PE20241999A1 - Heparina y mezclas de proteinas y peptidos nativos procedentes de tejidos de desecho de animales sacrificados - Google Patents

Heparina y mezclas de proteinas y peptidos nativos procedentes de tejidos de desecho de animales sacrificados

Info

Publication number
PE20241999A1
PE20241999A1 PE2024001831A PE2024001831A PE20241999A1 PE 20241999 A1 PE20241999 A1 PE 20241999A1 PE 2024001831 A PE2024001831 A PE 2024001831A PE 2024001831 A PE2024001831 A PE 2024001831A PE 20241999 A1 PE20241999 A1 PE 20241999A1
Authority
PE
Peru
Prior art keywords
peptides
heparin
mixtures
native proteins
sacrificed animals
Prior art date
Application number
PE2024001831A
Other languages
English (en)
Spanish (es)
Inventor
Rubio Pablo Ramirez
Stefano Carlino
Russo Carlos Chetrit
Sureda Pau Salvatella
Puig Pilar Dalmau
Sarabia Judith Puigsegur
Pardillo Marc Montero
Ferrer Jose Escaich
Original Assignee
Horizon Ip S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Horizon Ip S L filed Critical Horizon Ip S L
Publication of PE20241999A1 publication Critical patent/PE20241999A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/18Ion-exchange chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/34Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L89/00Compositions of proteins; Compositions of derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L99/00Compositions of natural macromolecular compounds or of derivatives thereof not provided for in groups C08L89/00 - C08L97/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/10Heparin; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00Production
    • C12N2330/10Production naturally occurring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Water Supply & Treatment (AREA)
  • Materials Engineering (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
PE2024001831A 2022-03-08 2023-03-07 Heparina y mezclas de proteinas y peptidos nativos procedentes de tejidos de desecho de animales sacrificados PE20241999A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP22382214 2022-03-08
PCT/EP2023/055750 WO2023170064A1 (en) 2022-03-08 2023-03-07 Heparin and mixtures of native proteins and peptides from waste tissue of slaughtered animals

Publications (1)

Publication Number Publication Date
PE20241999A1 true PE20241999A1 (es) 2024-09-27

Family

ID=80978811

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2024001831A PE20241999A1 (es) 2022-03-08 2023-03-07 Heparina y mezclas de proteinas y peptidos nativos procedentes de tejidos de desecho de animales sacrificados

Country Status (10)

Country Link
US (1) US20250101140A1 (https=)
EP (1) EP4490233B1 (https=)
JP (1) JP2025509347A (https=)
CN (1) CN118829681A (https=)
CA (1) CA3249882A1 (https=)
CL (1) CL2024002692A1 (https=)
ES (1) ES3041746T3 (https=)
MX (1) MX2024010892A (https=)
PE (1) PE20241999A1 (https=)
WO (1) WO2023170064A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12565541B1 (en) 2025-09-03 2026-03-03 Camelx Biomedical & Research Method for extracting unfractionated heparin from camel intestinal mucosa

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU177887B (en) * 1979-03-21 1982-01-28 Richter Gedeon Vegyeszet Process for preparing a raw material containing heparin
WO2003102132A2 (en) * 2002-04-26 2003-12-11 Genetech, Inc. Non-affinity purification of proteins
CN101182495B (zh) * 2007-11-21 2010-09-22 郑州市通源生物技术有限公司 以猪小肠为原料联产生产碱性磷酸酶和肝素钠的联产工艺
JP6046168B2 (ja) 2012-02-16 2016-12-14 イーライ リリー アンド カンパニー 動物排泄物の環境影響を減少させるための方法および組成物
CN102839162B (zh) 2012-09-26 2016-06-15 西藏天虹科技股份有限责任公司 一种碱性磷酸酶的制取方法
RU2610669C1 (ru) 2015-10-16 2017-02-14 Общество с ограниченной ответственностью "Научно-исследовательский институт средств противоожоговой терапии" Способ получения протеолитического препарата для медицинского применения
CN106035980B (zh) 2016-06-14 2019-06-07 江南大学 一种利用酶解法肝素吸附残液生产肠膜蛋白粉的方法
CN107345207A (zh) * 2017-06-29 2017-11-14 王德亮 用动物肠粘膜生产肠道微生物粉并联产小分子肽、肝素钠、碱性磷酸酶的方法及应用
CN107236059A (zh) 2017-08-10 2017-10-10 如皋市永兴肠衣有限公司 小肠粘膜副产物同步分离提取技术
US20200157161A1 (en) * 2018-11-19 2020-05-21 Gnubiotics Sciences Sa Compositions from gastrointestinal tract mucins and uses thereof
EP3924391A4 (en) * 2019-02-11 2022-10-05 Heptech Pesquisa E Desenvolvimento Ltda SAFE BOVINES HEPARIN, PROCESS OF MANUFACTURE AND USE
CN113999330B (zh) * 2021-12-07 2022-08-19 潢川县鹏升畜产品有限公司 一种低盐浓度肝素钠与活性肠蛋白肽分离联产工艺

Also Published As

Publication number Publication date
EP4490233B1 (en) 2025-05-21
EP4490233C0 (en) 2025-05-21
CL2024002692A1 (es) 2025-02-07
WO2023170064A1 (en) 2023-09-14
MX2024010892A (es) 2024-09-17
CA3249882A1 (en) 2023-09-14
CN118829681A (zh) 2024-10-22
US20250101140A1 (en) 2025-03-27
EP4490233A1 (en) 2025-01-15
JP2025509347A (ja) 2025-04-11
ES3041746T3 (en) 2025-11-14

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