JP2023554500A5 - - Google Patents

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Publication number
JP2023554500A5
JP2023554500A5 JP2023537572A JP2023537572A JP2023554500A5 JP 2023554500 A5 JP2023554500 A5 JP 2023554500A5 JP 2023537572 A JP2023537572 A JP 2023537572A JP 2023537572 A JP2023537572 A JP 2023537572A JP 2023554500 A5 JP2023554500 A5 JP 2023554500A5
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JP
Japan
Prior art keywords
seq
heavy chain
chain monomer
amino acid
acid sequence
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Application number
JP2023537572A
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English (en)
Japanese (ja)
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JP2023554500A (ja
JP7778148B2 (ja
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Priority claimed from PCT/IB2021/061972 external-priority patent/WO2022130342A1/en
Publication of JP2023554500A publication Critical patent/JP2023554500A/ja
Publication of JP2023554500A5 publication Critical patent/JP2023554500A5/ja
Priority to JP2025197132A priority Critical patent/JP2026041774A/ja
Application granted granted Critical
Publication of JP7778148B2 publication Critical patent/JP7778148B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2023537572A 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用 Active JP7778148B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025197132A JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063127408P 2020-12-18 2020-12-18
US63/127,408 2020-12-18
PCT/IB2021/061972 WO2022130342A1 (en) 2020-12-18 2021-12-17 Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025197132A Division JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Publications (3)

Publication Number Publication Date
JP2023554500A JP2023554500A (ja) 2023-12-27
JP2023554500A5 true JP2023554500A5 (enExample) 2025-05-20
JP7778148B2 JP7778148B2 (ja) 2025-12-01

Family

ID=82058983

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2023537572A Active JP7778148B2 (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用
JP2023537540A Pending JP2024500839A (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用
JP2025197132A Pending JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023537540A Pending JP2024500839A (ja) 2020-12-18 2021-12-17 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用
JP2025197132A Pending JP2026041774A (ja) 2020-12-18 2025-11-18 四価FZD及びWNTコレセプター(co-receptor)結合抗体分子並びにその使用

Country Status (11)

Country Link
US (3) US20250270332A1 (enExample)
EP (3) EP4263617A4 (enExample)
JP (3) JP7778148B2 (enExample)
KR (1) KR20230122077A (enExample)
CN (2) CN116917332A (enExample)
AU (2) AU2021404080A1 (enExample)
CA (2) CA3204321A1 (enExample)
CL (2) CL2023001768A1 (enExample)
IL (2) IL303342A (enExample)
MX (1) MX2023007103A (enExample)
WO (2) WO2022130341A1 (enExample)

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US11773171B2 (en) 2017-12-19 2023-10-03 Surrozen Operating, Inc. WNT surrogate molecules and uses thereof
JP7377288B2 (ja) * 2019-06-11 2023-11-09 アントレラ セラピューティクス インコーポレイテッド 多価fzdおよびwnt結合分子とその使用
WO2023250402A2 (en) * 2022-06-22 2023-12-28 Antlera Therapeutics Inc. Tetravalent fzd and wnt co-receptor binding antibody molecules and uses thereof
EP4457242A4 (en) * 2021-12-31 2025-12-31 Surrozen Operating Inc SPECIFIC COMPOSITE OF A WNT RECEIVER AND ASSOCIATED METHOD
EP4547713A2 (en) * 2022-06-30 2025-05-07 The University of Chicago Cd73 (nt5e) targeting polypeptides
WO2024227103A1 (en) * 2023-04-27 2024-10-31 Surrozen Operating, Inc. Molecules modulating wnt signaling pathways and uses thereof
WO2025019458A2 (en) * 2023-07-14 2025-01-23 The Trustees Of Columbia University In The City Of New York Specific blood retinal barrier defect in glaucoma directs new treatments and clinical tests
WO2025168716A1 (en) 2024-02-07 2025-08-14 Eyebiotech Limited Compositions, doses, and methods for treatment of ocular diseases
WO2025176843A1 (en) 2024-02-21 2025-08-28 Ags Therapeutics Sas Microalgae extracellular vesicle based gene therapy vectors (mev-gtvs), their preparation, and uses thereof
WO2026055308A1 (en) * 2024-09-06 2026-03-12 Merck Sharp & Dohme Llc Multivalent fzd4, wnt co-receptor, and vegf receptor molecules and uses thereof
US20260092125A1 (en) * 2024-09-06 2026-04-02 Eyebiotech Limited Multivalent fzd4, wnt co-receptor, and vegf binding molecules and uses thereof

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CA2095633C (en) 1990-12-03 2003-02-04 Lisa J. Garrard Enrichment method for variant proteins with altered binding properties
EP1240319A1 (en) 1999-12-15 2002-09-18 Genentech, Inc. Shotgun scanning, a combinatorial method for mapping functional protein epitopes
CA2488441C (en) 2002-06-03 2015-01-27 Genentech, Inc. Synthetic antibody phage libraries
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US7785903B2 (en) 2004-04-09 2010-08-31 Genentech, Inc. Variable domain library and uses
ES2577292T3 (es) 2005-11-07 2016-07-14 Genentech, Inc. Polipéptidos de unión con secuencias hipervariables de VH/VL diversificadas y consenso
EP1973951A2 (en) 2005-12-02 2008-10-01 Genentech, Inc. Binding polypeptides with restricted diversity sequences
TW200812616A (en) 2006-05-09 2008-03-16 Genentech Inc Binding polypeptides with optimized scaffolds
CN100592373C (zh) 2007-05-25 2010-02-24 群康科技(深圳)有限公司 液晶显示面板驱动装置及其驱动方法
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US9862776B2 (en) 2013-04-03 2018-01-09 Peter Maccallum Cancer Institute Antibodies against human RYK and uses therefor
US9237411B2 (en) 2013-07-25 2016-01-12 Elwha Llc Systems and methods for providing one or more functionalities to a wearable computing device with directional antenna
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WO2017127933A1 (en) 2016-01-29 2017-08-03 The Governing Council Of The University Of Toronto Frizzled protein-binding agents and methods of use thereof
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US11039659B2 (en) 2017-09-07 2021-06-22 Nike, Inc. Sole structure for article of footwear
JP7550647B2 (ja) * 2018-02-14 2024-09-20 アントレラ セラピューティクス インコーポレイテッド Wntシグナル伝達を活性化する多価結合分子およびその使用
US20210292422A1 (en) 2018-07-05 2021-09-23 Surrozen, Inc. Multi-specific wnt surrogate molecules and uses thereof
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JP7377288B2 (ja) * 2019-06-11 2023-11-09 アントレラ セラピューティクス インコーポレイテッド 多価fzdおよびwnt結合分子とその使用

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