|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
JP2008540436A
(ja)
*
|
2005-05-03 |
2008-11-20 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
Ｊａｋキナーゼインヒビターおよびそれらの使用
|
|
WO2008009458A1
(en)
|
2006-07-21 |
2008-01-24 |
Novartis Ag |
2, 4 -di (arylaminio) -pyrimidine-5-carboxamide compounds as jak kinases inhibitors
|
|
KR20100132550A
(ko)
*
|
2008-04-16 |
2010-12-17 |
포톨라 파마슈티컬스, 인코포레이티드 |
ｓｙｋ 또는 ＪＡＫ 키나제 억제제로서의 ２,６－디아미노-피리미딘－５－일－카르복스아미드
|
|
CA2723205C
(en)
|
2008-04-16 |
2017-03-14 |
Portola Pharmaceuticals, Inc. |
2,6-diamino-pyrimidin-5-yl-carboxamides as syk or jak kinase inhibitors
|
|
TWI548621B
(zh)
|
2011-04-22 |
2016-09-11 |
標誌製藥公司 |
經取代之二胺基甲醯胺及二胺基甲腈嘧啶、其組合物、及以該等治療之方法
|
|
KR20140108594A
(ko)
|
2012-01-10 |
2014-09-11 |
에프. 호프만-라 로슈 아게 |
피리다진 아미드 화합물 및 syk 저해제로서의 이의 용도
|
|
UY34807A
(es)
|
2012-05-16 |
2013-12-31 |
Novartis Ag |
Derivados monocíclicos de heteroarilcicloalquil- diamina
|
|
US9040530B2
(en)
*
|
2012-06-22 |
2015-05-26 |
Portola Pharmaceuticals, Inc. |
1,2,4-triazine-6-carboxamide kinase inhibitors
|
|
HRP20220766T1
(hr)
|
2012-11-08 |
2022-09-16 |
Bristol-Myers Squibb Company |
Amidom-supstituirani heterociklički spojevi korisni kao modulatori il-12, il-23 i/ili ifn alfa odgovora
|
|
EP2922841B8
(en)
|
2012-11-08 |
2017-08-02 |
Bristol-Myers Squibb Company |
Alkyl-amide-substituted pyridyl compounds useful as modulators of il-12, il-23 and/or ifn alpha responses
|
|
JP2014198693A
(ja)
|
2013-03-29 |
2014-10-23 |
大鵬薬品工業株式会社 |
免疫疾患の予防及び／又は治療剤
|
|
AR094537A1
(es)
|
2013-11-07 |
2015-08-12 |
Bristol Myers Squibb Co |
COMPUESTOS DE PIRIDILO SUSTITUIDOS CON ALQUILAMIDA ÚTILES COMO MODULADORES DE LAS RESPUESTAS DE IL-12, IL-23 Y/O IFNa
|
|
GB201717260D0
(en)
|
2017-10-20 |
2017-12-06 |
Galapagos Nv |
Novel compounds and pharma ceutical compositions thereof for the treatment of inflammatory disorders
|
|
MY202167A
(en)
|
2017-11-21 |
2024-04-12 |
Bristol Myers Squibb Co |
Sulfone pyridine alkyl amide-substituted heteroaryl compounds
|
|
JP7485609B2
(ja)
*
|
2018-03-22 |
2024-05-16 |
ブリストル－マイヤーズ スクイブ カンパニー |
ＩＬ－１２、ＩＬ－２３および／またはＩＦＮα応答のモジュレーターとして有用なピリジン含有ヘテロ環式化合物
|
|
RS66346B1
(sr)
*
|
2018-10-22 |
2025-01-31 |
Alumis Inc |
Inhibitori tyk2 i njihova upotreba
|
|
KR102858043B1
(ko)
|
2018-10-30 |
2025-09-10 |
브리스톨-마이어스 스큅 컴퍼니 |
Il-12, il-23 및/또는 ifn-알파의 조정과 관련된 상태의 치료를 위한 아미드-치환된 헤테로시클릭 화합물
|
|
KR102943760B1
(ko)
*
|
2019-01-28 |
2026-03-26 |
장쑤 한서 파마슈티칼 그룹 캄파니 리미티드 |
피리다진 유도체 억제제, 및 그의 제조 방법 및 용도
|
|
CN111484480B
(zh)
*
|
2019-01-29 |
2023-08-11 |
上海翰森生物医药科技有限公司 |
一种多环类衍生物抑制剂、其制备方法和应用
|
|
WO2020200291A1
(en)
*
|
2019-04-02 |
2020-10-08 |
Cullgen (Shanghai) , Inc. |
Compounds and methods of treating cancers
|
|
CN114787154A
(zh)
*
|
2020-01-19 |
2022-07-22 |
苏州科睿思制药有限公司 |
一种Deucravacitinib的晶型及其制备方法和用途
|
|
ES2981764T3
(es)
*
|
2020-03-11 |
2024-10-10 |
Beijing Innocare Pharma Tech Co Ltd |
Compuestos heterocíclicos para inhibir las actividades de TYK2
|
|
WO2021202652A1
(en)
*
|
2020-04-01 |
2021-10-07 |
Eternity Bioscience Inc. |
Tyrosine kinase 2 inhibitors, preparation methods and medicinal uses thereof
|
|
US20230295119A1
(en)
*
|
2020-04-14 |
2023-09-21 |
Gossamer Bio Services, Inc. |
Substituted pyridines for the treatment of inflammatory diseases
|
|
CN113563309B
(zh)
*
|
2020-04-28 |
2024-12-13 |
浙江海正药业股份有限公司 |
吡啶类衍生物及其制备方法和用途
|
|
US20220002267A1
(en)
|
2020-06-24 |
2022-01-06 |
Eternity Bioscience Inc. |
Tyrosine kinase 2 inhibitors, preparation methods and medicinal uses thereof
|
|
CN113968846A
(zh)
|
2020-07-24 |
2022-01-25 |
上海翰森生物医药科技有限公司 |
一种哒嗪类衍生物的盐、晶型及其制备方法和应用
|
|
TWI912419B
(zh)
*
|
2020-12-02 |
2026-01-21 |
大陸商深圳微芯生物科技股份有限公司 |
羥肟酸酯化合物、其製備方法及其應用
|
|
CN115197196B
(zh)
*
|
2021-04-06 |
2024-06-18 |
扬子江药业集团有限公司 |
Tyk2抑制剂及其用途
|
|
CN116888125B
(zh)
*
|
2021-04-07 |
2024-04-12 |
上海齐鲁制药研究中心有限公司 |
Tyk2抑制剂及其用途
|
|
US12509360B2
(en)
|
2021-04-16 |
2025-12-30 |
Sri Lanka Institute Of Information Technology |
Method of making silver-iron titanate nanoparticles and uses thereof
|