JP2025183238A5 - - Google Patents

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Publication number
JP2025183238A5
JP2025183238A5 JP2025139442A JP2025139442A JP2025183238A5 JP 2025183238 A5 JP2025183238 A5 JP 2025183238A5 JP 2025139442 A JP2025139442 A JP 2025139442A JP 2025139442 A JP2025139442 A JP 2025139442A JP 2025183238 A5 JP2025183238 A5 JP 2025183238A5
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JP
Japan
Prior art keywords
compound
subject
substituted
pharmaceutical composition
unsubstituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2025139442A
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English (en)
Japanese (ja)
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JP2025183238A (ja
Filing date
Publication date
Priority claimed from PCT/US2020/061659 external-priority patent/WO2021102361A1/en
Application filed filed Critical
Publication of JP2025183238A publication Critical patent/JP2025183238A/ja
Publication of JP2025183238A5 publication Critical patent/JP2025183238A5/ja
Pending legal-status Critical Current

Links

JP2025139442A 2019-11-22 2025-08-25 カスパーゼ6阻害剤およびその使用 Pending JP2025183238A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962939263P 2019-11-22 2019-11-22
US62/939,263 2019-11-22
PCT/US2020/061659 WO2021102361A1 (en) 2019-11-22 2020-11-20 Caspase 6 inhibitors and uses thereof
JP2022529561A JP7734663B2 (ja) 2019-11-22 2020-11-20 カスパーゼ6阻害剤およびその使用

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022529561A Division JP7734663B2 (ja) 2019-11-22 2020-11-20 カスパーゼ6阻害剤およびその使用

Publications (2)

Publication Number Publication Date
JP2025183238A JP2025183238A (ja) 2025-12-16
JP2025183238A5 true JP2025183238A5 (https=) 2026-03-06

Family

ID=75981720

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022529561A Active JP7734663B2 (ja) 2019-11-22 2020-11-20 カスパーゼ6阻害剤およびその使用
JP2025139442A Pending JP2025183238A (ja) 2019-11-22 2025-08-25 カスパーゼ6阻害剤およびその使用

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2022529561A Active JP7734663B2 (ja) 2019-11-22 2020-11-20 カスパーゼ6阻害剤およびその使用

Country Status (11)

Country Link
US (1) US20250263366A2 (https=)
EP (1) EP4061341A4 (https=)
JP (2) JP7734663B2 (https=)
KR (1) KR20220159346A (https=)
CN (1) CN115335039A (https=)
AU (1) AU2020386639A1 (https=)
BR (1) BR112022009881A2 (https=)
CA (1) CA3162470A1 (https=)
IL (1) IL293222A (https=)
MX (1) MX2022006052A (https=)
WO (1) WO2021102361A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022328634A1 (en) 2021-08-18 2024-02-22 Chemocentryx, Inc. Aryl sulfonyl compounds as ccr6 inhibitors
WO2023023532A2 (en) 2021-08-18 2023-02-23 Chemocentryx, Inc. Aryl sulfonyl (hydroxy) piperidines as ccr6 inhibitors
KR20250030560A (ko) * 2023-08-25 2025-03-05 재단법인 아산사회복지재단 Htra 활성제를 유효성분으로 포함하는 퇴행성 질환의 예방 또는 치료용 약학적 조성물 및 htra 활성 조절제의 스크리닝 방법

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6620839B2 (en) 2000-07-13 2003-09-16 Abbott Laboratories 1,3-disubstituted and 1,3,3-trisubstituted pyrrolidines as histamine-3 receptor ligands and their therapeutic applications
PT2322525E (pt) 2006-04-21 2013-12-26 Novartis Ag Derivados de purina para utilização como agonistas do recetor de adenosina a2a
WO2009089011A2 (en) * 2008-01-08 2009-07-16 Sirtris Pharmaceuticals, Inc. Resveratrol formulations
WO2009148923A1 (en) 2008-05-29 2009-12-10 Bristol-Myers Squibb Company Hepatitis c virus inhibitors
US8889716B2 (en) * 2011-05-10 2014-11-18 Chdi Foundation, Inc. Transglutaminase TG2 inhibitors, pharmaceutical compositions, and methods of use thereof
WO2014060392A1 (en) * 2012-10-16 2014-04-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Caspase-6 inhibitors for treating t cell activation and/or proliferation disorders
CA2904393A1 (en) * 2013-03-15 2014-09-25 Araxes Pharma Llc Covalent inhibitors of kras g12c
EP3092225B1 (en) 2014-01-09 2019-02-27 Merck Patent GmbH Pyrimidine pyrazolyl derivatives and their use as irak inhibitors
WO2016020732A1 (en) * 2014-08-05 2016-02-11 The University Of British Columbia Modulators of caspase-6
CN104860891B (zh) * 2014-02-25 2017-06-30 上海海雁医药科技有限公司 芳氨基嘧啶类化合物及其应用以及由其制备的药物组合物和药用组合物
KR20160002318A (ko) * 2014-06-30 2016-01-07 한미약품 주식회사 피리미딘 유도체 화합물 및 이의 용도
PE20190710A1 (es) 2014-10-24 2019-05-17 Bristol Myers Squibb Co Compuestos de indol carboxamida utiles como inhibidores de cinasas
ES2899196T3 (es) 2015-03-09 2022-03-10 Aurigene Discovery Tech Ltd Derivados de pirazolo[1,5-a][1,3,5]triazina y de pirazolo[1,5-a]pirimidina como inhibidores de CDK
WO2017070256A2 (en) 2015-10-19 2017-04-27 Araxes Pharma Llc Method for screening inhibitors of ras
WO2018022897A1 (en) * 2016-07-27 2018-02-01 Padlock Therapeutics, Inc. Covalent inhibitors of pad4
WO2018035061A1 (en) * 2016-08-15 2018-02-22 Neupharma, Inc. Certain chemical entities, compositions, and methods
AU2017363313B2 (en) 2016-11-22 2021-06-24 Dana-Farber Cancer Institute, Inc. Inhibitors of interleukin-1 receptor-associated kinases and uses thereof
KR20190043437A (ko) 2017-10-18 2019-04-26 씨제이헬스케어 주식회사 단백질 키나제 억제제로서의 헤테로고리 화합물
IL301691A (en) * 2020-09-30 2023-05-01 Univ Leuven Kath 1,2,3,4-tetrahydroquinoline derivatives as inhibitors of the yap/taz-tead activation for treating cancer

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