JP2025118591A5 - - Google Patents
Info
- Publication number
- JP2025118591A5 JP2025118591A5 JP2025044879A JP2025044879A JP2025118591A5 JP 2025118591 A5 JP2025118591 A5 JP 2025118591A5 JP 2025044879 A JP2025044879 A JP 2025044879A JP 2025044879 A JP2025044879 A JP 2025044879A JP 2025118591 A5 JP2025118591 A5 JP 2025118591A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- antibody
- amino acid
- acid sequence
- virus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862765284P | 2018-08-20 | 2018-08-20 | |
| US62/765,284 | 2018-08-20 | ||
| JP2021509865A JP7713880B2 (ja) | 2018-08-20 | 2019-08-20 | アンタゴニスト性抗腫瘍壊死因子受容体スーパーファミリーポリペプチド |
| PCT/US2019/047330 WO2020041361A1 (en) | 2018-08-20 | 2019-08-20 | Antagonistic anti-tumor necrosis factor receptor superfamily polypeptides |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021509865A Division JP7713880B2 (ja) | 2018-08-20 | 2019-08-20 | アンタゴニスト性抗腫瘍壊死因子受容体スーパーファミリーポリペプチド |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025118591A JP2025118591A (ja) | 2025-08-13 |
| JP2025118591A5 true JP2025118591A5 (https=) | 2025-12-25 |
Family
ID=69591189
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021509865A Active JP7713880B2 (ja) | 2018-08-20 | 2019-08-20 | アンタゴニスト性抗腫瘍壊死因子受容体スーパーファミリーポリペプチド |
| JP2025044879A Pending JP2025118591A (ja) | 2018-08-20 | 2025-03-19 | アンタゴニスト性抗腫瘍壊死因子受容体スーパーファミリーポリペプチド |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021509865A Active JP7713880B2 (ja) | 2018-08-20 | 2019-08-20 | アンタゴニスト性抗腫瘍壊死因子受容体スーパーファミリーポリペプチド |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20210340268A1 (https=) |
| EP (1) | EP3840782A4 (https=) |
| JP (2) | JP7713880B2 (https=) |
| KR (2) | KR20210061350A (https=) |
| CN (1) | CN112955179A (https=) |
| CA (1) | CA3109954A1 (https=) |
| WO (1) | WO2020041361A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3936137A1 (en) * | 2013-02-07 | 2022-01-12 | The General Hospital Corporation | Methods for expansion or depletion of t-regulatory cells |
| CN115043943A (zh) | 2015-05-15 | 2022-09-13 | 综合医院公司 | 拮抗性抗肿瘤坏死因子受体超家族抗体 |
| KR102669985B1 (ko) | 2015-06-30 | 2024-05-29 | 샌포드 번햄 프레비즈 메디컬 디스커버리 인스티튜트 | Btla 융합 단백질 작용제 및 이의 용도 |
| US20190135929A1 (en) | 2015-08-28 | 2019-05-09 | The General Hospital Corporation | Agonistic anti-tumor necrosis factor receptor 2 antibodies |
| US11859002B2 (en) | 2016-05-13 | 2024-01-02 | The General Hospital Corporation | Antagonistic anti-tumor necrosis factor receptor 2 antibodies |
| CN112955179A (zh) * | 2018-08-20 | 2021-06-11 | 综合医院公司 | 拮抗性抗肿瘤坏死因子受体超家族多肽 |
| CN113302205B (zh) | 2018-11-15 | 2024-12-06 | 综合医院公司 | 激动性肿瘤坏死因子受体超家族多肽 |
| EP4149627A4 (en) * | 2020-05-14 | 2024-05-29 | The General Hospital Corporation | POLYPEPTIDE AGONISTS OF THE TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY |
| TWI878554B (zh) | 2020-06-12 | 2025-04-01 | 大陸商南京維立志博生物科技股份有限公司 | 結合ｔｎｆｒ２的抗體及其用途 |
| CN112159818B (zh) * | 2020-08-20 | 2023-02-21 | 山东兴瑞生物科技有限公司 | 用于治疗hcc的核酸、其制备方法、具有该核酸的car-t细胞及细胞的制备方法 |
| US20240101693A1 (en) * | 2021-01-21 | 2024-03-28 | The General Hospital Corporation | Antagonistic anti-tumor necrosis factor receptor superfamily antibodies |
