JP2024016024A5 - - Google Patents

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Publication number
JP2024016024A5
JP2024016024A5 JP2023172391A JP2023172391A JP2024016024A5 JP 2024016024 A5 JP2024016024 A5 JP 2024016024A5 JP 2023172391 A JP2023172391 A JP 2023172391A JP 2023172391 A JP2023172391 A JP 2023172391A JP 2024016024 A5 JP2024016024 A5 JP 2024016024A5
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JP
Japan
Prior art keywords
chain variable
variable region
light chain
seq
amino acid
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JP2023172391A
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English (en)
Japanese (ja)
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JP7827951B2 (ja
JP2024016024A (ja
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Priority claimed from PCT/CN2021/083194 external-priority patent/WO2021190622A1/en
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Publication of JP2024016024A5 publication Critical patent/JP2024016024A5/ja
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JP2023172391A 2020-03-27 2023-10-03 抗体結合Siglec15及びその使用 Active JP7827951B2 (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202063000566P 2020-03-27 2020-03-27
US63/000,566 2020-03-27
PCT/CN2021/083194 WO2021190622A1 (en) 2020-03-27 2021-03-26 Antibodies binding siglec15 and uses thereof
JP2022547787A JP7364315B2 (ja) 2020-03-27 2021-03-26 抗体結合Siglec15及びその使用

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2022547787A Division JP7364315B2 (ja) 2020-03-27 2021-03-26 抗体結合Siglec15及びその使用

Publications (3)

Publication Number Publication Date
JP2024016024A JP2024016024A (ja) 2024-02-06
JP2024016024A5 true JP2024016024A5 (https=) 2024-04-04
JP7827951B2 JP7827951B2 (ja) 2026-03-11

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ID=77891322

Family Applications (2)

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JP2022547787A Active JP7364315B2 (ja) 2020-03-27 2021-03-26 抗体結合Siglec15及びその使用
JP2023172391A Active JP7827951B2 (ja) 2020-03-27 2023-10-03 抗体結合Siglec15及びその使用

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JP2022547787A Active JP7364315B2 (ja) 2020-03-27 2021-03-26 抗体結合Siglec15及びその使用

Country Status (12)

Country Link
US (2) US11739147B2 (https=)
EP (1) EP4126938A4 (https=)
JP (2) JP7364315B2 (https=)
KR (1) KR102651263B1 (https=)
CN (1) CN115348970B (https=)
AU (2) AU2021240769B2 (https=)
BR (1) BR112022019129A2 (https=)
IL (1) IL296736B2 (https=)
MX (1) MX2022011951A (https=)
PH (1) PH12022552520A1 (https=)
SA (1) SA522440646B1 (https=)
WO (1) WO2021190622A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12022552520A1 (en) * 2020-03-27 2023-01-04 Biosion Inc Antibodies binding siglec15 and uses thereof
TW202330617A (zh) * 2021-11-25 2023-08-01 大陸商正大天晴藥業集團股份有限公司 抗Siglec-15抗體及其應用
CN114134183B (zh) * 2021-12-24 2022-12-06 广东南模生物科技有限公司 一种siglec15基因人源化动物模型的构建方法及应用
CN114807052A (zh) * 2022-06-07 2022-07-29 江苏亲科生物研究中心有限公司 Siglec15单克隆抗体及其制备方法和用途
KR20250023399A (ko) * 2022-06-13 2025-02-18 바이오사이토젠 파마슈티컬스 (베이징) 컴퍼니 리미티드 항-siglec15 항체 및 이의 용도
WO2024040194A1 (en) 2022-08-17 2024-02-22 Capstan Therapeutics, Inc. Conditioning for in vivo immune cell engineering
WO2025247334A1 (en) * 2024-05-30 2025-12-04 Biosion Inc. Recombinant fusion protein targeting siglec15 and gm-csfr

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4604184B2 (ja) * 2005-07-12 2010-12-22 独立行政法人産業技術総合研究所 新規糖鎖認識蛋白質及びその遺伝子
US8168181B2 (en) 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
MX2013003828A (es) * 2010-10-05 2013-06-28 Daiichi Sankyo Co Ltd Anticuerpo dirigido a la proteina lectina tipo inmunoglobulina de union a acido sialico-15 relacionada con osteoclastos.
CA2848074A1 (en) 2011-09-09 2013-03-14 Medimmune Limited Anti-siglec-15 antibodies and uses thereof
BR112014024267A8 (pt) * 2012-03-30 2017-07-25 Daiichi Sankyo Co Ltd anticorpo ou um fragmento de ligação de antígeno do anticorpo, composição farmacêutica, usos de pelo menos um dos anticorpos ou fragmentos de ligação de antígeno e de uma composição, polinucleotídeo, vetor, e, célula hospedeira transformada
HK1210192A1 (en) * 2012-07-19 2016-04-15 Alethia Biotherapeutics Inc. Anti-siglec-15 antibodies
EP3157562A4 (en) * 2014-06-18 2017-12-20 Daiichi Sankyo Company, Limited Anti-siglec-15 antibodies for use in treatment of osteogenesis imperfecta
AU2016354100B2 (en) 2015-11-10 2023-11-30 Yale University Compositions and methods for treating autoimmune diseases and cancers
DK3515478T3 (da) * 2016-09-21 2024-05-21 Nextcure Inc Antistoffer til SIGLEC-15 og fremgangsmåder til anvendelse deraf
CN108250296B (zh) * 2018-01-17 2020-07-07 长春金赛药业有限责任公司 全人源抗人pd-l1单克隆抗体及其应用
JP7156653B2 (ja) * 2018-08-30 2022-10-19 イノベイティブ セルラー セラピューティクス ホールディングス,エルティディ 固形腫瘍を治療するためのキメラ抗原受容体細胞
PH12022552520A1 (en) * 2020-03-27 2023-01-04 Biosion Inc Antibodies binding siglec15 and uses thereof

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