JP2024515536A5 - - Google Patents
Info
- Publication number
- JP2024515536A5 JP2024515536A5 JP2023561116A JP2023561116A JP2024515536A5 JP 2024515536 A5 JP2024515536 A5 JP 2024515536A5 JP 2023561116 A JP2023561116 A JP 2023561116A JP 2023561116 A JP2023561116 A JP 2023561116A JP 2024515536 A5 JP2024515536 A5 JP 2024515536A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- cancer
- amino acid
- cdr
- drug conjugate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP21166441.2 | 2021-03-31 | ||
| EP21166441 | 2021-03-31 | ||
| EP21170941.5 | 2021-04-28 | ||
| EP21170941.5A EP4066899A1 (en) | 2021-03-31 | 2021-04-28 | Anti-nectin-4 antibody |
| EP21172723.5 | 2021-05-07 | ||
| EP21172723.5A EP4086284A1 (en) | 2021-05-07 | 2021-05-07 | Anti-nectin-4 antibody exatecan conjugates |
| EP21209332 | 2021-11-19 | ||
| EP21209332.2 | 2021-11-19 | ||
| PCT/EP2022/058629 WO2022207825A1 (en) | 2021-03-31 | 2022-03-31 | Anti-nectin-4 antibody exatecan conjugates |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2024515536A JP2024515536A (ja) | 2024-04-10 |
| JP2024515536A5 true JP2024515536A5 (https=) | 2024-08-13 |
| JP7579991B2 JP7579991B2 (ja) | 2024-11-08 |
Family
ID=80999114
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023561116A Active JP7579991B2 (ja) | 2021-03-31 | 2022-03-31 | 抗ネクチン－４抗体エキサテカンコンジュゲート |
| JP2023561035A Active JP7579990B2 (ja) | 2021-03-31 | 2022-03-31 | 抗ネクチン－４抗体およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023561035A Active JP7579990B2 (ja) | 2021-03-31 | 2022-03-31 | 抗ネクチン－４抗体およびその使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (4) | US20240181075A1 (https=) |
| EP (2) | EP4314057A1 (https=) |
| JP (2) | JP7579991B2 (https=) |
| KR (2) | KR20240035378A (https=) |
| AU (2) | AU2022248735A1 (https=) |
| BR (1) | BR112023017728A2 (https=) |
| CA (2) | CA3212651A1 (https=) |
| CL (2) | CL2023002909A1 (https=) |
| CO (2) | CO2023012821A2 (https=) |
| CR (2) | CR20230470A (https=) |
| DO (2) | DOP2023000213A (https=) |
| EC (2) | ECSP23073625A (https=) |
| IL (2) | IL305951A (https=) |
| JO (2) | JOP20230239A1 (https=) |
| MX (2) | MX2023011563A (https=) |
| PE (2) | PE20240724A1 (https=) |
| SA (1) | SA523450918B1 (https=) |
| WO (3) | WO2022207828A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4285935A1 (en) * | 2022-06-03 | 2023-12-06 | Emergence Therapeutics AG | Novel anti-nectin-4 antibody camptothecin derivative conjugates |
| EP4309676A1 (en) * | 2022-07-22 | 2024-01-24 | Emergence Therapeutics AG | Novel anti-nectin-4 antibody camptothecin derivative conjugates |
| EP4344707A1 (en) * | 2022-09-29 | 2024-04-03 | Emergence Therapeutics AG | New anti-nectin-4 antibody drug conjugates |
| EP4461317A1 (en) * | 2023-05-12 | 2024-11-13 | Emergence Therapeutics GmbH | Antibody-drug conjugates comprising an anti-nectin-4 antibody and belotecan or a derivative thereof |
| WO2024251260A1 (zh) * | 2023-06-08 | 2024-12-12 | 江苏迈威康新药研发有限公司 | 结合Nectin-4的抗体及其用途 |
| JP7689606B2 (ja) * | 2023-06-20 | 2025-06-06 | イーライ リリー アンド カンパニー | ネクチン－４抗体及び抗体－薬物コンジュゲート |
| EP4534101A1 (en) | 2023-10-02 | 2025-04-09 | Eli Lilly and Company | Antibody drug conjugate (adc) targeting nectin 4 and comprising an exatecan payload |
| EP4534102A1 (en) | 2023-10-02 | 2025-04-09 | Eli Lilly and Company | Antibody drug conjugate (adc) targeting nectin 4 and comprising an exatecan payload |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX347954B (es) | 2010-09-29 | 2017-05-19 | Agensys Inc | Conjugados de anticuerpo farmaco (adc) que enlazan a proteinas 191p4d12. |
