JP2025500874A5 - - Google Patents

Info

Publication number
JP2025500874A5
JP2025500874A5 JP2024535713A JP2024535713A JP2025500874A5 JP 2025500874 A5 JP2025500874 A5 JP 2025500874A5 JP 2024535713 A JP2024535713 A JP 2024535713A JP 2024535713 A JP2024535713 A JP 2024535713A JP 2025500874 A5 JP2025500874 A5 JP 2025500874A5
Authority
JP
Japan
Prior art keywords
seq
expression construct
peptide
gastrointestinal peptide
gastrointestinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024535713A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025500874A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2022/000815 external-priority patent/WO2023131811A2/en
Publication of JP2025500874A publication Critical patent/JP2025500874A/ja
Publication of JP2025500874A5 publication Critical patent/JP2025500874A5/ja
Pending legal-status Critical Current

Links

JP2024535713A 2021-12-15 2022-12-15 消化管ペプチドのポリシストロニック発現 Pending JP2025500874A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163361399P 2021-12-15 2021-12-15
US63/361,399 2021-12-15
PCT/IB2022/000815 WO2023131811A2 (en) 2021-12-15 2022-12-15 Polycistronic expression of gut peptides

Publications (2)

Publication Number Publication Date
JP2025500874A JP2025500874A (ja) 2025-01-15
JP2025500874A5 true JP2025500874A5 (enExample) 2025-12-22

Family

ID=86732042

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024535713A Pending JP2025500874A (ja) 2021-12-15 2022-12-15 消化管ペプチドのポリシストロニック発現

Country Status (10)

Country Link
US (1) US20250302992A1 (enExample)
EP (1) EP4448555A2 (enExample)
JP (1) JP2025500874A (enExample)
KR (1) KR20240133712A (enExample)
CN (1) CN118434758A (enExample)
AU (1) AU2022431978B2 (enExample)
CA (1) CA3239128A1 (enExample)
IL (1) IL313462A (enExample)
MX (1) MX2024007519A (enExample)
WO (1) WO2023131811A2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026092369A1 (zh) * 2024-10-31 2026-05-07 派格生物医药(杭州)股份有限公司 一种环状rna分子及其应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ511037A (en) 1998-09-17 2005-02-25 Univ Florida Methods for treatment of degenerative retinal diseases
AU2002327430A1 (en) * 2001-08-08 2003-02-24 Genzyme Corporation Methods for treating diabetes and other blood sugar disorders
ATE514776T1 (de) * 2004-10-05 2011-07-15 California Inst Of Techn Aptamer-regulierte nukleinsäuren und verwendungen davon
US7829664B2 (en) * 2007-06-01 2010-11-09 Boehringer Ingelheim International Gmbh Modified nucleotide sequence encoding glucagon-like peptide-1 (GLP-1), nucleic acid construct comprising same for production of glucagon-like peptide-1 (GLP-1), human cells comprising said construct and insulin-producing constructs, and methods of use thereof
EA037120B1 (ru) 2015-02-02 2021-02-09 МЕИРЭДжТиЭкс ЮКей II ЛИМИТЕД Регулирование экспрессии генов посредством аптамер-опосредованного модулирования альтернативного сплайсинга
MX2018009370A (es) 2016-02-02 2018-11-12 Meiragtx Uk Ii Ltd Regulacion de expresion genica a través de poliadenilacion modulada por aptámeros.
SG11201806589UA (en) 2016-02-02 2018-09-27 Meiragtx Uk Ii Ltd Regulation of gene expression via aptamer-mediated control of self-cleaving ribozymes
US11311633B2 (en) * 2016-04-16 2022-04-26 University Of Florida Research Foundation, Incorporated Satiation peptides for weight loss and altered taste sensitivity
MA44546B1 (fr) 2016-06-15 2021-03-31 Univ California Virus adéno-associés variants et procédés d'utilisation
WO2018156658A1 (en) 2017-02-21 2018-08-30 MEIRAGTX, UK II Limited Regulation of gene expression by aptamer-mediated accessibility of polyadenylation signals
US11739333B2 (en) 2017-03-02 2023-08-29 Meiragtx Uk Ii Limited Regulation of gene expression by aptamer-modulated RNase p cleavage

Similar Documents

Publication Publication Date Title
JP7830441B2 (ja) Glp-1/gip二重アゴニスト
JP2507106B2 (ja) インスリン様成長因子1(igf―1)または因子2(igf―2)の類縁ペプチド
KR20110049797A (ko) 장기 작용성 인터페론 및 그의 유도체 및 그 방법
CN104302772A (zh) 用于糖尿病治疗的蛋白、蛋白缀合物及其应用
JP2010516758A5 (enExample)
CA2627200A1 (en) Novel activin receptor and its uses in treating metabolic disorders
JP2022502077A5 (enExample)
RU2012109553A (ru) Модифицированные вазоактивные интестинальные пептиды
JP2014519852A5 (enExample)
CN111566123A (zh) 胰高血糖素样肽的制备方法
EA011653B1 (ru) Аналоги и гибридные полипептиды gip с избираемыми свойствами
JP2013501038A5 (enExample)
EP0929576A1 (en) Glp-2 derivatives
JP2020519292A5 (enExample)
EA007154B1 (ru) Слитый белок из числа регуляторных/вспомогательных белков вич
AU2008334783A1 (en) Insulinotropic peptide synthesis using solid and solution phase combination techniques
WO2018011803A1 (en) Fusion proteins with extended serum half life
JP2025504625A5 (enExample)
JP2024539139A5 (enExample)
CN113748125A (zh) 胰高血糖素样肽-1(glp-1)受体激动剂及其类似物的制备方法
JP2023548945A5 (enExample)
JP2024069465A5 (enExample)
WO2012048653A1 (zh) 干扰素-白蛋白结合肽的融合蛋白及其用途
MX2011002885A (es) Proceso para la sintesis de (aib8,35)hglp-1(7-36)-nh2.
AU2021304762A1 (en) Novel polypeptide and therapeutic use thereof