JP2022552003A5 - - Google Patents

Info

Publication number
JP2022552003A5
JP2022552003A5 JP2022522966A JP2022522966A JP2022552003A5 JP 2022552003 A5 JP2022552003 A5 JP 2022552003A5 JP 2022522966 A JP2022522966 A JP 2022522966A JP 2022522966 A JP2022522966 A JP 2022522966A JP 2022552003 A5 JP2022552003 A5 JP 2022552003A5
Authority
JP
Japan
Prior art keywords
nucleic acid
biologically active
active fragment
exogenous nucleic
polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022522966A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022552003A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/056108 external-priority patent/WO2021076983A1/en
Publication of JP2022552003A publication Critical patent/JP2022552003A/ja
Publication of JP2022552003A5 publication Critical patent/JP2022552003A5/ja
Priority to JP2025124068A priority Critical patent/JP2025184866A/ja
Pending legal-status Critical Current

Links

JP2022522966A 2019-10-17 2020-10-16 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生 Pending JP2022552003A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025124068A JP2025184866A (ja) 2019-10-17 2025-07-24 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962916713P 2019-10-17 2019-10-17
US62/916,713 2019-10-17
US202063040989P 2020-06-18 2020-06-18
US63/040,989 2020-06-18
PCT/US2020/056108 WO2021076983A1 (en) 2019-10-17 2020-10-16 Regenerating functional neurons for treatment of spinal cord injury and als

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025124068A Division JP2025184866A (ja) 2019-10-17 2025-07-24 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生

Publications (2)

Publication Number Publication Date
JP2022552003A JP2022552003A (ja) 2022-12-14
JP2022552003A5 true JP2022552003A5 (enExample) 2023-10-20

Family

ID=75538363

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022522966A Pending JP2022552003A (ja) 2019-10-17 2020-10-16 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生
JP2025124068A Pending JP2025184866A (ja) 2019-10-17 2025-07-24 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025124068A Pending JP2025184866A (ja) 2019-10-17 2025-07-24 脊髄損傷およびａｌｓの治療のための機能的ニューロンの再生

Country Status (7)

Country Link
US (2) US20210162002A1 (enExample)
EP (1) EP4045148A4 (enExample)
JP (2) JP2022552003A (enExample)
CN (2) CN114364436A (enExample)
AU (1) AU2020365130B2 (enExample)
CA (1) CA3157523A1 (enExample)
WO (1) WO2021076983A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2023003655A (es) 2020-09-29 2023-06-22 Neuexcell Therapeutics Inc Vector neurod1.
TW202541819A (zh) * 2023-12-27 2025-11-01 日商安斯泰來製藥股份有限公司 脊髓損傷之治療用醫藥組成物及脊髓損傷之非人類靈長類動物模式之製作方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2658180A1 (en) * 2006-07-19 2008-01-31 University Of Florida Research Foundation, Inc. Compositions for reprogramming a cell and uses therefor
WO2013025963A2 (en) * 2011-08-17 2013-02-21 President And Fellows Of Harvard College Conversion of somatic cells into functional spinal motor neurons, and methods and uses thereof
CN113559282A (zh) * 2012-07-19 2021-10-29 宾夕法尼亚州研究基金会 再生用于在神经系统中治疗疾病和损伤的功能性神经元
SG11201507829SA (en) * 2013-03-21 2015-12-30 Univ Kyoto Pluripotent stem cell for neuronal differentiation induction
US20160115447A1 (en) * 2013-06-11 2016-04-28 President And Fellows Of Harvard College Compositions and methods for improving induced neuron generation
KR102113829B1 (ko) * 2013-10-25 2020-05-25 웨인 스테이트 유니버시티 단백질-유도 생체내 세포 재프로그래밍을 통한 세포 전환 방법, 시스템 및 조성물
WO2016086092A1 (en) * 2014-11-25 2016-06-02 The Penn State Research Foundation Chemical reprogramming of human glial cells into neurons for brain and spinal cord repair
AU2016366549B2 (en) * 2015-12-11 2022-11-10 California Institute Of Technology Targeting peptides for directing adeno-associated viruses (AAVs)
EP3416663B1 (en) * 2016-02-18 2021-04-14 The Penn State Research Foundation Generating gabaergic neurons in brains
IT201600093825A1 (it) * 2016-09-19 2018-03-19 Fondazione St Italiano Tecnologia Composizione farmaceutica di miRNA e suoi usi terapeutici.
EP4039812B1 (en) * 2017-02-28 2025-06-11 The Penn State Research Foundation Regenerating functional neurons for treatment of neural injury caused by disruption of blood flow
US20200377885A1 (en) * 2017-08-07 2020-12-03 Washington University Compositions and methods for the generation of neurons and uses thereof
EP4221761A4 (en) * 2020-09-29 2025-02-26 Neuexcell Therapeutics Inc. Neurod1 combination vector

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