JP2025508542A5 - - Google Patents
Info
- Publication number
- JP2025508542A5 JP2025508542A5 JP2024552725A JP2024552725A JP2025508542A5 JP 2025508542 A5 JP2025508542 A5 JP 2025508542A5 JP 2024552725 A JP2024552725 A JP 2024552725A JP 2024552725 A JP2024552725 A JP 2024552725A JP 2025508542 A5 JP2025508542 A5 JP 2025508542A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- pharmaceutically acceptable
- acceptable salt
- compound according
- halo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202263317740P | 2022-03-08 | 2022-03-08 | |
| US63/317,740 | 2022-03-08 | ||
| PCT/US2023/063643 WO2023172845A1 (en) | 2022-03-08 | 2023-03-03 | Pparg inverse agonists and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025508542A JP2025508542A (ja) | 2025-03-26 |
| JP2025508542A5 true JP2025508542A5 (https=) | 2026-03-06 |
Family
ID=86006834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024552725A Pending JP2025508542A (ja) | 2022-03-08 | 2023-03-03 | Ｐｐａｒｇインバースアゴニストおよびそれらの使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20250186425A1 (https=) |
| EP (1) | EP4490147A1 (https=) |
| JP (1) | JP2025508542A (https=) |
| CN (1) | CN118984823A (https=) |
| AU (1) | AU2023231613A1 (https=) |
| CA (1) | CA3254011A1 (https=) |
| WO (1) | WO2023172845A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3254026A1 (en) * | 2022-03-08 | 2023-09-14 | Flare Therapeutics Inc. | Inverse PPARG agonists and their uses |
| WO2025098515A1 (en) * | 2023-11-10 | 2025-05-15 | Danatlas Pharmaceuticals Co., Ltd. | Heterocyclic derivatives, compositions and uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001083427A1 (en) * | 2000-04-28 | 2001-11-08 | Sankyo Company, Limited | PPARη MODULATORS |
| AU2006223000B2 (en) * | 2005-03-14 | 2011-06-30 | Center For Molecular Medicine And Immunology | Methods of treating cancer using PPAR-gamma antagonists |
| CZ300589B6 (cs) * | 2006-09-04 | 2009-06-24 | Univerzita Palackého | Deriváty 2-fenyl-3-hydroxychinolin-4(1H)-onu a zpusob jejich prípravy a použití |
| CN105982884B (zh) * | 2015-02-25 | 2019-05-24 | 上海中医药大学 | 一种补骨脂二氢黄酮甲醚及其类似物的用途 |
| CN107661333B (zh) * | 2016-07-27 | 2020-12-29 | 清华大学 | 化合物在治疗肺癌中的应用 |
| CN107522657B (zh) * | 2017-09-28 | 2020-06-26 | 上海中医药大学 | 一种具有ppar多重激动活性的化合物及其制备方法和应用 |
| EP3498694A1 (en) * | 2017-12-12 | 2019-06-19 | Medibiofarma, S.L. | New benzamide derivatives as ppar-gamma modulators |
| CN117616012A (zh) * | 2021-03-02 | 2024-02-27 | 弗拉雷治疗公司 | Pparg反向激动剂及其用途 |
| CA3227603A1 (en) * | 2021-08-05 | 2023-02-09 | Jonathan E. Wilson | Pparg inverse agonists and uses thereof |
-
2023
- 2023-03-03 EP EP23716983.4A patent/EP4490147A1/en active Pending
- 2023-03-03 WO PCT/US2023/063643 patent/WO2023172845A1/en not_active Ceased
- 2023-03-03 JP JP2024552725A patent/JP2025508542A/ja active Pending
- 2023-03-03 CN CN202380033175.XA patent/CN118984823A/zh active Pending
- 2023-03-03 AU AU2023231613A patent/AU2023231613A1/en active Pending
- 2023-03-03 CA CA3254011A patent/CA3254011A1/en active Pending
- 2023-03-03 US US18/844,419 patent/US20250186425A1/en active Pending
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