JP2025023947A5 - - Google Patents

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JP2025023947A5
JP2025023947A5 JP2024187194A JP2024187194A JP2025023947A5 JP 2025023947 A5 JP2025023947 A5 JP 2025023947A5 JP 2024187194 A JP2024187194 A JP 2024187194A JP 2024187194 A JP2024187194 A JP 2024187194A JP 2025023947 A5 JP2025023947 A5 JP 2025023947A5
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seq
expression construct
sequence
composition
copies
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JP2024187194A
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Japanese (ja)
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JP7829658B2 (ja
JP2025023947A (ja
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Priority claimed from PCT/US2019/054539 external-priority patent/WO2020076614A1/en
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JP2024187194A 2018-10-08 2024-10-24 介在ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 Active JP7829658B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2026032511A JP2026094314A (ja) 2018-10-08 2026-03-02 介在ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201862742835P 2018-10-08 2018-10-08
US62/742,835 2018-10-08
US201862749012P 2018-10-22 2018-10-22
US62/749,012 2018-10-22
US201962810281P 2019-02-25 2019-02-25
US62/810,281 2019-02-25
PCT/US2019/054539 WO2020076614A1 (en) 2018-10-08 2019-10-03 Artificial expression constructs for selectively modulating gene expression in interneurons
JP2021543981A JP7695192B2 (ja) 2018-10-08 2019-10-03 介在ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物

Related Parent Applications (1)

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JP2021543981A Division JP7695192B2 (ja) 2018-10-08 2019-10-03 介在ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物

Related Child Applications (1)

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JP2026032511A Division JP2026094314A (ja) 2018-10-08 2026-03-02 介在ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物

Publications (3)

Publication Number Publication Date
JP2025023947A JP2025023947A (ja) 2025-02-19
JP2025023947A5 true JP2025023947A5 (enExample) 2025-07-08
JP7829658B2 JP7829658B2 (ja) 2026-03-13

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JP2021543981A Active JP7695192B2 (ja) 2018-10-08 2019-10-03 介在ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物
JP2024187194A Active JP7829658B2 (ja) 2018-10-08 2024-10-24 介在ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物
JP2026032511A Pending JP2026094314A (ja) 2018-10-08 2026-03-02 介在ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物

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JP2021543981A Active JP7695192B2 (ja) 2018-10-08 2019-10-03 介在ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物

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JP2026032511A Pending JP2026094314A (ja) 2018-10-08 2026-03-02 介在ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物

Country Status (6)

Country Link
US (2) US12467064B2 (enExample)
EP (1) EP3864150A4 (enExample)
JP (3) JP7695192B2 (enExample)
AU (2) AU2019358806B2 (enExample)
CA (1) CA3115652A1 (enExample)
WO (1) WO2020076614A1 (enExample)

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EP3781174A4 (en) 2018-04-09 2022-01-26 Allen Institute RESCUE OF VOLTAGE CONTROLLED SODIUM CHANNEL FUNCTION IN INHIBITORY NEURONS
US12467064B2 (en) * 2018-10-08 2025-11-11 Allen Institute Artificial expression constructs for selectively modulating gene expression in interneurons
JP7721568B2 (ja) * 2020-04-21 2025-08-12 アレン インスティテュート 新皮質層５グルタミン酸作動性ニューロンにおいて遺伝子発現を選択的に調節する人工発現構築物
WO2021248085A2 (en) 2020-06-04 2021-12-09 Allen Institute Artificial expression constructs for selectively modulating gene expression in inhibitory neocortical neurons
US20230302158A1 (en) * 2020-08-14 2023-09-28 Allen Institute Artificial expression constructs for modulating gene expression in striatal neurons
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WO2022169884A2 (en) * 2021-02-02 2022-08-11 Allen Institute Artificial expression constructs for modulating gene expression in gabaergic neurons and astrocytes
CN116286917A (zh) * 2021-12-14 2023-06-23 中国科学院深圳先进技术研究院 重组载体及其构建方法和应用
EP4536835A2 (en) * 2022-06-13 2025-04-16 Allen Institute Artificial expression constructs for modulating gene expression in non-neuronal central nervous system cells
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CN119060958A (zh) * 2023-12-15 2024-12-03 中国科学院深圳先进技术研究院 一种携带钙离子报告基因的神经元及其制备方法和应用

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US12467064B2 (en) * 2018-10-08 2025-11-11 Allen Institute Artificial expression constructs for selectively modulating gene expression in interneurons

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