JP2024537234A5 - - Google Patents

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Publication number
JP2024537234A5
JP2024537234A5 JP2024521130A JP2024521130A JP2024537234A5 JP 2024537234 A5 JP2024537234 A5 JP 2024537234A5 JP 2024521130 A JP2024521130 A JP 2024521130A JP 2024521130 A JP2024521130 A JP 2024521130A JP 2024537234 A5 JP2024537234 A5 JP 2024537234A5
Authority
JP
Japan
Prior art keywords
seq
amino acid
substitution
tgf
monomer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024521130A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024537234A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/077879 external-priority patent/WO2023064747A1/en
Publication of JP2024537234A publication Critical patent/JP2024537234A/ja
Publication of JP2024537234A5 publication Critical patent/JP2024537234A5/ja
Pending legal-status Critical Current

Links

JP2024521130A 2021-10-11 2022-10-11 操作されたTGF-βモノマーおよび使用法 Pending JP2024537234A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163254249P 2021-10-11 2021-10-11
US63/254,249 2021-10-11
PCT/US2022/077879 WO2023064747A1 (en) 2021-10-11 2022-10-11 Engineered tgf-beta monomers and methods of use

Publications (2)

Publication Number Publication Date
JP2024537234A JP2024537234A (ja) 2024-10-10
JP2024537234A5 true JP2024537234A5 (enExample) 2025-10-10

Family

ID=85988028

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024521130A Pending JP2024537234A (ja) 2021-10-11 2022-10-11 操作されたTGF-βモノマーおよび使用法

Country Status (9)

Country Link
US (1) US20240425559A1 (enExample)
EP (1) EP4416172A4 (enExample)
JP (1) JP2024537234A (enExample)
KR (1) KR20240082356A (enExample)
CN (1) CN118103390A (enExample)
AU (1) AU2022367394B2 (enExample)
CA (1) CA3232809A1 (enExample)
TW (1) TW202330579A (enExample)
WO (1) WO2023064747A1 (enExample)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW517059B (en) * 1994-07-25 2003-01-11 Ciba Geigy Ag New process for the production of biologically active protein
US11091523B2 (en) * 2016-11-18 2021-08-17 University of Pittsburgh—of the Commonwealth System of Higher Education Engineered TGF-β monomers and their use for inhibiting TGF-β signaling
JP2023539195A (ja) * 2020-08-27 2023-09-13 ユニバーシティ オブ ピッツバーグ - オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 組換えトランスフォーミング増殖因子(tgf)-ベータ単量体をコードする腫瘍溶解性ウイルスおよびその使用

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