| CN117858893A (zh) * | 2021-06-30 | 2024-04-09 | 盛禾(中国)生物制药有限公司 | 一种抗tnfr2单域抗体及其制备方法和应用 |
| CN116334768A (zh) * | 2022-07-14 | 2023-06-27 | 上海肽盛医药有限公司 | 一种结构多样的多肽库及其构建方法和应用 |
| WO2024219994A1 (ru) * | 2023-04-16 | 2024-10-24 | федеральное государственное бюджетное учреждение "Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи" Министерства здравоохранения Российской Федерации | Экспрессионный вектор на основе аденовируса человека 19 серотипа и способ его применения |
| CN116650660B (zh) * | 2023-07-27 | 2023-11-03 | 上海偌妥生物科技有限公司 | 制备抗体偶联小分子药物的方法及其应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5677425A (en) * | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| CN1771055A (zh) * | 2002-09-05 | 2006-05-10 | 免疫医疗公司 | 通过施用cd2拮抗剂预防或治疗t细胞恶性肿瘤的方法 |
| US7592429B2 (en) * | 2005-05-03 | 2009-09-22 | Ucb Sa | Sclerostin-binding antibody |
| JP5898082B2 (ja) * | 2009-10-07 | 2016-04-06 | マクロジェニクス，インコーポレーテッド | フコシル化程度の変更により改良されたエフェクター機能を示すＦｃ領域含有ポリペプチドおよびその使用法 |
| AU2015237864B2 (en) * | 2014-03-24 | 2020-12-03 | Cancer Research Technology Limited | Modified antibodies containing modified IgG2 domains which elicit agonist or antagonistic properties and use thereof |
| WO2016094309A1 (en) * | 2014-12-10 | 2016-06-16 | Myosotis | Inhibition of tnf signaling in cancer immunotherapy |
| CA3004830A1 (en) * | 2015-11-11 | 2017-05-18 | Opi Vi- Ip Holdco Llc | Composition and methods for anti-tnfr2 antibodies |
| US11859002B2 (en) * | 2016-05-13 | 2024-01-02 | The General Hospital Corporation | Antagonistic anti-tumor necrosis factor receptor 2 antibodies |
| BR112019001206A2 (pt) * | 2016-07-20 | 2019-06-25 | Aerpio Therapeutics Inc | anticorpos monoclonais humanizados que visam ve-ptp (hptp-ss) |
| WO2018031400A1 (en) * | 2016-08-12 | 2018-02-15 | Janssen Biotech, Inc. | Fc engineered anti-tnfr superfamily member antibodies having enhanced agonistic activity and methods of using them |
| SG10201912565QA (en) * | 2016-09-29 | 2020-02-27 | Amgen Inc | Low-viscosity antigen binding proteins and methods of making them |
| WO2018092907A1 (ja) * | 2016-11-21 | 2018-05-24 | 国立研究開発法人医薬基盤・健康・栄養研究所 | エピトープ均質化抗体パネル、ならびにその作製方法および利用 |
| US20200347143A1 (en) * | 2016-12-19 | 2020-11-05 | Glenmark Pharmaceuticals S.A. | Novel tnfr agonists and uses thereof |
| CN112955179A (zh) * | 2018-08-20 | 2021-06-11 | 综合医院公司 | 拮抗性抗肿瘤坏死因子受体超家族多肽 |
-
2019
- 2019-08-20 CN CN201980068984.8A patent/CN112955179A/zh active Pending
- 2019-08-20 WO PCT/US2019/047330 patent/WO2020041361A1/en not_active Ceased
- 2019-08-20 JP JP2021509865A patent/JP7713880B2/ja active Active
- 2019-08-20 KR KR1020217008246A patent/KR20210061350A/ko not_active Ceased
- 2019-08-20 KR KR1020257040897A patent/KR20260004528A/ko active Pending
- 2019-08-20 CA CA3109954A patent/CA3109954A1/en active Pending
- 2019-08-20 EP EP19852179.1A patent/EP3840782A4/en active Pending
- 2019-08-20 US US17/269,315 patent/US20210340268A1/en active Pending
-
2023
- 2023-01-09 US US18/152,078 patent/US20230295326A1/en not_active Abandoned
-
2025
- 2025-03-19 JP JP2025044879A patent/JP2025118591A/ja active Pending
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