JP2024513494A5 - - Google Patents
Info
- Publication number
- JP2024513494A5 JP2024513494A5 JP2023561863A JP2023561863A JP2024513494A5 JP 2024513494 A5 JP2024513494 A5 JP 2024513494A5 JP 2023561863 A JP2023561863 A JP 2023561863A JP 2023561863 A JP2023561863 A JP 2023561863A JP 2024513494 A5 JP2024513494 A5 JP 2024513494A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cancer
- alkoxy
- pharmaceutical composition
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163172643P | 2021-04-08 | 2021-04-08 | |
| US63/172,643 | 2021-04-08 | ||
| US202163253029P | 2021-10-06 | 2021-10-06 | |
| US63/253,029 | 2021-10-06 | ||
| PCT/US2022/023388 WO2022216645A1 (en) | 2021-04-08 | 2022-04-05 | Combination therapies using prmt5 inhibitors for the treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024513494A JP2024513494A (ja) | 2024-03-25 |
| JP2024513494A5 true JP2024513494A5 (https=) | 2025-04-14 |
Family
ID=81748438
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023561863A Pending JP2024513494A (ja) | 2021-04-08 | 2022-04-05 | がんの治療のためのｐｒｍｔ５阻害剤を使用する併用療法 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US12171765B2 (https=) |
| EP (1) | EP4319753A1 (https=) |
| JP (1) | JP2024513494A (https=) |
| KR (1) | KR20230167050A (https=) |
| AU (1) | AU2022254651A1 (https=) |
| CA (1) | CA3214535A1 (https=) |
| IL (1) | IL307393A (https=) |
| MX (1) | MX2023011853A (https=) |
| WO (1) | WO2022216645A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20240208912A1 (en) * | 2021-03-11 | 2024-06-27 | Mirati Therapeutics, Inc. | MTA-Cooperative PRMT5 Inhibitors |
| WO2023098439A1 (zh) * | 2021-11-30 | 2023-06-08 | 上海和誉生物医药科技有限公司 | 一种吡唑衍生物，其制备方法和在药学上的应用 |
| WO2023125540A1 (zh) * | 2021-12-27 | 2023-07-06 | 南京明德新药研发有限公司 | 吡唑-1(2h)-酞嗪酮类化合物及其应用 |
| CN119301101A (zh) * | 2022-07-29 | 2025-01-10 | 四川科伦博泰生物医药股份有限公司 | 甲基吡唑化合物、包含其的药物组合物及其制备方法和用途 |
| WO2024027703A1 (zh) * | 2022-08-02 | 2024-02-08 | 上海艾力斯医药科技股份有限公司 | 一种prmt5抑制剂、其制备方法及应用 |
| CN120265615A (zh) * | 2022-11-29 | 2025-07-04 | 正大天晴药业集团股份有限公司 | 含有二氢酞嗪的化合物 |
| WO2024177416A1 (ko) * | 2023-02-22 | 2024-08-29 | 단국대학교 천안캠퍼스 산학협력단 | Egfr 표적치료제 내성암 치료용 약학 조성물 |
| WO2025137640A1 (en) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
| WO2025157288A1 (zh) * | 2024-01-26 | 2025-07-31 | 上海湃隆生物科技有限公司 | 包含prmt5抑制剂和cdk4/6抑制剂的药物组合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3268044A2 (en) * | 2015-03-11 | 2018-01-17 | The Broad Institute Inc. | Prmt5 inhibitors for the treatment of cancer with reduced mtap activty |
| JP2021176819A (ja) | 2018-07-31 | 2021-11-11 | アステラス製薬株式会社 | キナゾリン化合物を有効成分とする医薬組成物 |
| IL290341B2 (en) | 2019-09-12 | 2024-11-01 | Mirati Therapeutics Inc | Mta-cooperative prmt5 inhibitors |
| KR20220086628A (ko) * | 2019-10-22 | 2022-06-23 | 루핀 리미티드 | Prmt5 저해제의 약학적 조합물 |
-
2022
- 2022-04-05 EP EP22724161.9A patent/EP4319753A1/en active Pending
- 2022-04-05 CA CA3214535A patent/CA3214535A1/en active Pending
- 2022-04-05 IL IL307393A patent/IL307393A/en unknown
- 2022-04-05 AU AU2022254651A patent/AU2022254651A1/en active Pending
- 2022-04-05 WO PCT/US2022/023388 patent/WO2022216645A1/en not_active Ceased
- 2022-04-05 KR KR1020237035696A patent/KR20230167050A/ko active Pending
- 2022-04-05 JP JP2023561863A patent/JP2024513494A/ja active Pending
- 2022-04-05 MX MX2023011853A patent/MX2023011853A/es unknown
- 2022-04-05 US US17/713,455 patent/US12171765B2/en active Active
-
2024
- 2024-11-19 US US18/951,832 patent/US20250073241A1/en active Pending
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