JP2024515266A5 - - Google Patents

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Publication number
JP2024515266A5
JP2024515266A5 JP2023561850A JP2023561850A JP2024515266A5 JP 2024515266 A5 JP2024515266 A5 JP 2024515266A5 JP 2023561850 A JP2023561850 A JP 2023561850A JP 2023561850 A JP2023561850 A JP 2023561850A JP 2024515266 A5 JP2024515266 A5 JP 2024515266A5
Authority
JP
Japan
Prior art keywords
cancer
antibody
antigen
seq
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023561850A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024515266A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2022/059059 external-priority patent/WO2022214517A1/en
Publication of JP2024515266A publication Critical patent/JP2024515266A/ja
Publication of JP2024515266A5 publication Critical patent/JP2024515266A5/ja
Pending legal-status Critical Current

Links

JP2023561850A 2021-04-08 2022-04-06 抗c-MET抗体及び抗体薬物複合体 Pending JP2024515266A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP21167423 2021-04-08
EP21167423.9 2021-04-08
PCT/EP2022/059059 WO2022214517A1 (en) 2021-04-08 2022-04-06 Anti-c-met antibodies and antibody-drug conjugates

Publications (2)

Publication Number Publication Date
JP2024515266A JP2024515266A (ja) 2024-04-08
JP2024515266A5 true JP2024515266A5 (https=) 2025-03-12

Family

ID=75438640

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023561850A Pending JP2024515266A (ja) 2021-04-08 2022-04-06 抗c-MET抗体及び抗体薬物複合体

Country Status (12)

Country Link
US (1) US20240376214A1 (https=)
EP (1) EP4320152A1 (https=)
JP (1) JP2024515266A (https=)
KR (1) KR20230166099A (https=)
CN (1) CN117157325A (https=)
AU (1) AU2022254291A1 (https=)
BR (1) BR112023020801A2 (https=)
CA (1) CA3214718A1 (https=)
CL (1) CL2023002992A1 (https=)
IL (1) IL306142A (https=)
MX (1) MX2023011929A (https=)
WO (1) WO2022214517A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024108193A2 (en) * 2022-11-18 2024-05-23 Epibiologics, Inc. Degradation of cmet using a bispecific binding agent
WO2024131835A1 (en) * 2022-12-20 2024-06-27 Hansoh Bio Llc Ligand-cytotoxicity drug conjugates and pharmaceutical uses thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2575402A1 (en) 2004-08-05 2006-02-09 Genentech, Inc. Humanized anti-cmet antagonists
PA8849001A1 (es) 2008-11-21 2010-06-28 Lilly Co Eli Anticuerpos de c-met
AR074439A1 (es) * 2008-12-02 2011-01-19 Pf Medicament Anticuerpo anti-cmet (receptor c-met)
PT3056203T (pt) 2010-04-21 2018-02-15 Syntarga Bv Conjugados de análogos de cc-1065 e ligantes bifuncionais
RU2608644C2 (ru) 2010-11-03 2017-01-23 арДЖЕН-ИКС Н.В. Антитела против белка рецептора с-мет
US20140154251A1 (en) 2011-10-05 2014-06-05 Samsung Electronics Co., Ltd. Anti c-met antibody and uses thereof
KR101463098B1 (ko) * 2011-11-28 2014-11-27 한국생명공학연구원 c-Met에 대한 인간항체에 약물이 접합된 약물 복합체 및 이의 용도
KR102150616B1 (ko) * 2013-09-12 2020-09-03 삼성전자주식회사 c-Met 표적 화합물-생체활성 물질 접합체 및 그 용도
SG11201609372UA (en) 2014-05-22 2016-12-29 Synthon Biopharmaceuticals Bv Site-specific conjugation of linker drugs to antibodies and resulting adcs
ES2748295T3 (es) 2014-09-16 2020-03-16 Symphogen As Anticuerpos anti-MET y composiciones
WO2016165580A1 (zh) * 2015-04-17 2016-10-20 江苏恒瑞医药股份有限公司 抗c-Met抗体和抗c-Met抗体-细胞毒性药物偶联物及其医药用途
PL3319597T3 (pl) * 2015-07-10 2021-10-11 Byondis B.V. Kompozycje zawierające koniugaty przeciwciało-duokarmycyna
CA3026139C (en) 2016-02-12 2023-09-12 Synthon Biopharmaceuticals B.V. Selective reduction of cysteine-engineered antibodies
SI3626273T1 (sl) 2016-05-17 2021-04-30 Abbvie Biotherapeutics Inc. Konjugati protitelesa proti CMET in zdravila ter postopki za njihovo uporabo
GB201611123D0 (en) 2016-06-27 2016-08-10 Euremab Srl Anti met antibodiesand uses thereof
HUE054571T2 (hu) * 2016-09-14 2021-09-28 Merck Patent Gmbh Hatékony tumorgátlásra szolgáló C-MET elleni ellenanyagok és ellenanyag-drog konjugátumaik
US11419944B2 (en) 2016-10-11 2022-08-23 Byondis B.V. Non-linear self-immolative linkers and conjugates thereof
TWI782930B (zh) * 2016-11-16 2022-11-11 美商再生元醫藥公司 抗met抗體,結合met之雙特異性抗原結合分子及其使用方法
HRP20210922T1 (hr) * 2016-11-23 2021-09-03 Eli Lilly And Company Konjugati protutijela protiv met s lijekom
US20180230218A1 (en) * 2017-01-04 2018-08-16 Immunogen, Inc. Met antibodies and immunoconjugates and uses thereof
US11696958B2 (en) 2017-05-23 2023-07-11 Byondis B.V. Dual conjugation process for preparing antibody-drug conjugates
JP7325339B2 (ja) * 2017-05-30 2023-08-14 チョン クン ダン ファーマシューティカル コーポレーション 新規な抗c-Met抗体およびその用途
EP3774923A4 (en) * 2018-03-28 2021-12-29 Mitsubishi Tanabe Pharma Corporation Drug conjugates of cmet monoclonal binding agents, and uses thereof

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