JP2019537437A5 - - Google Patents
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- JP2019537437A5 JP2019537437A5 JP2019522550A JP2019522550A JP2019537437A5 JP 2019537437 A5 JP2019537437 A5 JP 2019537437A5 JP 2019522550 A JP2019522550 A JP 2019522550A JP 2019522550 A JP2019522550 A JP 2019522550A JP 2019537437 A5 JP2019537437 A5 JP 2019537437A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- cell
- isolated nucleic
- vector
- expression cassette
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16196818 | 2016-11-02 | ||
| EP16196818.5 | 2016-11-02 | ||
| PCT/IB2017/056792 WO2018083607A1 (en) | 2016-11-02 | 2017-11-01 | Synp198, a promoter for the specific expression of genes in direction selective retinal ganglion cells |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019537437A JP2019537437A (ja) | 2019-12-26 |
| JP2019537437A5 true JP2019537437A5 (enExample) | 2020-12-10 |
| JP7023279B2 JP7023279B2 (ja) | 2022-02-21 |
Family
ID=57223559
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019522550A Expired - Fee Related JP7023279B2 (ja) | 2016-11-02 | 2017-11-01 | ＳｙｎＰ１９８、方向選択性網膜神経節細胞内での遺伝子の特異的発現のためのプロモーター |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US11525145B2 (enExample) |
| EP (1) | EP3534966B1 (enExample) |
| JP (1) | JP7023279B2 (enExample) |
| KR (1) | KR20190077471A (enExample) |
| CN (1) | CN110072557B (enExample) |
| AU (1) | AU2017354086C1 (enExample) |
| BR (1) | BR112019008488A2 (enExample) |
| CA (1) | CA3042197A1 (enExample) |
| IL (1) | IL266115A (enExample) |
| RU (1) | RU2766353C2 (enExample) |
| WO (1) | WO2018083607A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2679246A3 (en) | 2008-04-18 | 2014-02-26 | Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research | Novel therapeutical tools and methods for treating blindness |
| WO2016174624A1 (en) | 2015-04-30 | 2016-11-03 | Friedrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in müller cells |
| WO2017046084A1 (en) | 2015-09-15 | 2017-03-23 | Friedrich Miescher Institute For Biomedical Research | Novel therapeutical tools and methods for treating blindness by targeting photoreceptors |
| ES2881782T3 (es) | 2015-10-14 | 2021-11-30 | Friedrich Miescher Institute For Biomedical Res | Promotor para la expresión específica de genes en células endoteliales retinianas. |
| US10898586B2 (en) | 2015-12-03 | 2021-01-26 | Friedrich Miescher Institute For Biomedical Research | SynP161, a promoter for the specific expression of genes in rod photoreceptors |
| JP7058220B2 (ja) | 2015-12-03 | 2022-04-21 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | ＳｙｎＰ１５９、桿体光受容器における遺伝子の特異的発現のためのプロモーター |
| US10994026B2 (en) | 2015-12-03 | 2021-05-04 | Friedrich Miescher Institute For Biomedical Research | SynP160, a promoter for the specific expression of genes in rod photoreceptors |
| US11059871B2 (en) | 2015-12-03 | 2021-07-13 | Friedrich Miescher Institute For Biomedical Research | SYNP162, a promoter for the specific expression of genes in rod photoreceptors |
| WO2018083607A1 (en) | 2016-11-02 | 2018-05-11 | Friedrich Miescher Institute For Biomedical Research | Synp198, a promoter for the specific expression of genes in direction selective retinal ganglion cells |
| JP7112414B2 (ja) | 2017-02-08 | 2022-08-03 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | 網膜神経節細胞中の遺伝子の特異的発現のためのプロモーターｓｙｎｐ８８ |
| WO2019097454A1 (en) | 2017-11-15 | 2019-05-23 | Friedrich Miescher Institute For Biomedical Research | Primate retinal pigment epithelium cell-specific promoter |
| US11591615B2 (en) | 2017-11-30 | 2023-02-28 | Friedrich Miescher Institute For Biomedical Research | SynPIII, a promoter for the specific expression of genes in retinal pigment epithelium |
