JP2024540642A5 - - Google Patents

Info

Publication number
JP2024540642A5
JP2024540642A5 JP2024530488A JP2024530488A JP2024540642A5 JP 2024540642 A5 JP2024540642 A5 JP 2024540642A5 JP 2024530488 A JP2024530488 A JP 2024530488A JP 2024530488 A JP2024530488 A JP 2024530488A JP 2024540642 A5 JP2024540642 A5 JP 2024540642A5
Authority
JP
Japan
Prior art keywords
heterocycloalkyl
alkyl
cycloalkyl
caution
aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024530488A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024540642A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/050777 external-priority patent/WO2023096928A1/en
Publication of JP2024540642A publication Critical patent/JP2024540642A/ja
Publication of JP2024540642A5 publication Critical patent/JP2024540642A5/ja
Pending legal-status Critical Current

Links

JP2024530488A 2021-11-23 2022-11-22 ヘテロ原子含有化合物及びその使用 Pending JP2024540642A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163282614P 2021-11-23 2021-11-23
US63/282,614 2021-11-23
US202263406215P 2022-09-13 2022-09-13
US63/406,215 2022-09-13
PCT/US2022/050777 WO2023096928A1 (en) 2021-11-23 2022-11-22 Hetero-atom containing compounds and uses thereof

Publications (2)

Publication Number Publication Date
JP2024540642A JP2024540642A (ja) 2024-10-31
JP2024540642A5 true JP2024540642A5 (enExample) 2025-12-01

Family

ID=86540280

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024530488A Pending JP2024540642A (ja) 2021-11-23 2022-11-22 ヘテロ原子含有化合物及びその使用

Country Status (13)

Country Link
US (1) US20240398828A1 (enExample)
EP (1) EP4436967A4 (enExample)
JP (1) JP2024540642A (enExample)
KR (1) KR20240126446A (enExample)
AU (1) AU2022397239A1 (enExample)
CA (1) CA3238771A1 (enExample)
CL (1) CL2024001543A1 (enExample)
CO (1) CO2024007220A2 (enExample)
EC (1) ECSP24047821A (enExample)
IL (1) IL313028A (enExample)
MX (1) MX2024006243A (enExample)
PE (2) PE20251600A1 (enExample)
WO (1) WO2023096928A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3238771A1 (en) * 2021-11-23 2023-06-01 Liansheng Li Hetero-atom containing compounds and uses thereof
WO2024243441A1 (en) * 2023-05-24 2024-11-28 Kumquat Biosciences Inc. Heterocyclic compounds and uses thereof
TW202519514A (zh) 2023-07-14 2025-05-16 天主教魯汶大學 新穎化合物(一)
CN119707953B (zh) * 2024-04-19 2026-07-31 中国药科大学 噻二唑烷酮衍生物及其制备方法和应用
CN119707952B (zh) * 2024-04-19 2026-05-26 中国药科大学 具有ptpn2/ptpn1抑制活性的噻二唑烷酮衍生物及其制备方法和应用
WO2026112353A1 (en) * 2024-11-22 2026-05-28 Kumquat Biosciences Inc. Heterocyclic compounds and uses thereof
WO2026112354A1 (en) * 2024-11-22 2026-05-28 Kumquat Biosciences Inc. Heterocyclic compounds and uses thereof
WO2026112355A1 (en) * 2024-11-22 2026-05-28 Kumquat Biosciences Inc. Heterocyclic compounds and uses thereof
WO2026110102A1 (en) * 2024-11-22 2026-05-28 iTeos Belgium SA Protein tyrosine phosphatase inhibitors and methods of use thereof
WO2026112350A1 (en) * 2024-11-22 2026-05-28 Kumquat Biosciences Inc. Heterocyclic compounds and uses thereof
WO2026133154A1 (en) * 2024-12-18 2026-06-25 Novartis Ag Sodium channel blockers
WO2026132148A1 (en) 2024-12-19 2026-06-25 Katholieke Universiteit Leuven Inhibitors of ptpn2/ptpn1 tyrosine phosphatase
WO2026132149A1 (en) 2024-12-19 2026-06-25 Katholieke Universiteit Leuven Inhibitors of ptpn2 and/or ptpn1
WO2026132150A1 (en) 2024-12-19 2026-06-25 Katholieke Universiteit Leuven Inhibitors of ptpn 2/ ptpn1 tyrosine phosphatase
WO2026132146A1 (en) 2024-12-19 2026-06-25 Katholieke Universiteit Leuven Inhibitors of ptpn 2/ ptpn1 tyrosine phosphatase

