提取技术
US20200157161A1 (en) * 2018-11-19 2020-05-21 Gnubiotics Sciences Sa Compositions from gastrointestinal tract mucins and uses thereof
EP3924391A4 (en) * 2019-02-11 2022-10-05 Heptech Pesquisa E Desenvolvimento Ltda SAFE BOVINES HEPARIN, PROCESS OF MANUFACTURE AND USE
CN113999330B (zh) * 2021-12-07 2022-08-19 潢川县鹏升畜产品有限公司 一种低盐浓度肝素钠与活性肠蛋白肽分离联产工艺

Also Published As

Publication number Publication date
EP4490233B1 (en) 2025-05-21
PE20241999A1 (es) 2024-09-27
EP4490233C0 (en) 2025-05-21
CL2024002692A1 (es) 2025-02-07
WO2023170064A1 (en) 2023-09-14
MX2024010892A (es) 2024-09-17
CA3249882A1 (en) 2023-09-14
CN118829681A (zh) 2024-10-22
US20250101140A1 (en) 2025-03-27
EP4490233A1 (en) 2025-01-15
ES3041746T3 (en) 2025-11-14

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