| EP3347048B1 (en) * | 2015-09-09 | 2020-04-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antibodies having specificity to nectin-4 and uses thereof |
| CA3044898C (en) * | 2016-11-25 | 2022-04-05 | Mabwell (shanghai) Bioscience Co., Ltd. | Di-substituted maleic amide linker for antibody-drug conjugating and preparation method and use thereof |
| CN110392697A (zh) | 2017-03-02 | 2019-10-29 | 国家医疗保健研究所 | 对nectin-4具有特异性的抗体及其用途 |
| JP7381478B2 (ja) * | 2017-10-23 | 2023-11-15 | マブリンク ビオシオンス | 単一分子量ポリサルコシンを含むリガンド－薬物－複合体 |
| NZ781538A (en) * | 2019-04-24 | 2025-12-19 | Heidelberg Pharma Res Gmbh | Amatoxin antibody-drug conjugates and uses thereof |
| US12398206B2 (en) * | 2019-10-07 | 2025-08-26 | Université D'aixmarseille | Antibodies having specificity for nectin-4 and uses thereof |
| WO2021143741A1 (zh) * | 2020-01-15 | 2021-07-22 | 北京海步医药科技有限公司 | 靶向多肽-药物缀合物及其用途 |
| EP4096717B1 (en) * | 2020-01-31 | 2024-12-11 | Innate Pharma | Treatment of cancer |
-
2022
- 2022-03-31 KR KR1020237037560A patent/KR20240035378A/ko active Pending
- 2022-03-31 IL IL305951A patent/IL305951A/en unknown
- 2022-03-31 CA CA3212651A patent/CA3212651A1/en active Pending
- 2022-03-31 EP EP22713963.1A patent/EP4314057A1/en active Pending
- 2022-03-31 IL IL305954A patent/IL305954A/en unknown
- 2022-03-31 MX MX2023011563A patent/MX2023011563A/es unknown
- 2022-03-31 JP JP2023561116A patent/JP7579991B2/ja active Active
- 2022-03-31 CA CA3212655A patent/CA3212655A1/en active Pending
- 2022-03-31 BR BR112023017728A patent/BR112023017728A2/pt unknown
- 2022-03-31 WO PCT/EP2022/058632 patent/WO2022207828A1/en not_active Ceased
- 2022-03-31 JP JP2023561035A patent/JP7579990B2/ja active Active
- 2022-03-31 WO PCT/EP2022/058629 patent/WO2022207825A1/en not_active Ceased
- 2022-03-31 AU AU2022248735A patent/AU2022248735A1/en active Pending
- 2022-03-31 MX MX2023011561A patent/MX2023011561A/es unknown
- 2022-03-31 CR CR20230470A patent/CR20230470A/es unknown
- 2022-03-31 WO PCT/EP2022/058626 patent/WO2022207822A1/en not_active Ceased
- 2022-03-31 CR CR20230469A patent/CR20230469A/es unknown
- 2022-03-31 PE PE2023002763A patent/PE20240724A1/es unknown
- 2022-03-31 AU AU2022250867A patent/AU2022250867A1/en active Pending
- 2022-03-31 EP EP22713962.3A patent/EP4262988A1/en active Pending
- 2022-03-31 US US18/552,056 patent/US20240181075A1/en active Pending
- 2022-03-31 US US18/263,430 patent/US12049500B2/en active Active
- 2022-03-31 PE PE2023002771A patent/PE20240725A1/es unknown
- 2022-03-31 US US18/551,282 patent/US20240173424A1/en active Pending
- 2022-03-31 KR KR1020237037576A patent/KR20240028330A/ko active Pending
-
2023
- 2023-09-27 CO CONC2023/0012821A patent/CO2023012821A2/es unknown
- 2023-09-28 CO CONC2023/0012828A patent/CO2023012828A2/es unknown
- 2023-09-28 JO JOJO/P/2023/0239A patent/JOP20230239A1/ar unknown
- 2023-09-28 CL CL2023002909A patent/CL2023002909A1/es unknown
- 2023-09-28 JO JOJO/P/2023/0238A patent/JOP20230238A1/ar unknown
- 2023-09-28 CL CL2023002907A patent/CL2023002907A1/es unknown
- 2023-09-28 EC ECSENADI202373625A patent/ECSP23073625A/es unknown
- 2023-09-29 DO DO2023000213A patent/DOP2023000213A/es unknown
- 2023-09-29 DO DO2023000214A patent/DOP2023000214A/es unknown
- 2023-09-29 EC ECSENADI202373436A patent/ECSP23073436A/es unknown
- 2023-10-01 SA SA523450918A patent/SA523450918B1/ar unknown
-
2024
- 2024-06-17 US US18/745,729 patent/US20250018053A1/en active Pending
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