JP2024543451A - プロテインチロシンホスファターゼ阻害剤及びその使用方法 - Google Patents

プロテインチロシンホスファターゼ阻害剤及びその使用方法 Download PDF

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Publication number
JP2024543451A
JP2024543451A JP2024527749A JP2024527749A JP2024543451A JP 2024543451 A JP2024543451 A JP 2024543451A JP 2024527749 A JP2024527749 A JP 2024527749A JP 2024527749 A JP2024527749 A JP 2024527749A JP 2024543451 A JP2024543451 A JP 2024543451A
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JP
Japan
Prior art keywords
fluoro
benzothiopyran
dihydro
hydroxy
amino
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Pending
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JP2024527749A
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English (en)
Japanese (ja)
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JP2024543451A5 (https=
Inventor
アンドリュー ボグダン
クリストス エコノム
ジェニファー エム． フロスト
フィリップ アール． キム
スペンサー オー． ショルツ
チャオミン ション
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AbbVie Inc
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AbbVie Inc
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Application filed by AbbVie Inc filed Critical AbbVie Inc
Publication of JP2024543451A publication Critical patent/JP2024543451A/ja
Publication of JP2024543451A5 publication Critical patent/JP2024543451A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433—Thidiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2024527749A 2021-11-11 2022-11-10 プロテインチロシンホスファターゼ阻害剤及びその使用方法 Pending JP2024543451A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163278336P 2021-11-11 2021-11-11
US63/278,336 2021-11-11
PCT/US2022/049581 WO2023086495A1 (en) 2021-11-11 2022-11-10 Protein tyrosine phosphatase inhibitors and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2024543451A true JP2024543451A (ja) 2024-11-21
JP2024543451A5 JP2024543451A5 (https=) 2025-11-17

Family

ID=84887566

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024527749A Pending JP2024543451A (ja) 2021-11-11 2022-11-10 プロテインチロシンホスファターゼ阻害剤及びその使用方法

Country Status (8)

Country Link
US (1) US20250042894A1 (https=)
EP (1) EP4430039A1 (https=)
JP (1) JP2024543451A (https=)
CN (1) CN118556055A (https=)
AU (1) AU2022386164A1 (https=)
CA (1) CA3236853A1 (https=)
MX (1) MX2024005656A (https=)
WO (1) WO2023086495A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20252789A1 (es) 2023-05-24 2025-12-22 Kumquat Biosciences Inc Compuestos heterociclicos y usos de estos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA94921C2 (en) * 2005-12-08 2011-06-25 Новартис Аг 1-orthofluorophenyl substituted 1, 2, 5-thiazolidinedione derivatives as ptp-as inhibitors
BR112020026086A2 (pt) * 2018-06-21 2021-03-23 Calico Life Sciences Llc inibidores da proteína tirosina fosfatase e métodos de uso destes
IL286373B2 (en) * 2019-03-14 2026-03-01 Calico Life Sciences Llc Protein tyrosine phosphate inhibitor compounds and uses thereof
CA3162069A1 (en) * 2019-12-18 2021-06-24 Elliot P. Farney Protein tyrosine phosphatase inhibitors and methods of use thereof

Also Published As

Publication number Publication date
US20250042894A1 (en) 2025-02-06
AU2022386164A1 (en) 2024-05-23
MX2024005656A (es) 2024-08-06
CA3236853A1 (en) 2023-05-19
EP4430039A1 (en) 2024-09-18
WO2023086495A1 (en) 2023-05-19
CN118556055A (zh) 2024-08-27

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