JP2024540062A5 - - Google Patents

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Publication number
JP2024540062A5
JP2024540062A5 JP2024525253A JP2024525253A JP2024540062A5 JP 2024540062 A5 JP2024540062 A5 JP 2024540062A5 JP 2024525253 A JP2024525253 A JP 2024525253A JP 2024525253 A JP2024525253 A JP 2024525253A JP 2024540062 A5 JP2024540062 A5 JP 2024540062A5
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JP
Japan
Prior art keywords
amino acid
acid sequence
seq
heavy chain
light chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024525253A
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English (en)
Japanese (ja)
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JP2024540062A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/CN2022/129834 external-priority patent/WO2023078386A1/zh
Publication of JP2024540062A publication Critical patent/JP2024540062A/ja
Publication of JP2024540062A5 publication Critical patent/JP2024540062A5/ja
Pending legal-status Critical Current

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JP2024525253A 2021-11-05 2022-11-04 抗cldn18.2抗体及びその用途 Pending JP2024540062A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN202111307619.3 2021-11-05
CN202111307619 2021-11-05
PCT/CN2022/129834 WO2023078386A1 (zh) 2021-11-05 2022-11-04 抗cldn18.2抗体及其用途

Publications (2)

Publication Number Publication Date
JP2024540062A JP2024540062A (ja) 2024-10-31
JP2024540062A5 true JP2024540062A5 (https=) 2026-01-28

Family

ID=86240666

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024525253A Pending JP2024540062A (ja) 2021-11-05 2022-11-04 抗cldn18.2抗体及びその用途

Country Status (7)

Country Link
US (1) US20240409629A1 (https=)
EP (1) EP4428154A4 (https=)
JP (1) JP2024540062A (https=)
KR (1) KR20240099289A (https=)
CN (1) CN118139888A (https=)
TW (1) TW202323285A (https=)
WO (1) WO2023078386A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024114667A1 (zh) * 2022-11-30 2024-06-06 正大天晴药业集团股份有限公司 抗cldn18.2抗体药物偶联物及其药物组合物和用途

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD120303A1 (https=) 1975-05-15 1976-06-05
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5225539A (en) 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
EP0983303B1 (en) 1997-05-21 2006-03-08 Biovation Limited Method for the production of non-immunogenic proteins
WO2013174403A1 (en) * 2012-05-23 2013-11-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2013174404A1 (en) * 2012-05-23 2013-11-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
WO2016165762A1 (en) * 2015-04-15 2016-10-20 Ganymed Pharmaceuticals Ag Drug conjugates comprising antibodies against claudin 18.2
ES2979068T3 (es) * 2016-07-08 2024-09-24 Crage Medical Co Ltd Anticuerpos para anti-claudina 18A2 y utilización de los mismos
JP2021523090A (ja) * 2018-03-09 2021-09-02 科済生物医薬(上海)有限公司Carsgen Therapeutics Co.,Ltd. 腫瘍を治療するための方法および組成物
WO2019242505A1 (zh) * 2018-06-17 2019-12-26 上海健信生物医药科技有限公司 靶向cldn18.2的抗体、双特异性抗体、adc和car及其应用
KR20210050547A (ko) * 2018-08-27 2021-05-07 난징 산홈 팔마세우티칼 컴퍼니 리미티드 항-클라우딘18.2 항체 및 이의 용도
JP2022511394A (ja) * 2018-09-30 2022-01-31 カファ セラピューティクス リミテッド Cldn18の抗体及び化学療法薬の併用療法
EP3872093A4 (en) * 2018-10-22 2022-10-19 Shanghai Genbase Biotechnology Co., Ltd. ANTI-CLDN18.2 ANTIBODIES AND USES THEREOF
BR112021011014A2 (pt) * 2018-12-07 2021-08-31 Zlip Holding Limited Anticorpos anti-claudina e usos destes
EP3902824A4 (en) * 2018-12-28 2023-01-04 Sparx Therapeutics Inc. FOR CLAUDIN 18.2 SPECIFIC BINDING MOLECULES, COMPOSITIONS AND METHODS OF TREATMENT OF CANCER AND OTHER DISEASES
CN109762067B (zh) * 2019-01-17 2020-02-28 北京天广实生物技术股份有限公司 结合人Claudin 18.2的抗体及其用途
EP3960766A4 (en) 2019-04-19 2022-12-07 Keymed Biosciences Co.,Ltd. ANTI-TUMOR THERAPEUTIC AGENT AND USE THEREOF
CN114206935B (zh) * 2019-05-24 2024-01-12 三优生物医药(上海)有限公司 新型cldn18.2结合分子
KR102777693B1 (ko) * 2019-07-17 2025-03-07 더 리전트 오브 더 유니버시티 오브 캘리포니아 Claudin18 항체 및 암 치료 방법
JP7767270B2 (ja) * 2019-08-20 2025-11-11 スーチョウ トランセンタ セラピューティクス カンパニー,リミテッド 新規抗cldn18.2抗体
CN112480248B (zh) * 2020-11-24 2023-05-05 三优生物医药(上海)有限公司 与cld18a2特异性结合的分子
CN113416260B (zh) * 2021-04-14 2022-02-01 南京凯地医疗技术有限公司 靶向Claudin18.2的特异性嵌合抗原受体细胞及其制备方法和应用

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