JP2023554500A5 - - Google Patents

Info

Publication number
JP2023554500A5
JP2023554500A5 JP2023537572A JP2023537572A JP2023554500A5 JP 2023554500 A5 JP2023554500 A5 JP 2023554500A5 JP 2023537572 A JP2023537572 A JP 2023537572A JP 2023537572 A JP2023537572 A JP 2023537572A JP 2023554500 A5 JP2023554500 A5 JP 2023554500A5
Authority
JP
Japan
Prior art keywords
seq
heavy chain
chain monomer
amino acid
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023537572A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023554500A (ja
JP7778148B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2021/061972 external-priority patent/WO2022130342A1/en
Publication of JP2023554500A publication Critical patent/JP2023554500A/ja
Publication of JP2023554500A5 publication Critical patent/JP2023554500A5/ja
Priority to JP2025197132A priority Critical patent/JP2026041774A/ja
Application granted granted Critical
Publication of JP7778148B2 publication Critical patent/JP7778148B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023537572A 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用 Active JP7778148B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025197132A JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063127408P 2020-12-18 2020-12-18
US63/127,408 2020-12-18
PCT/IB2021/061972 WO2022130342A1 (en) 2020-12-18 2021-12-17 Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025197132A Division JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Publications (3)

Publication Number Publication Date
JP2023554500A JP2023554500A (ja) 2023-12-27
JP2023554500A5 true JP2023554500A5 (enExample) 2025-05-20
JP7778148B2 JP7778148B2 (ja) 2025-12-01

Family

ID=82058983

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2023537540A Pending JP2024500839A (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用
JP2023537572A Active JP7778148B2 (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用
JP2025197132A Pending JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2023537540A Pending JP2024500839A (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025197132A Pending JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Country Status (11)

Country Link
US (3) US20250270332A1 (enExample)
EP (3) EP4263618A4 (enExample)
JP (3) JP2024500839A (enExample)
KR (1) KR20230122077A (enExample)
CN (2) CN116917332A (enExample)
AU (2) AU2021399278A1 (enExample)
CA (2) CA3204321A1 (enExample)
CL (2) CL2023001768A1 (enExample)
IL (2) IL303344A (enExample)
MX (1) MX2023007103A (enExample)
WO (2) WO2022130342A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118271444A (zh) 2017-12-19 2024-07-02 瑟罗泽恩奥普瑞汀公司 Wnt替代分子和其用途
KR20220024460A (ko) * 2019-06-11 2022-03-03 안틀라 테라퓨틱스 아이엔씨. 다가 fzd 및 wnt 결합 분자 및 이의 용도
WO2023250402A2 (en) * 2022-06-22 2023-12-28 Antlera Therapeutics Inc. Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof
CR20240266A (es) * 2021-12-31 2024-11-11 Surrozen Operating Inc Compuesto específico de receptor wnt y método relacionado con este
EP4547713A4 (en) * 2022-06-30 2026-07-08 Univ Chicago CD73 Targeting Polypeptides (NT5E)
WO2024227103A1 (en) * 2023-04-27 2024-10-31 Surrozen Operating, Inc. Molecules modulating wnt signaling pathways and uses thereof
WO2025019458A2 (en) * 2023-07-14 2025-01-23 The Trustees Of Columbia University In The City Of New York Specific blood retinal barrier defect in glaucoma directs new treatments and clinical tests
WO2025168716A1 (en) 2024-02-07 2025-08-14 Eyebiotech Limited Compositions, doses, and methods for treatment of ocular diseases
WO2025176843A1 (en) 2024-02-21 2025-08-28 Ags Therapeutics Sas Microalgae extracellular vesicle based gene therapy vectors (mev-gtvs), their preparation, and uses thereof
US20260070966A1 (en) * 2024-09-06 2026-03-12 Eyebiotech Limited Multivalent fzd4, wnt co-receptor, and vegf receptor molecules and uses thereof
US20260092125A1 (en) * 2024-09-06 2026-04-02 Eyebiotech Limited Multivalent fzd4, wnt co-receptor, and vegf binding molecules and uses thereof

