JP2025041725A5 - - Google Patents

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Publication number
JP2025041725A5
JP2025041725A5 JP2024221344A JP2024221344A JP2025041725A5 JP 2025041725 A5 JP2025041725 A5 JP 2025041725A5 JP 2024221344 A JP2024221344 A JP 2024221344A JP 2024221344 A JP2024221344 A JP 2024221344A JP 2025041725 A5 JP2025041725 A5 JP 2025041725A5
Authority
JP
Japan
Prior art keywords
antibody
amino acid
pharmaceutical composition
seq
set forth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024221344A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025041725A (ja
Filing date
Publication date
Priority claimed from PCT/JP2019/048171 external-priority patent/WO2020122034A1/ja
Application filed filed Critical
Publication of JP2025041725A publication Critical patent/JP2025041725A/ja
Publication of JP2025041725A5 publication Critical patent/JP2025041725A5/ja
Pending legal-status Critical Current

Links

JP2024221344A 2018-12-11 2024-12-18 抗体-薬物コンジュゲートとparp阻害剤の組み合わせ Pending JP2025041725A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2018231948 2018-12-11
JP2018231948 2018-12-11
PCT/JP2019/048171 WO2020122034A1 (ja) 2018-12-11 2019-12-10 抗体-薬物コンジュゲートとparp阻害剤の組み合わせ
JP2020560106A JP7608164B2 (ja) 2018-12-11 2019-12-10 抗体-薬物コンジュゲートとparp阻害剤の組み合わせ

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2020560106A Division JP7608164B2 (ja) 2018-12-11 2019-12-10 抗体-薬物コンジュゲートとparp阻害剤の組み合わせ

Publications (2)

Publication Number Publication Date
JP2025041725A JP2025041725A (ja) 2025-03-26
JP2025041725A5 true JP2025041725A5 (enExample) 2025-10-08

Family

ID=71076370

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020560106A Active JP7608164B2 (ja) 2018-12-11 2019-12-10 抗体-薬物コンジュゲートとparp阻害剤の組み合わせ
JP2024221344A Pending JP2025041725A (ja) 2018-12-11 2024-12-18 抗体-薬物コンジュゲートとparp阻害剤の組み合わせ

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2020560106A Active JP7608164B2 (ja) 2018-12-11 2019-12-10 抗体-薬物コンジュゲートとparp阻害剤の組み合わせ

Country Status (11)

Country Link
US (1) US20220023436A1 (enExample)
EP (1) EP3909580A4 (enExample)
JP (2) JP7608164B2 (enExample)
KR (1) KR20210102341A (enExample)
CN (1) CN113271942A (enExample)
AU (1) AU2019396895B2 (enExample)
BR (1) BR112021011119A2 (enExample)
EA (1) EA202191641A1 (enExample)
SG (1) SG11202106248XA (enExample)
TW (1) TW202034959A (enExample)
WO (1) WO2020122034A1 (enExample)

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CA3142119A1 (en) * 2019-05-29 2020-12-03 Daiichi Sankyo Company, Limited Dosage of an antibody-drug conjugate for treating cancer
EP4225314A1 (en) * 2020-10-09 2023-08-16 AstraZeneca UK Limited Combination of antibody-drug conjugate and parp1 selective inhibitor
WO2022248268A1 (en) * 2021-05-28 2022-12-01 Adc Therapeutics Sa Combination therapy
US11806405B1 (en) 2021-07-19 2023-11-07 Zeno Management, Inc. Immunoconjugates and methods
WO2023089527A1 (en) 2021-11-18 2023-05-25 Astrazeneca Uk Limited Combination of antibody-drug conjugate and parp1 selective inhibitor
CN119317447A (zh) 2022-04-12 2025-01-14 米纳瓦生物技术公司 抗可变muc1*抗体及其用途
EP4531927A1 (en) * 2022-05-24 2025-04-09 Daiichi Sankyo Company, Limited Dosage regimen of an anti-cdh6 antibody-drug conjugate
CN120813389A (zh) * 2023-03-14 2025-10-17 第一三共株式会社 抗cdh6抗体-药物缀合物和vegf抑制剂的组合
CN120916791A (zh) * 2023-03-31 2025-11-07 第一三共株式会社 抗CDH6抗体-药物缀合物与HIF-2α抑制剂的组合
WO2024229406A1 (en) 2023-05-04 2024-11-07 Revolution Medicines, Inc. Combination therapy for a ras related disease or disorder
EP4495003A1 (en) 2023-07-20 2025-01-22 AIRBUS HELICOPTERS DEUTSCHLAND GmbH An external cargo adapter for use with a rotorcraft
US20250049810A1 (en) 2023-08-07 2025-02-13 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
US20250154171A1 (en) 2023-10-12 2025-05-15 Revolution Medicines, Inc. Ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
WO2025217307A1 (en) 2024-04-09 2025-10-16 Revolution Medicines, Inc. Methods for predicting response to a ras(on) inhibitor and combination therapies
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
WO2025255438A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder

