CL2024002692A1 - Heparina y mezclas de proteínas y péptidos nativos procedentes de tejidos de desecho de animales - Google Patents
Heparina y mezclas de proteínas y péptidos nativos procedentes de tejidos de desecho de animalesInfo
- Publication number
- CL2024002692A1 CL2024002692A1 CL2024002692A CL2024002692A CL2024002692A1 CL 2024002692 A1 CL2024002692 A1 CL 2024002692A1 CL 2024002692 A CL2024002692 A CL 2024002692A CL 2024002692 A CL2024002692 A CL 2024002692A CL 2024002692 A1 CL2024002692 A1 CL 2024002692A1
- Authority
- CL
- Chile
- Prior art keywords
- peptides
- heparin
- mixtures
- animal waste
- native proteins
- Prior art date
Links
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 title abstract 2
- 229960002897 heparin Drugs 0.000 title abstract 2
- 229920000669 heparin Polymers 0.000 title abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 239000010828 animal waste Substances 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000284 extract Substances 0.000 abstract 1
- 238000005194 fractionation Methods 0.000 abstract 1
- 210000004347 intestinal mucosa Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L89/00—Compositions of proteins; Compositions of derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L99/00—Compositions of natural macromolecular compounds or of derivatives thereof not provided for in groups C08L89/00 - C08L97/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/10—Heparin; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/10—Production naturally occurring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Water Supply & Treatment (AREA)
- Materials Engineering (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP22382214 | 2022-03-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CL2024002692A1 true CL2024002692A1 (es) | 2025-02-07 |
Family
ID=80978811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CL2024002692A CL2024002692A1 (es) | 2022-03-08 | 2024-09-06 | Heparina y mezclas de proteínas y péptidos nativos procedentes de tejidos de desecho de animales |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20250101140A1 (https=) |
| EP (1) | EP4490233B1 (https=) |
| JP (1) | JP2025509347A (https=) |
| CN (1) | CN118829681A (https=) |
| CA (1) | CA3249882A1 (https=) |
| CL (1) | CL2024002692A1 (https=) |
| ES (1) | ES3041746T3 (https=) |
| MX (1) | MX2024010892A (https=) |
| PE (1) | PE20241999A1 (https=) |
| WO (1) | WO2023170064A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12565541B1 (en) | 2025-09-03 | 2026-03-03 | Camelx Biomedical & Research | Method for extracting unfractionated heparin from camel intestinal mucosa |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU177887B (en) * | 1979-03-21 | 1982-01-28 | Richter Gedeon Vegyeszet | Process for preparing a raw material containing heparin |
| WO2003102132A2 (en) * | 2002-04-26 | 2003-12-11 | Genetech, Inc. | Non-affinity purification of proteins |
| CN101182495B (zh) * | 2007-11-21 | 2010-09-22 | 郑州市通源生物技术有限公司 | 以猪小肠为原料联产生产碱性磷酸酶和肝素钠的联产工艺 |
| JP6046168B2 (ja) | 2012-02-16 | 2016-12-14 | イーライ リリー アンド カンパニー | 動物排泄物の環境影響を減少させるための方法および組成物 |
| CN102839162B (zh) | 2012-09-26 | 2016-06-15 | 西藏天虹科技股份有限责任公司 | 一种碱性磷酸酶的制取方法 |
| RU2610669C1 (ru) | 2015-10-16 | 2017-02-14 | Общество с ограниченной ответственностью "Научно-исследовательский институт средств противоожоговой терапии" | Способ получения протеолитического препарата для медицинского применения |
| CN106035980B (zh) | 2016-06-14 | 2019-06-07 | 江南大学 | 一种利用酶解法肝素吸附残液生产肠膜蛋白粉的方法 |
| CN107345207A (zh) * | 2017-06-29 | 2017-11-14 | 王德亮 | 用动物肠粘膜生产肠道微生物粉并联产小分子肽、肝素钠、碱性磷酸酶的方法及应用 |
| CN107236059A (zh) | 2017-08-10 | 2017-10-10 | 如皋市永兴肠衣有限公司 | 小肠粘膜副产物同步分离提取技术 |
| US20200157161A1 (en) * | 2018-11-19 | 2020-05-21 | Gnubiotics Sciences Sa | Compositions from gastrointestinal tract mucins and uses thereof |
| EP3924391A4 (en) * | 2019-02-11 | 2022-10-05 | Heptech Pesquisa E Desenvolvimento Ltda | SAFE BOVINES HEPARIN, PROCESS OF MANUFACTURE AND USE |
| CN113999330B (zh) * | 2021-12-07 | 2022-08-19 | 潢川县鹏升畜产品有限公司 | 一种低盐浓度肝素钠与活性肠蛋白肽分离联产工艺 |
-
2023
- 2023-03-07 ES ES23708519T patent/ES3041746T3/es active Active
- 2023-03-07 CA CA3249882A patent/CA3249882A1/en active Pending
- 2023-03-07 US US18/842,220 patent/US20250101140A1/en active Pending
- 2023-03-07 MX MX2024010892A patent/MX2024010892A/es unknown
- 2023-03-07 EP EP23708519.6A patent/EP4490233B1/en active Active
- 2023-03-07 WO PCT/EP2023/055750 patent/WO2023170064A1/en not_active Ceased
- 2023-03-07 CN CN202380026054.2A patent/CN118829681A/zh active Pending
- 2023-03-07 JP JP2024553576A patent/JP2025509347A/ja active Pending
- 2023-03-07 PE PE2024001831A patent/PE20241999A1/es unknown
-
2024
- 2024-09-06 CL CL2024002692A patent/CL2024002692A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP4490233B1 (en) | 2025-05-21 |
| PE20241999A1 (es) | 2024-09-27 |
| EP4490233C0 (en) | 2025-05-21 |
| WO2023170064A1 (en) | 2023-09-14 |
| MX2024010892A (es) | 2024-09-17 |
| CA3249882A1 (en) | 2023-09-14 |
| CN118829681A (zh) | 2024-10-22 |
| US20250101140A1 (en) | 2025-03-27 |
| EP4490233A1 (en) | 2025-01-15 |
| JP2025509347A (ja) | 2025-04-11 |
| ES3041746T3 (en) | 2025-11-14 |
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