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69129154T2 (de) 1990-12-03 1998-08-20 Genentech, Inc., South San Francisco, Calif. Verfahren zur anreicherung von proteinvarianten mit geänderten bindungseigenschaften
JP2003516755A (ja) 1999-12-15 2003-05-20 ジェネンテック・インコーポレーテッド ショットガン走査、すなわち機能性タンパク質エピトープをマッピングするための組み合わせ方法
EP1513879B1 (en) 2002-06-03 2018-08-22 Genentech, Inc. Synthetic antibody phage libraries
AU2004205631A1 (en) 2003-01-16 2004-08-05 Genentech, Inc. Synthetic antibody phage libraries
US7785903B2 (en) 2004-04-09 2010-08-31 Genentech, Inc. Variable domain library and uses
EP1957531B1 (en) 2005-11-07 2016-04-13 Genentech, Inc. Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
WO2007064919A2 (en) 2005-12-02 2007-06-07 Genentech, Inc. Binding polypeptides with restricted diversity sequences
EP2016101A2 (en) 2006-05-09 2009-01-21 Genentech, Inc. Binding polypeptides with optimized scaffolds
CN100592373C (zh) 2007-05-25 2010-02-24 群康科技(深圳)有限公司 液晶显示面板驱动装置及其驱动方法
EP2331136B1 (en) 2008-09-26 2018-01-10 OncoMed Pharmaceuticals, Inc. Frizzled-binding agents and uses thereof
SG10201601747XA (en) 2012-01-18 2016-04-28 Genentech Inc Anti-LRP5 Antibodies And Methods Of Use
DE102012202081A1 (de) 2012-02-13 2013-08-14 Osram Gmbh Glühfaden für elektrische lampen und elektrische lampe sowie herstellungsverfahren für einen glühfaden
WO2014161037A1 (en) 2013-04-03 2014-10-09 Peter Maccallum Cancer Institute Antibodies against human ryk and uses therefor
US9237411B2 (en) 2013-07-25 2016-01-12 Elwha Llc Systems and methods for providing one or more functionalities to a wearable computing device with directional antenna
AU2014306564B2 (en) 2013-08-14 2019-10-17 Antlera Therapeutics Inc. Antibodies against frizzled proteins and methods of use thereof
US20160208018A1 (en) 2015-01-16 2016-07-21 Juno Therapeutics, Inc. Antibodies and chimeric antigen receptors specific for ror1
WO2017127933A1 (en) 2016-01-29 2017-08-03 The Governing Council Of The University Of Toronto Frizzled protein-binding agents and methods of use thereof
WO2018026942A1 (en) 2016-08-02 2018-02-08 Merrimack Pharmaceuticals, Inc. Heteromeric polypeptides
US11039659B2 (en) 2017-09-07 2021-06-22 Nike, Inc. Sole structure for article of footwear
US20210032352A1 (en) 2018-02-14 2021-02-04 Antera Therapeutics Inc. Multivalent Binding Molecules Activating WNT Signaling and Uses Thereof
AU2019297522B2 (en) * 2018-07-05 2026-04-23 Surrozen Operating, Inc. Multi-specific Wnt surrogate molecules and uses thereof
US10671121B2 (en) 2018-09-14 2020-06-02 Apple Inc. Magnetic layout in electronic devices and accessory devices for electronic devices
KR20220024460A (ko) * 2019-06-11 2022-03-03 안틀라 테라퓨틱스 아이엔씨. 다가 fzd 및 wnt 결합 분자 및 이의 용도

Similar Documents

Publication Publication Date Title
WO2022130342A4 (en) Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof
US12398204B2 (en) Method of treating an ocular condition by administering multispecific antibodies that activates TIE2 and binds a receptor tyrosine kinase agonist
JP2023085476A5 (enExample)
JP6742245B2 (ja) 多重特異性抗体
JP2024534545A5 (enExample)
JP2022512234A5 (enExample)
JP2022551969A5 (enExample)
JP2020196744A5 (enExample)
JP2018537966A5 (enExample)
JP2021533779A5 (enExample)
JP2019533441A5 (enExample)
JP2020531438A5 (ja) Nkg2d、cd16、およびhla−eに結合するタンパク質
JP2023548045A5 (enExample)
JP2017537896A5 (enExample)
JP2019502712A5 (enExample)
JP2021507698A5 (enExample)
IL292780A (en) A new 4-1bbl trimer containing antigen-binding molecules
JP2023511376A5 (enExample)
JP2023532129A5 (enExample)
JP2024537779A5 (enExample)
IL311617A (en) NKG2D, CD16 and BAFF-R binding proteins
JP7657591B2 (ja) 二重特異性抗原結合コンストラクト
JP2025124718A5 (enExample)
JPWO2022102768A5 (enExample)
US20260035463A1 (en) Multispecific antibody and use thereof