JP2026021360A5 - - Google Patents
Info
- Publication number
- JP2026021360A5 JP2026021360A5 JP2025175276A JP2025175276A JP2026021360A5 JP 2026021360 A5 JP2026021360 A5 JP 2026021360A5 JP 2025175276 A JP2025175276 A JP 2025175276A JP 2025175276 A JP2025175276 A JP 2025175276A JP 2026021360 A5 JP2026021360 A5 JP 2026021360A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- sequence shown
- nucleic acid
- neurons
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862755988P | 2018-11-05 | 2018-11-05 | |
| US62/755,988 | 2018-11-05 | ||
| US201962806684P | 2019-02-15 | 2019-02-15 | |
| US201962806600P | 2019-02-15 | 2019-02-15 | |
| US62/806,684 | 2019-02-15 | ||
| US62/806,600 | 2019-02-15 | ||
| US201962872021P | 2019-07-09 | 2019-07-09 | |
| US62/872,021 | 2019-07-09 | ||
| JP2021523074A JP7590962B2 (ja) | 2018-11-05 | 2019-11-05 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| PCT/US2019/059927 WO2020097121A1 (en) | 2018-11-05 | 2019-11-05 | Artificial expression constructs for selectively modulating gene expression in excitatory cortical neurons |
| JP2024198841A JP7774695B2 (ja) | 2018-11-05 | 2024-11-14 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024198841A Division JP7774695B2 (ja) | 2018-11-05 | 2024-11-14 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2026021360A JP2026021360A (ja) | 2026-02-10 |
| JP2026021360A5 true JP2026021360A5 (enExample) | 2026-04-02 |
Family
ID=70612483
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021523074A Active JP7590962B2 (ja) | 2018-11-05 | 2019-11-05 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| JP2024198841A Active JP7774695B2 (ja) | 2018-11-05 | 2024-11-14 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| JP2025175276A Pending JP2026021360A (ja) | 2018-11-05 | 2025-10-17 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021523074A Active JP7590962B2 (ja) | 2018-11-05 | 2019-11-05 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| JP2024198841A Active JP7774695B2 (ja) | 2018-11-05 | 2024-11-14 | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US12703873B2 (enExample) |
| EP (1) | EP3877529A4 (enExample) |
| JP (3) | JP7590962B2 (enExample) |
| AU (2) | AU2019375975B2 (enExample) |
| CA (1) | CA3118689A1 (enExample) |
| WO (1) | WO2020097121A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7590962B2 (ja) | 2018-11-05 | 2024-11-27 | アレン インスティテュート | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| CA3142948A1 (en) | 2019-02-15 | 2020-08-20 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in selected neuronal cell populations |
| CN113710693B (zh) | 2019-02-25 | 2025-07-15 | 马萨诸塞大学 | Dna结合结构域反式激活因子及其用途 |
| WO2021248085A2 (en) * | 2020-06-04 | 2021-12-09 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in inhibitory neocortical neurons |
| EP4185303A4 (en) * | 2020-07-24 | 2024-10-30 | University of Massachusetts | Dna-binding domain transactivators and uses thereof |
| US20230302158A1 (en) * | 2020-08-14 | 2023-09-28 | Allen Institute | Artificial expression constructs for modulating gene expression in striatal neurons |
| GB202013940D0 (en) | 2020-09-04 | 2020-10-21 | Synpromics Ltd | Regulatory nucleic acid sequences |
| EP4244366A4 (en) * | 2020-11-10 | 2024-12-25 | Allen Institute | Artificial expression constructs for modulating gene expression in chandelier cells |
| EP4277524A4 (en) * | 2021-01-13 | 2025-06-04 | Duke University | Compositions for and methods of improving fluid flux in the brain |
| US20240182923A1 (en) * | 2021-03-30 | 2024-06-06 | Allen Institute | Artificial expression constructs for modulating gene expression in claustrum neurons |
| AU2022276538A1 (en) * | 2021-05-21 | 2023-11-09 | Allen Institute | Artificial expression constructs for modulating gene expression in neurons within the thalamus |
| CN113736734B (zh) * | 2021-09-23 | 2022-10-25 | 中山大学中山眼科中心 | 一种用于灵长类动物神经元分离的试剂盒及方法 |
| WO2023108021A1 (en) * | 2021-12-07 | 2023-06-15 | Allen Institute | Artificial expression constructs for modulating gene expression in neocortical layer 4 or layer 5 intratelencephalic neurons |
| AU2023226080A1 (en) * | 2022-02-24 | 2024-10-03 | Allen Institute | Artificial expression constructs for modulating gene expression in dopaminergic neurons |
| CN114752624B (zh) * | 2022-04-08 | 2025-04-15 | 中国海洋大学 | 一种侏儒蛤卵子的电穿孔方法 |
| WO2024011224A2 (en) * | 2022-07-08 | 2024-01-11 | The Trustees Of Columbia University In The City Of New York | Regulatory element for cell type specific expression of genes in spinal motor neurons |
