JP2025506357A5 - - Google Patents

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Publication number
JP2025506357A5
JP2025506357A5 JP2024544690A JP2024544690A JP2025506357A5 JP 2025506357 A5 JP2025506357 A5 JP 2025506357A5 JP 2024544690 A JP2024544690 A JP 2024544690A JP 2024544690 A JP2024544690 A JP 2024544690A JP 2025506357 A5 JP2025506357 A5 JP 2025506357A5
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JP
Japan
Prior art keywords
alkyl
hydrogen
antibody
cide
conjugate according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024544690A
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English (en)
Japanese (ja)
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JP2025506357A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2023/061216 external-priority patent/WO2023147328A1/en
Publication of JP2025506357A publication Critical patent/JP2025506357A/ja
Publication of JP2025506357A5 publication Critical patent/JP2025506357A5/ja
Pending legal-status Critical Current

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JP2024544690A 2022-01-26 2023-01-25 加水分解性マレイミドリンカーを有する抗体コンジュゲート化化学的分解誘導剤及びその方法 Pending JP2025506357A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263303447P 2022-01-26 2022-01-26
US63/303,447 2022-01-26
PCT/US2023/061216 WO2023147328A1 (en) 2022-01-26 2023-01-25 Antibody-conjugated chemical inducers of degradation with hydolysable maleimide linkers and methods thereof

Publications (2)

Publication Number Publication Date
JP2025506357A JP2025506357A (ja) 2025-03-11
JP2025506357A5 true JP2025506357A5 (enExample) 2026-02-02

Family

ID=85477901

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024544690A Pending JP2025506357A (ja) 2022-01-26 2023-01-25 加水分解性マレイミドリンカーを有する抗体コンジュゲート化化学的分解誘導剤及びその方法

Country Status (7)

Country Link
US (1) US20250064968A1 (enExample)
EP (1) EP4469090A1 (enExample)
JP (1) JP2025506357A (enExample)
CN (1) CN118591393A (enExample)
AR (1) AR128330A1 (enExample)
TW (1) TW202340146A (enExample)
WO (1) WO2023147328A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026090411A1 (en) * 2024-10-23 2026-04-30 Prelude Therapeutics Incorporated Brm and brg1 targeting compounds and associated methods of use
WO2026145631A1 (zh) * 2024-12-31 2026-07-09 上海复宏汉霖生物技术股份有限公司 一种配体-药物偶联物及制备方法和应用

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