JP2022529806A5 - - Google Patents

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Publication number
JP2022529806A5
JP2022529806A5 JP2021562811A JP2021562811A JP2022529806A5 JP 2022529806 A5 JP2022529806 A5 JP 2022529806A5 JP 2021562811 A JP2021562811 A JP 2021562811A JP 2021562811 A JP2021562811 A JP 2021562811A JP 2022529806 A5 JP2022529806 A5 JP 2022529806A5
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JP
Japan
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same
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item
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Pending
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JP2021562811A
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English (en)
Japanese (ja)
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JP2022529806A (ja
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Priority claimed from PCT/US2020/029066 external-priority patent/WO2020219417A1/en
Publication of JP2022529806A publication Critical patent/JP2022529806A/ja
Publication of JP2022529806A5 publication Critical patent/JP2022529806A5/ja
Pending legal-status Critical Current

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JP2021562811A 2019-04-24 2020-04-21 E-セレクチン、ガレクチン-3、および/またはcxcr4ケモカイン受容体のガラクトース連結型多量体糖模倣性阻害剤 Pending JP2022529806A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962838206P 2019-04-24 2019-04-24
US62/838,206 2019-04-24
PCT/US2020/029066 WO2020219417A1 (en) 2019-04-24 2020-04-21 Galactose-linked multimeric glycomimetic inhibitors of e-selectins, galectin-3, and/or cxcr4 chemokine receptors

Publications (2)

Publication Number Publication Date
JP2022529806A JP2022529806A (ja) 2022-06-24
JP2022529806A5 true JP2022529806A5 (https=) 2023-04-24

Family

ID=70680623

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021562811A Pending JP2022529806A (ja) 2019-04-24 2020-04-21 E-セレクチン、ガレクチン-3、および/またはcxcr4ケモカイン受容体のガラクトース連結型多量体糖模倣性阻害剤

Country Status (9)

Country Link
US (1) US20230079833A1 (https=)
EP (1) EP3958978A1 (https=)
JP (1) JP2022529806A (https=)
KR (1) KR20220012246A (https=)
CN (1) CN114340736A (https=)
AU (1) AU2020263266A1 (https=)
BR (1) BR112021021244A2 (https=)
CA (1) CA3136661A1 (https=)
WO (1) WO2020219417A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3122321A1 (en) 2018-12-27 2020-07-02 Glycomimetics, Inc. Galectin-3 inhibiting c-glycosides
ES3063748T3 (en) * 2019-07-31 2026-04-20 Crescent Biopharma Inc E-selectin antagonists for use in enhancing the survival of reconstituted, bone marrow-depleted hosts
US20230147312A1 (en) 2020-03-27 2023-05-11 Glycomimetics, Inc. Treatment of acute respiratory distress syndrome and related conditions with antagonists of e-selectin
WO2021247396A1 (en) 2020-05-31 2021-12-09 Magnani John L Compounds and methods for reduction of cancer cell burden and protection of normal hematopoiesis
AU2021292458A1 (en) 2020-06-14 2023-01-19 GlycoMimetics Compositions and methods for overcoming microenvironment-mediated resistance via e-selectin targeting
US20240269157A1 (en) 2021-08-03 2024-08-15 Glycomimetics, Inc. Compositions and methods for overcoming microenvironment-mediated resistance via e-selectin targeting

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003097658A2 (en) 2002-05-16 2003-11-27 Glycomimetics, Inc. Compounds and methods for inhibiting selectin-mediated function
SE0401300D0 (sv) 2004-05-21 2004-05-21 Forskarpatent I Syd Ab Novel Galactoside Inhibitors of Galectins
PL2264043T3 (pl) 2005-09-02 2018-04-30 Glycomimetics, Inc. Heterobifunkcyjne inhibitory pan-selektyny
EP2074132B1 (en) 2006-10-12 2013-05-15 GlycoMimetics, Inc. Glycomimetic replacements for hexoses and n-acetyl hexosamines
ES2543063T3 (es) 2008-05-16 2015-08-14 Galecto Biotech Ab Nueva síntesis de inhibidores de galactósidos
KR102055958B1 (ko) 2011-12-22 2019-12-13 글리코미메틱스, 인크. E-셀렉틴 길항제 화합물, 조성물, 및 이용 방법
CA2888527A1 (en) * 2012-10-31 2014-05-08 Glycomimetics, Inc. E-selectin antagonists compounds and methods of use
JP6689854B2 (ja) 2014-12-03 2020-04-28 グリコミメティクス, インコーポレイテッド E−セレクチンおよびcxcr4ケモカイン受容体のヘテロ二官能性阻害剤
AU2017341065B2 (en) * 2016-10-07 2023-04-06 Crescent Biopharma, Inc. Highly potent multimeric E-selectin antagonists

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