JP2025176137A5 - - Google Patents
Info
- Publication number
- JP2025176137A5 JP2025176137A5 JP2025151940A JP2025151940A JP2025176137A5 JP 2025176137 A5 JP2025176137 A5 JP 2025176137A5 JP 2025151940 A JP2025151940 A JP 2025151940A JP 2025151940 A JP2025151940 A JP 2025151940A JP 2025176137 A5 JP2025176137 A5 JP 2025176137A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- alkyl
- independently
- carbons
- membered ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202063118568P | 2020-11-25 | 2020-11-25 | |
| US63/118,568 | 2020-11-25 | ||
| JP2023531536A JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
| PCT/US2021/060763 WO2022115563A1 (en) | 2020-11-25 | 2021-11-24 | Extended release hydrogel conjugates of c-natriuretic peptides |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023531536A Division JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025176137A JP2025176137A (ja) | 2025-12-03 |
| JP2025176137A5 true JP2025176137A5 (enExample) | 2026-01-05 |
Family
ID=81754916
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023531536A Active JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
| JP2025151940A Pending JP2025176137A (ja) | 2020-11-25 | 2025-09-12 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023531536A Active JP7837333B2 (ja) | 2020-11-25 | 2021-11-24 | Ｃ－ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20240041982A1 (enExample) |
| EP (1) | EP4251150A4 (enExample) |
| JP (2) | JP7837333B2 (enExample) |
| CN (1) | CN116635027A (enExample) |
| WO (1) | WO2022115563A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3236278A1 (en) | 2021-12-13 | 2023-06-22 | Kennett Sprogoe | Effective doses of cnp conjugates |
| WO2023227505A1 (en) | 2022-05-23 | 2023-11-30 | Ascendis Pharma Growth Disorders A/S | Liquid pharmaceutical formulations of cnp compounds |
| WO2024104922A1 (en) | 2022-11-14 | 2024-05-23 | Ascendis Pharma Growth Disorders A/S | Method of improving skeletal muscle function |
| JP2026510974A (ja) | 2023-03-20 | 2026-04-10 | アセンディス ファーマ グロース ディスオーダーズ エー／エス | 軟骨形成不全症のヒト対象における胸腰椎奇形の治療の方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1623994A3 (en) * | 1999-05-17 | 2008-07-16 | ConjuChem Biotechnologies Inc. | Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components |
| WO2010033216A1 (en) * | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Polymer conjugates of nesiritide peptides |
| HUE032582T2 (en) * | 2009-05-20 | 2017-09-28 | Biomarin Pharm Inc | Variants of c-type natriuretic peptide |
| JP6158185B2 (ja) * | 2011-09-07 | 2017-07-05 | プロリンクス エルエルシー | 生分解性架橋を有するヒドロゲル |
| CA2972318A1 (en) * | 2015-01-09 | 2016-07-14 | Ascendis Pharma Growth Disorders A/S | Prodrugs of c-type natriuretic peptide(cnp) |
| EP3386531B1 (en) * | 2015-12-08 | 2021-10-13 | BioMarin Pharmaceutical Inc. | Use of c-type natriuretic peptide variants to treat osteoarthritis |
| NZ743488A (en) * | 2016-01-08 | 2023-02-24 | Ascendis Pharma Growth Disorders As | Controlled-release cnp agonists with low initial npr-b activity |
| AU2017205690B2 (en) * | 2016-01-08 | 2022-04-28 | Ascendis Pharma Growth Disorders A/S | Controlled-release CNP agonists with increased NEP stability |
| AU2017205688C1 (en) * | 2016-01-08 | 2022-03-10 | Ascendis Pharma Growth Disorders A/S | Cnp prodrugs with carrier attachment at the ring moiety |
| JP7017248B2 (ja) * | 2016-03-16 | 2022-02-08 | プロリンクス エルエルシー | エキセナチド類似体の持続放出コンジュゲート |
| EP3484523A1 (en) * | 2016-07-13 | 2019-05-22 | Ascendis Pharma A/S | Conjugation method for carrier-linked prodrugs |
| CN114286693A (zh) * | 2019-04-05 | 2022-04-05 | 普罗林科斯有限责任公司 | 改良偶联接头 |
| SG11202111175YA (en) * | 2019-04-26 | 2021-11-29 | Prolynx Llc | Slow-release cytokine conjugates |
-
2021
- 2021-11-24 JP JP2023531536A patent/JP7837333B2/ja active Active
- 2021-11-24 EP EP21899093.5A patent/EP4251150A4/en active Pending
- 2021-11-24 WO PCT/US2021/060763 patent/WO2022115563A1/en not_active Ceased
- 2021-11-24 US US18/038,687 patent/US20240041982A1/en active Pending
- 2021-11-24 CN CN202180079063.9A patent/CN116635027A/zh active Pending
-
2025
- 2025-09-12 JP JP2025151940A patent/JP2025176137A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPH05117385A (ja) | ブロツク共重合体の製造法、ブロツク共重合体及び水溶性高分子抗癌剤 | |
| JP5856069B2 (ja) | 新規なシチジン系代謝拮抗剤の高分子誘導体 | |
| JP3268913B2 (ja) | 高分子担体 | |
| CN1154512C (zh) | 喜树碱的聚合衍生物 | |
| JP2694923B2 (ja) | 水溶性高分子化医薬製剤 | |
| JP2002525284A5 (enExample) | ||
| EA016911B1 (ru) | Полиглутаминовые кислоты, функционализированные катионными и гидрофобными группами, и их применения, в частности терапевтические применения | |
| JPH06206815A (ja) | ブロック共重合体−抗癌剤複合体医薬製剤 | |
| JP2007501809A5 (enExample) | ||
| JP2020508985A5 (enExample) | ||
| CN103881088B (zh) | 一种响应性聚合物胶束载药体系及其制备方法 | |
| JP2003530317A5 (enExample) | ||
| JPH09501674A (ja) | ミトマイシンを組み込む薬配達薬剤 | |
| JPH06206830A (ja) | ブロック共重合体−薬剤複合体及び高分子ブロック共重合体 | |
| EP3484523A1 (en) | Conjugation method for carrier-linked prodrugs | |
| JP2025514282A5 (enExample) | ||
| CN111529715A (zh) | 一种右旋糖酐-二十二碳六烯酸偶联聚合物及其合成方法和应用 | |
| CN1252130C (zh) | 亲水性聚合物与丹参酮类药物的结合物以及包含该结合物的药物组合物 | |
| CN1246059A (zh) | 聚合物 | |
| CN101265331B (zh) | Peg改性phpma材料及其制备方法 | |
| JP3111099B2 (ja) | 水溶性高分子化薬剤の製造法 | |
| CN102935237B (zh) | 阿霉素键合药及其制备方法 | |
| CN102617852A (zh) | 马来酰亚胺-聚谷氨酸-天冬氨酸聚合物和其复合物、及其制备方法和用途 | |
| CN112424239B (zh) | 高分子化合物及使用了该高分子化合物的细胞内化合物导入促进剂 | |
| CN1611524A (zh) | 聚乙二醇氨基酸n－内环羰酐活性衍生物及其药物键合物和凝胶 |