JP2024542881A - Ｋｖ７．２阻害剤としての新規ヘテロアリール－尿素化合物 - Google Patents

Ｋｖ７．２阻害剤としての新規ヘテロアリール－尿素化合物 Download PDF

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JP2024542881A
JP2024542881A JP2024529786A JP2024529786A JP2024542881A JP 2024542881 A JP2024542881 A JP 2024542881A JP 2024529786 A JP2024529786 A JP 2024529786A JP 2024529786 A JP2024529786 A JP 2024529786A JP 2024542881 A JP2024542881 A JP 2024542881A
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Japan
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alkyl
membered
cycloalkyl
alkoxy
compound
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JP2024529786A
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JP2024542881A5 (https=
Inventor
チャップマン，マーク
デービッドソン，ジェームス
ディビス，ニコラス・ガレス，モールス
ゲルラッハ，アーロン
グラハム，クリストファー，ジョン
ルブルトン，シルバン
リ，ロンファ
マ，ニナ
メチン，イングリッド
マウリー，デイヴィッド
ナガラジャン，カールティゲヤン
ナイル，アニル
ノークロス，ロジャー・ディヴィッド
レドンド・ペナ，ロジェ・リュイ
サファロヴァ，アリョーナ
スミュルチナ，マーティン
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F Hoffmann La Roche AG
Icagen LLC
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F Hoffmann La Roche AG
Icagen LLC
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Publication of JP2024542881A publication Critical patent/JP2024542881A/ja
Publication of JP2024542881A5 publication Critical patent/JP2024542881A5/ja
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    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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