JP2021522795A5 - - Google Patents

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Publication number
JP2021522795A5
JP2021522795A5 JP2020561780A JP2020561780A JP2021522795A5 JP 2021522795 A5 JP2021522795 A5 JP 2021522795A5 JP 2020561780 A JP2020561780 A JP 2020561780A JP 2020561780 A JP2020561780 A JP 2020561780A JP 2021522795 A5 JP2021522795 A5 JP 2021522795A5
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JP
Japan
Prior art keywords
amino acid
sequence
item
acid sequence
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020561780A
Other languages
English (en)
Japanese (ja)
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JP2021522795A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/030475 external-priority patent/WO2019213446A1/en
Publication of JP2021522795A publication Critical patent/JP2021522795A/ja
Publication of JP2021522795A5 publication Critical patent/JP2021522795A5/ja
Pending legal-status Critical Current

Links

JP2020561780A 2018-05-03 2019-05-02 TGFβ−スーパーファミリーのリガンドの新規バインダーおよびその使用 Pending JP2021522795A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862666548P 2018-05-03 2018-05-03
US62/666,548 2018-05-03
US201862779992P 2018-12-14 2018-12-14
US62/779,992 2018-12-14
PCT/US2019/030475 WO2019213446A1 (en) 2018-05-03 2019-05-02 NOVEL BINDERS OF TGFβ-SUPERFAMILY LIGANDS AND USES THEREOF

Publications (2)

Publication Number Publication Date
JP2021522795A JP2021522795A (ja) 2021-09-02
JP2021522795A5 true JP2021522795A5 (enExample) 2022-05-13

Family

ID=68386156

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020561780A Pending JP2021522795A (ja) 2018-05-03 2019-05-02 TGFβ−スーパーファミリーのリガンドの新規バインダーおよびその使用

Country Status (6)

Country Link
US (2) US12168683B2 (enExample)
EP (1) EP3788067A4 (enExample)
JP (1) JP2021522795A (enExample)
AU (1) AU2019262143A1 (enExample)
CA (1) CA3099325A1 (enExample)
WO (1) WO2019213446A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12103959B2 (en) 2018-05-03 2024-10-01 Acceleron Pharma Inc. Multispecific binders of TGFBeta-superfamily ligands and uses thereof
WO2021092079A1 (en) 2019-11-05 2021-05-14 Acceleron Pharma Inc. Treatments for systemic sclerosis
US20240277807A1 (en) * 2021-06-11 2024-08-22 Acceleron Pharma Inc. Actrii proteins and uses thereof
CA3232382A1 (en) * 2021-09-27 2023-03-30 Zoetis Services Llc Anti- tgf.beta.1,2,3 antibodies and therapeutic uses thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2449753T3 (es) 2007-03-19 2014-03-21 National Research Council Of Canada Proteínas de fusión que comprenden dos dominios de unión tgf-beta
CA3253628A1 (en) 2010-03-05 2025-11-29 The Johns Hopkins University Compositions and methods for targeted immunomodulatory antibodies and fusion proteins
US10195249B2 (en) 2012-11-02 2019-02-05 Celgene Corporation Activin-ActRII antagonists and uses for treating bone and other disorders
HK1225740A1 (zh) 2013-08-22 2017-09-15 Acceleron Pharma Inc. TGF-β受体II型变体及其用途
BR112016014952A2 (pt) 2014-02-10 2017-09-19 Merck Patent Gmbh Inibição direcionada de tgfbeta
JP6631865B2 (ja) 2014-08-11 2020-01-15 日本化薬株式会社 TGFβ阻害機能を持つキメラタンパク質
MA41920B1 (fr) * 2015-04-06 2021-05-31 Acceleron Pharma Inc Protéines de fusion de récepteur type i et type ii à bras unique et leurs utilisations
CA3039573A1 (en) * 2016-10-05 2018-04-12 Acceleron Pharma Inc. Alk4:actriib heteromultimers and uses thereof
AU2017338915B2 (en) * 2016-10-05 2024-11-21 Acceleron Pharma Inc. TGF-beta superfamily type I and type II receptor heteromultimers and uses thereof
CN110036025B (zh) 2016-10-05 2024-03-22 阿塞勒隆制药公司 变体ActRIIB蛋白及其用途

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