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0225986D0 (en) * 2002-11-07 2002-12-11 Astrazeneca Ab Chemical compounds
RU2008127253A (ru) * 2005-12-08 2010-01-20 Новартис АГ (CH) 1,1,3-триоксо-1,2,5-тиадиазолидины и их применение в качестве ингибиторов птфаз
JP2009532379A (ja) * 2006-03-31 2009-09-10 ノバルティス アクチエンゲゼルシャフト PTPaseのチアジアゾリジノン阻害剤
WO2008067527A1 (en) * 2006-12-01 2008-06-05 Novartis Ag Inhibitors of protein tyrosine phosphatase for the treatment of muscle atrophy and related disorders
BRPI0819703A2 (pt) * 2007-11-30 2015-06-16 Novartis Ag Uso de inibidores de proteína tirosina fosfatase e hormônio de crescimento humano, uso de igf1 e um inibidor de proteína tirosina fosfatase e composição de combinação farmacêutica para o tratamento de atrofia muscular e distúrbios relacionados
US9977024B2 (en) * 2012-12-09 2018-05-22 The Scripps Research Institute Targeted covalent probes and inhibitors of proteins containing redox-sensitive cysteines
SG11202108452WA (en) * 2019-02-04 2021-09-29 Ksq Therapeutics Inc Combination gene targets for improved immunotherapy
CA3238771A1 (en) * 2021-11-23 2023-06-01 Liansheng Li Hetero-atom containing compounds and uses thereof

Similar Documents

Publication Publication Date Title
US20240083968A1 (en) Treatment of cancer using chimeric cd3 receptor proteins
US12617849B2 (en) Antigen specific CD19-targeted CAR-T cells
US20200360431A1 (en) Bcma-targeting chimeric antigen receptor, cd19-targeting chimeric antigen receptor, and combination therapies
CA3083949A1 (en) Bcma-targeting chimeric antigen receptor, and uses thereof
JP7118887B2 (ja) 最適化されたレンチウイルス移入ベクターおよびその使用
US20190375815A1 (en) Treatment of cancer using chimeric t cell receptor proteins having multiple specificities
US12065474B2 (en) Chimeric antigen receptors with mutated CD28 costimulatory domains
IL295604A (en) Methods of making chimeric antigen receptor-expressing cells
KR20230058427A (ko) Car 발현 세포의 생체내 생성을 위한 조성물 및 방법
US12037394B2 (en) Compositions and methods for targeting CD33-expressing cancers
JP2018527008A5 (enExample)
JP2020513828A5 (enExample)
JP2023138960A (ja) キメラ抗原受容体を発現する免疫細胞
IL316970A (en) Combination therapies of chimeric antigen receptors and PD-1 inhibitors
JP2017513818A5 (enExample)
CN112040957A (zh) 靶向表达cd99的癌症的组合物和方法
JP2024536840A (ja) Il-2バリアント及びその融合タンパク質
US20190374579A1 (en) Tim3-binding chimeric antigen receptors
US20250313622A1 (en) Chimeric antigen receptor (car) constructs with nk receptor signaling domain
US20190276555A1 (en) Tag-72-binding chimeric antigen receptors
US20250302878A1 (en) Nkg2d expressing car-t cells
WO2024196798A1 (en) Fusion protein and uses thereof
WO2026039641A1 (en) Trp-1 binding antibodies and chimeric antigen receptors for targeting melanoma
US20210177903A1 (en) Car t-cells for the treatment of bone metastatic cancer
WO2023220631A2 (en) Selective k-ras inhibitors for the enhancement of adoptive immunotherapies