| WO2024238448A2 (en) * | 2023-05-12 | 2024-11-21 | Temple University - Of The Commonwealth System Of Higher Education | Chimeric capsid recombinant adeno-associated virus with bbb penetration and microglia targeting (aav-bm) |
| CN117346715B (zh) * | 2023-12-04 | 2024-03-08 | 成都深瑞同华科技有限公司 | 一种配电网架空线路弧垂测定方法、系统及存储介质 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5549910A (en) | 1989-03-31 | 1996-08-27 | The Regents Of The University Of California | Preparation of liposome and lipid complex compositions |
| JP3218637B2 (ja) | 1990-07-26 | 2001-10-15 | 大正製薬株式会社 | 安定なリポソーム水懸濁液 |
| JP2958076B2 (ja) | 1990-08-27 | 1999-10-06 | 株式会社ビタミン研究所 | 遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法 |
| US5795587A (en) | 1995-01-23 | 1998-08-18 | University Of Pittsburgh | Stable lipid-comprising drug delivery complexes and methods for their production |
| US5738868A (en) | 1995-07-18 | 1998-04-14 | Lipogenics Ltd. | Liposome compositions and kits therefor |
| DE69918090T2 (de) | 1998-04-24 | 2005-06-16 | University Of Florida, Gainesville | Rekombinanter adeno-assoziierter viraler vektor, der alpha-1 antitrypsin kodiert, zur gentherapie |
| US20070037165A1 (en) | 2000-09-08 | 2007-02-15 | Applera Corporation | Polymorphisms in known genes associated with human disease, methods of detection and uses thereof |
| EP1430114B1 (en) | 2001-09-14 | 2012-01-18 | Stem Cell Therapeutics Inc. | Prolactin induced increase in neural stem cell numbers and therapeutical use thereof |
| EP2028268A1 (en) * | 2007-08-20 | 2009-02-25 | Université Libre De Bruxelles | Generation of neuronal cells from pluripotent stem cells |
| EP3702460A1 (en) | 2010-11-12 | 2020-09-02 | The General Hospital Corporation | Polycomb-associated non-coding rnas |
| US20120308530A1 (en) | 2011-06-03 | 2012-12-06 | Beijing Allgens Medical Science & Technology Co., Ltd. | Materials Composition and Methods to Control Neural Progenitor and Stem Cell Attachment, Proliferation and Guide Cell Differentiation |
| US9284575B2 (en) | 2012-03-06 | 2016-03-15 | Duke University | Synthetic regulation of gene expression |
| WO2013155222A2 (en) | 2012-04-10 | 2013-10-17 | The Regents Of The University Of California | Brain-specific enhancers for cell-based therapy |
| US9579399B2 (en) | 2012-08-27 | 2017-02-28 | Friedrich Miescher Institute For Biomedical Research | Retinal OFF circuit-specific promoter |
| EP2922972B1 (en) * | 2012-11-26 | 2017-04-26 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Colorectal cancer classification with differential prognosis and personalized therapeutic responses |
| US20150376612A1 (en) | 2014-06-10 | 2015-12-31 | The General Hospital Corporation | CCCTC-Binding Factor (CTCF) RNA Interactome |
| CL2014003590A1 (es) * | 2014-12-30 | 2015-07-10 | Univ Chile | Virus aav/xbp1s-ha, método de tratamiento genético y su uso en la optimizacion y mejoramiento de las capacidades cognitivas, de memoria y de aprendizaje. |
| US10682424B2 (en) | 2015-03-31 | 2020-06-16 | New York University | Compositions and method for reducing seizures |
| US9790490B2 (en) | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
| AU2016366549B2 (en) | 2015-12-11 | 2022-11-10 | California Institute Of Technology | Targeting peptides for directing adeno-associated viruses (AAVs) |
| EP3416663B1 (en) | 2016-02-18 | 2021-04-14 | The Penn State Research Foundation | Generating gabaergic neurons in brains |
| CN117821509A (zh) * | 2017-04-03 | 2024-04-05 | 编码治疗公司 | 组织选择性转基因表达 |
| JP7590962B2 (ja) | 2018-11-05 | 2024-11-27 | アレン インスティテュート | 皮質興奮性ニューロンにおける遺伝子発現を選択的に調節するための人工発現構築物 |
| CA3142948A1 (en) | 2019-02-15 | 2020-08-20 | Allen Institute | Artificial expression constructs for selectively modulating gene expression in selected neuronal cell populations |
-
2019
- 2019-11-05 JP JP2021523074A patent/JP7590962B2/ja active Active
- 2019-11-05 CA CA3118689A patent/CA3118689A1/en active Pending
- 2019-11-05 EP EP19881101.0A patent/EP3877529A4/en active Pending
- 2019-11-05 US US17/291,584 patent/US12703873B2/en active Active
- 2019-11-05 AU AU2019375975A patent/AU2019375975B2/en active Active
- 2019-11-05 WO PCT/US2019/059927 patent/WO2020097121A1/en not_active Ceased
-
2024
- 2024-11-14 JP JP2024198841A patent/JP7774695B2/ja active Active
- 2024-12-31 US US19/007,263 patent/US20250236886A1/en active Pending
-
2025
- 2025-10-02 AU AU2025242185A patent/AU2025242185A1/en active Pending
- 2025-10-17 JP JP2025175276A patent/JP2026021360A/ja active Pending
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