JP2025503451A5 - - Google Patents

Info

Publication number
JP2025503451A5
JP2025503451A5 JP2024536171A JP2024536171A JP2025503451A5 JP 2025503451 A5 JP2025503451 A5 JP 2025503451A5 JP 2024536171 A JP2024536171 A JP 2024536171A JP 2024536171 A JP2024536171 A JP 2024536171A JP 2025503451 A5 JP2025503451 A5 JP 2025503451A5
Authority
JP
Japan
Prior art keywords
group
amino
amino acid
acid
residue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024536171A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025503451A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/086632 external-priority patent/WO2023111350A2/en
Publication of JP2025503451A publication Critical patent/JP2025503451A/ja
Publication of JP2025503451A5 publication Critical patent/JP2025503451A5/ja
Pending legal-status Critical Current

Links

JP2024536171A 2021-12-17 2022-12-19 炭酸脱水酵素ｉｘリガンド Pending JP2025503451A (ja)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
EPPCT/EP2021/086592 2021-12-17
EP2021086592 2021-12-17
EP2022054857 2022-02-25
EPPCT/EP2022/054857 2022-02-25
EP2022057170 2022-03-18
EPPCT/EP2022/057170 2022-03-18
EP2022057840 2022-03-24
EPPCT/EP2022/057840 2022-03-24
EPPCT/EP2022/067424 2022-06-24
EP2022067424 2022-06-24
EPPCT/EP2022/079606 2022-10-24
EP2022079606 2022-10-24
EPPCT/EP2022/081674 2022-11-11
EP2022081674 2022-11-11
PCT/EP2022/086632 WO2023111350A2 (en) 2021-12-17 2022-12-19 Carbonic anhydrase ix ligands

Publications (2)

Publication Number Publication Date
JP2025503451A JP2025503451A (ja) 2025-02-04
JP2025503451A5 true JP2025503451A5 (enExample) 2025-12-16

Family

ID=84981172

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024536171A Pending JP2025503451A (ja) 2021-12-17 2022-12-19 炭酸脱水酵素ｉｘリガンド

Country Status (13)

Country Link
US (1) US20250339569A1 (enExample)
EP (1) EP4448544A2 (enExample)
JP (1) JP2025503451A (enExample)
KR (1) KR20240133798A (enExample)
AR (1) AR128023A1 (enExample)
AU (1) AU2022410422B2 (enExample)
CA (1) CA3242384A1 (enExample)
CL (1) CL2024001830A1 (enExample)
IL (1) IL313536A (enExample)
MA (1) MA66591A1 (enExample)
MX (1) MX2024007454A (enExample)
TW (1) TW202340226A (enExample)
WO (1) WO2023111350A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4321526A4 (en) * 2022-02-11 2026-04-15 C Biomex Co Ltd Peptide ligand targeting carbonic anhydrase IX, peptide construction comprising it, and associated uses
JP2026522427A (ja) * 2023-06-20 2026-07-07 デバイオファーム インターナショナル エス．エー． 炭酸脱水酵素ｉｘ陽性疾患の治療方法で用いるための放射性標識化合物
AU2024298898A1 (en) * 2023-07-25 2025-11-27 C-Biomex Co., Ltd. Peptide structure targeting carbonic dehydrogenase ix and use thereof
WO2026125277A1 (en) * 2024-12-09 2026-06-18 Debiopharm International S.A. Combination of carbonic anhydrase ix ligands
CN120943901A (zh) * 2025-05-29 2025-11-14 北京肿瘤医院(北京大学肿瘤医院) 经修饰的caix靶向环肽、核素标记物及其在肿瘤诊疗方面的应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4885363A (en) 1987-04-24 1989-12-05 E. R. Squibb & Sons, Inc. 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
US5021556A (en) 1987-07-22 1991-06-04 Neorx Corporation Method of radiolabeling chelating compounds comprising sulfur atoms with metal radionuclides
US5075099A (en) 1988-05-31 1991-12-24 Neorx Corporation Metal radionuclide chelating compounds for improved chelation kinetics
US5364613A (en) 1989-04-07 1994-11-15 Sieving Paul F Polychelants containing macrocyclic chelant moieties
US5367080A (en) 1990-11-08 1994-11-22 Sterling Winthrop Inc. Complexing agents and targeting radioactive immunoreagents useful in therapeutic and diagnostic imaging compositions and methods
US5965107A (en) 1992-03-13 1999-10-12 Diatide, Inc. Technetium-99m labeled peptides for imaging
US6214345B1 (en) 1993-05-14 2001-04-10 Bristol-Myers Squibb Co. Lysosomal enzyme-cleavable antitumor drug conjugates
US5886142A (en) 1997-05-20 1999-03-23 Thomas Jefferson University Radiolabeled thrombus imaging agents
ES2605443T3 (es) 2003-11-06 2017-03-14 Seattle Genetics, Inc. Conjugados de auristatina con anticuerpos anti-HER2 o anti-CD22 y su uso en terapia
EP2100900A1 (en) 2008-03-07 2009-09-16 Universitätsspital Basel Bombesin analog peptide antagonist conjugates
WO2012016713A1 (en) 2010-08-05 2012-02-09 Ruprecht-Karls-Universität Heidelberg Tumour targeting with polypeptides
US9238676B2 (en) * 2012-05-17 2016-01-19 Ra Pharmaceuticals, Inc. Peptide and peptidomimetic inhibitors
EP3442991A4 (en) * 2016-04-15 2019-11-20 RA Pharmaceuticals, Inc. RAS-BINDING PEPTIDES AND METHODS OF USE
TW201919682A (zh) * 2017-08-08 2019-06-01 西班牙商阿爾米雷爾有限公司 活化Ｎｒｆ２路徑的新穎化合物
CA3082271A1 (en) 2017-11-14 2019-05-23 Debiopharm Research & Manufacturing S.A. Ligand-drug-conjugates as substrates for selective cleavage by the exopeptidase activity of cathepsin b
WO2020084305A1 (en) 2018-10-23 2020-04-30 Bicycletx Limited Bicyclic peptide ligands and uses thereof
GB201900525D0 (en) * 2019-01-15 2019-03-06 Bicycletx Ltd Bicyclic peptide ligands specific for caix
GB201900526D0 (en) 2019-01-15 2019-03-06 Bicyclerd Ltd Bicyclic peptide ligands specific for caix
CN118955620A (zh) * 2019-07-08 2024-11-15 3B制药有限公司 包含成纤维细胞活化蛋白配体的化合物及其用途
TWI765195B (zh) 2019-11-22 2022-05-21 行政院原子能委員會核能研究所 雙靶向碳酸酐酶第九型複合物及其造影劑

