CN113271942A - 抗体-药物缀合物与parp抑制剂的组合 - Google Patents

抗体-药物缀合物与parp抑制剂的组合 Download PDF

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Publication number
CN113271942A
CN113271942A CN201980082698.7A CN201980082698A CN113271942A CN 113271942 A CN113271942 A CN 113271942A CN 201980082698 A CN201980082698 A CN 201980082698A CN 113271942 A CN113271942 A CN 113271942A
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antibody
amino acid
pharmaceutical composition
seq
acid sequence
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CN201980082698.7A
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Chinese (zh)
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扇谷祐辅
冈嶌大祐
桥本悠里
铃木宏和
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Daiichi Sankyo Co Ltd
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Daiichi Sankyo Co Ltd
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    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes

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  • Health & Medical Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201980082698.7A 2018-12-11 2019-12-10 抗体-药物缀合物与parp抑制剂的组合 Pending CN113271942A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2018231948 2018-12-11
JP2018-231948 2018-12-11
PCT/JP2019/048171 WO2020122034A1 (ja) 2018-12-11 2019-12-10 抗体－薬物コンジュゲートとｐａｒｐ阻害剤の組み合わせ

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CN113271942A true CN113271942A (zh) 2021-08-17

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US (1) US20220023436A1 (enExample)
EP (1) EP3909580A4 (enExample)
JP (2) JP7608164B2 (enExample)
KR (1) KR20210102341A (enExample)
CN (1) CN113271942A (enExample)
AU (1) AU2019396895B2 (enExample)
BR (1) BR112021011119A2 (enExample)
EA (1) EA202191641A1 (enExample)
SG (1) SG11202106248XA (enExample)
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WO (1) WO2020122034A1 (enExample)

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WO2022248268A1 (en) * 2021-05-28 2022-12-01 Adc Therapeutics Sa Combination therapy
US11806405B1 (en) 2021-07-19 2023-11-07 Zeno Management, Inc. Immunoconjugates and methods
WO2023089527A1 (en) 2021-11-18 2023-05-25 Astrazeneca Uk Limited Combination of antibody-drug conjugate and parp1 selective inhibitor
CN119317447A (zh) 2022-04-12 2025-01-14 米纳瓦生物技术公司 抗可变muc1*抗体及其用途
EP4531927A1 (en) * 2022-05-24 2025-04-09 Daiichi Sankyo Company, Limited Dosage regimen of an anti-cdh6 antibody-drug conjugate
CN120813389A (zh) * 2023-03-14 2025-10-17 第一三共株式会社 抗cdh6抗体-药物缀合物和vegf抑制剂的组合
CN120916791A (zh) * 2023-03-31 2025-11-07 第一三共株式会社 抗CDH6抗体-药物缀合物与HIF-2α抑制剂的组合
WO2024229406A1 (en) 2023-05-04 2024-11-07 Revolution Medicines, Inc. Combination therapy for a ras related disease or disorder
EP4495003A1 (en) 2023-07-20 2025-01-22 AIRBUS HELICOPTERS DEUTSCHLAND GmbH An external cargo adapter for use with a rotorcraft
US20250049810A1 (en) 2023-08-07 2025-02-13 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder
US20250154171A1 (en) 2023-10-12 2025-05-15 Revolution Medicines, Inc. Ras inhibitors
WO2025171296A1 (en) 2024-02-09 2025-08-14 Revolution Medicines, Inc. Ras inhibitors
WO2025217307A1 (en) 2024-04-09 2025-10-16 Revolution Medicines, Inc. Methods for predicting response to a ras(on) inhibitor and combination therapies
WO2025240847A1 (en) 2024-05-17 2025-11-20 Revolution Medicines, Inc. Ras inhibitors
WO2025255438A1 (en) 2024-06-07 2025-12-11 Revolution Medicines, Inc. Methods of treating a ras protein-related disease or disorder

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