| CN112930200A (zh) * | 2018-10-25 | 2021-06-08 | 弗里德里克·米谢尔生物医学研究所 | 用于视网膜神经节细胞中特异表达基因的启动子SynP151(ProC29) |
| JP7895637B2 (ja) * | 2021-02-22 | 2026-07-28 | ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト | 眼病態に対するウイルスベクターベースの遺伝子療法 |
Family Cites Families (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8470790B2 (en) * | 2006-05-04 | 2013-06-25 | Wayne State University | Restoration of visual responses by in vivo delivery of rhodopsin nucleic acids |
| EP1891976A1 (en) | 2006-08-23 | 2008-02-27 | Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute for Biomedical Research | Use of light sensitive genes |
| EP2679246A3 (en) * | 2008-04-18 | 2014-02-26 | Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute For Biomedical Research | Novel therapeutical tools and methods for treating blindness |
| ES2563984T3 (es) * | 2008-10-22 | 2016-03-17 | Quark Pharmaceuticals, Inc. | Métodos para el tratamiento de trastornos oculares |
| WO2013068413A1 (en) * | 2011-11-08 | 2013-05-16 | Novartis Forschungsstiftung, Zweigniederlassung, Friedrich Miescher Institute For Biomedical Research | Rod cell-specific promoter |
| US9579399B2 (en) | 2012-08-27 | 2017-02-28 | Friedrich Miescher Institute For Biomedical Research | Retinal OFF circuit-specific promoter |
| EP2996725A4 (en) * | 2013-05-16 | 2016-12-28 | Applied Genetic Tech Corp | PROMOTERS, EXPRESSION CASSETTES, VECTORS, KITS AND METHODS FOR TREATING COLOR BLINDNESS AND OTHER PROBLEMS |
| US9862970B2 (en) | 2013-06-11 | 2018-01-09 | Friedrich Miescher Institute For Biomedical Research | Retinal on bipolar cells-specific artificial promoter |
| WO2015118507A1 (en) | 2014-02-10 | 2015-08-13 | Friedrich Miescher Institute For Biomedical Research | Aii retinal amacrine cell-specific promoter |
| WO2015121793A1 (en) | 2014-02-11 | 2015-08-20 | Friedrich Miescher Institute For Biomedical Research | Müller cell-specific promoter |
| WO2016174624A1 (en) | 2015-04-30 | 2016-11-03 | Friedrich Miescher Institute For Biomedical Research | Promoter for the specific expression of genes in müller cells |
| WO2017046084A1 (en) | 2015-09-15 | 2017-03-23 | Friedrich Miescher Institute For Biomedical Research | Novel therapeutical tools and methods for treating blindness by targeting photoreceptors |
| ES2881782T3 (es) | 2015-10-14 | 2021-11-30 | Friedrich Miescher Institute For Biomedical Res | Promotor para la expresión específica de genes en células endoteliales retinianas. |
| US11059871B2 (en) | 2015-12-03 | 2021-07-13 | Friedrich Miescher Institute For Biomedical Research | SYNP162, a promoter for the specific expression of genes in rod photoreceptors |
| US10898586B2 (en) | 2015-12-03 | 2021-01-26 | Friedrich Miescher Institute For Biomedical Research | SynP161, a promoter for the specific expression of genes in rod photoreceptors |
| US10994026B2 (en) | 2015-12-03 | 2021-05-04 | Friedrich Miescher Institute For Biomedical Research | SynP160, a promoter for the specific expression of genes in rod photoreceptors |
| JP7058220B2 (ja) | 2015-12-03 | 2022-04-21 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | ＳｙｎＰ１５９、桿体光受容器における遺伝子の特異的発現のためのプロモーター |
| JP6966442B2 (ja) | 2015-12-04 | 2021-11-17 | ソルボンヌ・ユニヴェルシテSorbonne Universite | プロモーター及びその使用 |
| EP3458476A1 (en) | 2016-05-17 | 2019-03-27 | Friedrich Miescher Institute for Biomedical Research | Novel therapeutic tools and methods for treating blindness |
| WO2018083607A1 (en) | 2016-11-02 | 2018-05-11 | Friedrich Miescher Institute For Biomedical Research | Synp198, a promoter for the specific expression of genes in direction selective retinal ganglion cells |