Similar Documents

Publication Publication Date Title
IL289673B1 (en) Compounds comprising a fibroblast activation protein ligand and use thereof
JP2024503635A5 (enExample)
FI101938B (fi) Polypeptidijohdannaisia
JP2024503637A5 (enExample)
JP7195665B2 (ja) 診断及び治療のための、改善された薬物動態及びコレシストキニン－２受容体（ｃｃｋ２ｒ）への標的化
BR112019012623A2 (pt) ligantes peptídicos para ligação a mt1-mmp
EP3783016A1 (en) Modified antibody and radioactive metal-labelled antibody
NO334093B1 (no) Forbedrede chelatdannerkonjugater, radioaktive metallkomplekser, radiofarmasøytika, sett for fremstilling av radiofarmasøytika, samt bifunksjonelle chelatdannere og fremgangsmåter for fremstilling av slike
MX2013001939A (es) Composiciones de radiorastreador de peptido.
JP2019206533A (ja) 放射性トレーサー組成物及び方法
US20210330824A1 (en) Purification method and compositions
ES2651334T3 (es) Péptidos marcados con tecnecio
Maina et al. [99mTc] Demotensin 5 and 6 in the NTS1-R-targeted imaging of tumours: synthesis and preclinical results
CA2165228A1 (en) Metal chelate forming peptides and use thereof
ES2929507T3 (es) Método para marcar una molécula directora biológica mediante conjugación con un radioisótopo adecuado para formación de imágenes por PET o SPECT
HK1226050A1 (en) Purification method and compositions
JP2016532700A (ja) 放射性標識方法
US20060263295A1 (en) Chelators for radioactively labeled conjugates comprising a stabilizing sidechain
TW202241926A (zh) 用於診斷及治療之改良的膽囊收縮素-2受體(cck2r)標靶
US6342201B1 (en) Complex compounds for diagnosis of vascular diseases
TW202231655A (zh) 用於診斷及治療之改良的膽囊收縮素-2受體(cck2r)標靶
WO2022167471A1 (en) Improved cholecystokinin-2 receptor (cck2r) targeting for diagnosis and therapy
EP2710027A1 (en) Bombesin receptor targeting peptide incorporating a 1, 2, 3-triazole group in the backbone for preparing in vivo diagnostic and therapeutic agents
Hendrikx et al. Research Article Use of Cyclic Backbone NGR-Based SPECT to Increase Efficacy of Postmyocardial Infarction Angiogenesis Imaging