ES3041746T3 - Heparin and mixtures of native proteins and peptides from waste tissue of slaughtered animals - Google Patents

Heparin and mixtures of native proteins and peptides from waste tissue of slaughtered animals

Info

Publication number
ES3041746T3
ES3041746T3 ES23708519T ES23708519T ES3041746T3 ES 3041746 T3 ES3041746 T3 ES 3041746T3 ES 23708519 T ES23708519 T ES 23708519T ES 23708519 T ES23708519 T ES 23708519T ES 3041746 T3 ES3041746 T3 ES 3041746T3
Authority
ES
Spain
Prior art keywords
proteins
peptides
fraction
heparin
mucosa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES23708519T
Other languages
English (en)
Spanish (es)
Inventor
Ferrer José Escaich
Rubio Pablo Ramirez
Stefano Carlino
Russo Carlos Chetrit
Sureda Pau Salvatella
Puig Pilar Dalmau
Sarabia Judith Puigsegur
Pardillo Marc Montero
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Horizon Ip S L
Original Assignee
Horizon Ip S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Horizon Ip S L filed Critical Horizon Ip S L
Application granted granted Critical
Publication of ES3041746T3 publication Critical patent/ES3041746T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00—Compositions of proteins; Compositions of derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L99/00—Compositions of natural macromolecular compounds or of derivatives thereof not provided for in groups C08L89/00 - C08L97/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/10—Heparin; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C12N2330/10—Production naturally occurring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Water Supply & Treatment (AREA)
  • Materials Engineering (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
ES23708519T 2022-03-08 2023-03-07 Heparin and mixtures of native proteins and peptides from waste tissue of slaughtered animals Active ES3041746T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP22382214 2022-03-08
PCT/EP2023/055750 WO2023170064A1 (en) 2022-03-08 2023-03-07 Heparin and mixtures of native proteins and peptides from waste tissue of slaughtered animals

Publications (1)

Publication Number Publication Date
ES3041746T3 true ES3041746T3 (en) 2025-11-14

Family

ID=80978811

Family Applications (1)

Application Number Title Priority Date Filing Date
ES23708519T Active ES3041746T3 (en) 2022-03-08 2023-03-07 Heparin and mixtures of native proteins and peptides from waste tissue of slaughtered animals

Country Status (10)

Country Link
US (1) US20250101140A1 (https=)
EP (1) EP4490233B1 (https=)
JP (1) JP2025509347A (https=)
CN (1) CN118829681A (https=)
CA (1) CA3249882A1 (https=)
CL (1) CL2024002692A1 (https=)
ES (1) ES3041746T3 (https=)
MX (1) MX2024010892A (https=)
PE (1) PE20241999A1 (https=)
WO (1) WO2023170064A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12565541B1 (en) 2025-09-03 2026-03-03 Camelx Biomedical & Research Method for extracting unfractionated heparin from camel intestinal mucosa

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU177887B (en) * 1979-03-21 1982-01-28 Richter Gedeon Vegyeszet Process for preparing a raw material containing heparin
WO2003102132A2 (en) * 2002-04-26 2003-12-11 Genetech, Inc. Non-affinity purification of proteins
CN101182495B (zh) * 2007-11-21 2010-09-22 郑州市通源生物技术有限公司 以猪小肠为原料联产生产碱性磷酸酶和肝素钠的联产工艺
JP6046168B2 (ja) 2012-02-16 2016-12-14 イーライ リリー アンド カンパニー 動物排泄物の環境影響を減少させるための方法および組成物
CN102839162B (zh) 2012-09-26 2016-06-15 西藏天虹科技股份有限责任公司 一种碱性磷酸酶的制取方法
RU2610669C1 (ru) 2015-10-16 2017-02-14 Общество с ограниченной ответственностью "Научно-исследовательский институт средств противоожоговой терапии" Способ получения протеолитического препарата для медицинского применения
CN106035980B (zh) 2016-06-14 2019-06-07 江南大学 一种利用酶解法肝素吸附残液生产肠膜蛋白粉的方法
CN107345207A (zh) * 2017-06-29 2017-11-14 王德亮 用动物肠粘膜生产肠道微生物粉并联产小分子肽、肝素钠、碱性磷酸酶的方法及应用
CN107236059A (zh) 2017-08-10 2017-10-10 如皋市永兴肠衣有限公司 小肠粘膜副产物同步分离提取技术
US20200157161A1 (en) * 2018-11-19 2020-05-21 Gnubiotics Sciences Sa Compositions from gastrointestinal tract mucins and uses thereof
EP3924391A4 (en) * 2019-02-11 2022-10-05 Heptech Pesquisa E Desenvolvimento Ltda SAFE BOVINES HEPARIN, PROCESS OF MANUFACTURE AND USE
CN113999330B (zh) * 2021-12-07 2022-08-19 潢川县鹏升畜产品有限公司 一种低盐浓度肝素钠与活性肠蛋白肽分离联产工艺

Also Published As

Publication number Publication date
EP4490233B1 (en) 2025-05-21
PE20241999A1 (es) 2024-09-27
EP4490233C0 (en) 2025-05-21
CL2024002692A1 (es) 2025-02-07
WO2023170064A1 (en) 2023-09-14
MX2024010892A (es) 2024-09-17
CA3249882A1 (en) 2023-09-14
CN118829681A (zh) 2024-10-22
US20250101140A1 (en) 2025-03-27
EP4490233A1 (en) 2025-01-15
JP2025509347A (ja) 2025-04-11

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