| WO2018099974A1 (en) | 2016-12-01 | 2018-06-07 | Friedrich Miescher Institute For Biomedical Research | Synp107, a promoter for the specific expression of genes in interneurons |
| JP2020501538A (ja) | 2016-12-01 | 2020-01-23 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | インターニューロン中の遺伝子の特異的発現のためのプロモーターｓｙｎｐｉ |
| JP7112414B2 (ja) | 2017-02-08 | 2022-08-03 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | 網膜神経節細胞中の遺伝子の特異的発現のためのプロモーターｓｙｎｐ８８ |
| WO2019097454A1 (en) | 2017-11-15 | 2019-05-23 | Friedrich Miescher Institute For Biomedical Research | Primate retinal pigment epithelium cell-specific promoter |
| CR20200235A (es) | 2017-11-30 | 2020-10-19 | Friedrich Miescher Institute For Biomedical Res | Synp61, un promotor específico de células del epitelio pigmentario retiniano de primates |
| US11591615B2 (en) | 2017-11-30 | 2023-02-28 | Friedrich Miescher Institute For Biomedical Research | SynPIII, a promoter for the specific expression of genes in retinal pigment epithelium |
| CN112912508A (zh) | 2018-10-25 | 2021-06-04 | 弗里德里克·米谢尔生物医学研究所 | 用于使基因在视网膜神经节细胞中特异性表达的启动子SynP194(ProB15) |
| CN112930200A (zh) | 2018-10-25 | 2021-06-08 | 弗里德里克·米谢尔生物医学研究所 | 用于视网膜神经节细胞中特异表达基因的启动子SynP151(ProC29) |
| US20210388385A1 (en) | 2018-10-25 | 2021-12-16 | Friedrich Miescher Institute For Biomedical Research | Synp27 (prob12), a promoter for the specific expression of genes in protoplasmic astrocytes |
| WO2020084537A1 (en) | 2018-10-25 | 2020-04-30 | Friedrich Miescher Institute For Biomedical Research | Synp17 (prob1), a promoter for the specific expression of genes in retinal ganglion cells |
| EP3870239A1 (en) | 2018-10-25 | 2021-09-01 | Friedrich Miescher Institute for Biomedical Research | Synp57 (proa14), a promoter for the specific expression of genes in photoreceptors |
| JP2022512784A (ja) | 2018-10-25 | 2022-02-07 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | 網膜神経節細胞中の遺伝子の特異的発現のためのプロモーターＳｙｎＰ７８（ＰｒｏＡ２７） |
| WO2020152626A1 (en) | 2019-01-24 | 2020-07-30 | Friedrich Miescher Institute For Biomedical Research | Synp166 (proa36), a promoter for the specific expression of genes in photoreceptors |
| WO2020152623A1 (en) | 2019-01-24 | 2020-07-30 | Friedrich Miescher Institute For Biomedical Research | Synp5 (proa9), a promoter for the specific expression of genes in retinal ganglion cells |
| JP2022517688A (ja) | 2019-01-24 | 2022-03-09 | フリードリッヒ ミーシェー インスティトゥート フォー バイオメディカル リサーチ | 網膜神経節細胞中の遺伝子の特異的発現のためのプロモーターＳｙｎＰ３５（ＰｒｏＣ８） |
| EP3914300A1 (en) | 2019-01-24 | 2021-12-01 | Friedrich Miescher Institute for Biomedical Research | Synp66 (proa21), a promoter for the specific expression of genes in retinal ganglion cells |
| US20220154210A1 (en) | 2019-02-25 | 2022-05-19 | Novartis Ag | Compositions and methods to treat bietti crystalline dystrophy |
| EP3931335A2 (en) | 2019-02-25 | 2022-01-05 | Novartis AG | Compositions and methods to treat bietti crystalline dystrophy |
-
2017
- 2017-11-01 WO PCT/IB2017/056792 patent/WO2018083607A1/en not_active Ceased
- 2017-11-01 RU RU2019115117A patent/RU2766353C2/ru active
- 2017-11-01 KR KR1020197015426A patent/KR20190077471A/ko not_active Ceased
- 2017-11-01 US US16/346,680 patent/US11525145B2/en active Active
- 2017-11-01 EP EP17811378.3A patent/EP3534966B1/en active Active
- 2017-11-01 JP JP2019522550A patent/JP7023279B2/ja not_active Expired - Fee Related
- 2017-11-01 AU AU2017354086A patent/AU2017354086C1/en not_active Ceased
- 2017-11-01 BR BR112019008488A patent/BR112019008488A2/pt not_active Application Discontinuation
- 2017-11-01 CN CN201780067090.8A patent/CN110072557B/zh not_active Expired - Fee Related
- 2017-11-01 CA CA3042197A patent/CA3042197A1/en not_active Abandoned
-
2019
- 2019-04-17 IL IL266115A patent/IL266115A/en unknown
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