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IL162181A (en) 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
CA2103059C (en) 1991-06-14 2005-03-22 Paul J. Carter Method for making humanized antibodies
PT1071700E (pt) 1998-04-20 2010-04-23 Glycart Biotechnology Ag Modificação por glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos
WO2000061739A1 (fr) 1999-04-09 2000-10-19 Kyowa Hakko Kogyo Co., Ltd. Methode de regulation de l'activite d'une molecule immunologiquement fonctionnelle
PL203326B1 (pl) 1999-06-25 2009-09-30 Genentech Inc Przeciwciało, kompozycja farmaceutyczna, koniugat, izolowany kwas nukleinowy, wektor, komórka gospodarza i sposób wytwarzania przeciwciała
MXPA03002974A (es) 2000-10-06 2004-05-05 Kyowa Hakko Kogyo Kk Celulas que producen composiciones de anticuerpo.
AR056857A1 (es) 2005-12-30 2007-10-24 U3 Pharma Ag Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos
CA2647632C (en) 2006-03-27 2017-06-27 University Of Maryland Biotechnology Institute Glycoprotein synthesis and remodeling by enzymatic transglycosylation
SI2716301T1 (sl) 2007-02-16 2017-07-31 Merrimack Pharmaceuticals, Inc. Protitelesa proti ErbB3 in uporaba le-teh
CN104220603B (zh) 2012-02-10 2017-06-06 马里兰大学,巴尔的摩 抗体及其Fc片段的化学酶法糖基化工程
KR102237639B1 (ko) 2012-10-11 2021-04-07 다이이찌 산쿄 가부시키가이샤 항체-약물 콘주게이트
ES2782248T3 (es) 2012-10-19 2020-09-11 Daiichi Sankyo Co Ltd Conjugado de anticuerpo y fármaco producido por la unión a través de un enlazador que tiene estructura hidrófila
IL320281A (en) * 2013-12-25 2025-06-01 Daiichi Sankyo Co Ltd Anti-trop2 antibodies and methods for producing same
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JP2017114763A (ja) 2014-03-26 2017-06-29 第一三共株式会社 抗cd98抗体−薬物コンジュゲート
DK3129063T3 (da) 2014-04-10 2021-04-06 Daiichi Sankyo Co Ltd Anti-her3-antistof-lægemiddelkonjugat
EP3130608B1 (en) 2014-04-10 2019-09-04 Daiichi Sankyo Co., Ltd. (anti-her2 antibody)-drug conjugate
US10195175B2 (en) * 2015-06-25 2019-02-05 Immunomedics, Inc. Synergistic effect of anti-Trop-2 antibody-drug conjugate in combination therapy for triple-negative breast cancer when used with microtubule inhibitors or PARP inhibitors
US11173213B2 (en) 2015-06-29 2021-11-16 Daiichi Sankyo Company, Limited Method for selectively manufacturing antibody-drug conjugate
EP3572428A4 (en) * 2017-01-17 2020-12-30 Daiichi Sankyo Company, Limited ANTI-BODY ANTI-GPR20 AND ANTI-BODY-DRUG CONJUGATE ANTI-GPR20
TW202530271A (zh) 2017-05-15 2025-08-01 日商第一三共股份有限公司 抗體-藥物結合物及其用途
KR20250084239A (ko) 2017-08-31 2025-06-10 다이이찌 산쿄 가부시키가이샤 항체-약물 콘주게이트의 개량 제조 방법

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