JP2024537779A5 - - Google Patents

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Publication number
JP2024537779A5
JP2024537779A5 JP2024519378A JP2024519378A JP2024537779A5 JP 2024537779 A5 JP2024537779 A5 JP 2024537779A5 JP 2024519378 A JP2024519378 A JP 2024519378A JP 2024519378 A JP2024519378 A JP 2024519378A JP 2024537779 A5 JP2024537779 A5 JP 2024537779A5
Authority
JP
Japan
Prior art keywords
seq
antigen
amino acid
binding site
acid sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024519378A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024537779A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/077083 external-priority patent/WO2023056252A1/en
Publication of JP2024537779A publication Critical patent/JP2024537779A/ja
Publication of JP2024537779A5 publication Critical patent/JP2024537779A5/ja
Pending legal-status Critical Current

Links

JP2024519378A 2021-09-29 2022-09-27 Nkg2d、cd16及びbaff-rに結合するタンパク質 Pending JP2024537779A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163250160P 2021-09-29 2021-09-29
US63/250,160 2021-09-29
PCT/US2022/077083 WO2023056252A1 (en) 2021-09-29 2022-09-27 Proteins binding nkg2d, cd16 and baff-r

Publications (2)

Publication Number Publication Date
JP2024537779A JP2024537779A (ja) 2024-10-16
JP2024537779A5 true JP2024537779A5 (enExample) 2025-10-07

Family

ID=85780907

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024519378A Pending JP2024537779A (ja) 2021-09-29 2022-09-27 Nkg2d、cd16及びbaff-rに結合するタンパク質

Country Status (15)

Country Link
US (2) US20240270861A1 (enExample)
EP (1) EP4408896A4 (enExample)
JP (1) JP2024537779A (enExample)
KR (1) KR20240087855A (enExample)
CN (1) CN118317978A (enExample)
AR (1) AR127162A1 (enExample)
AU (1) AU2022358500A1 (enExample)
CA (1) CA3233377A1 (enExample)
CL (1) CL2024000922A1 (enExample)
CO (1) CO2024003967A2 (enExample)
IL (1) IL311617A (enExample)
MX (1) MX2024003993A (enExample)
PE (1) PE20241584A1 (enExample)
TW (1) TW202330603A (enExample)
WO (1) WO2023056252A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2020008333A (es) 2018-02-08 2020-09-21 Dragonfly Therapeutics Inc Terapia de combinacion del cancer que incluye proteinas de union multiespecificas que activan a las celulas asesinas naturales.
CA3090244A1 (en) 2018-02-08 2019-08-15 Dragonfly Therapeutics, Inc. Antibody variable domains targeting the nkg2d receptor
CN112119093A (zh) 2018-02-20 2020-12-22 蜻蜓治疗公司 结合cd33、nkg2d和cd16的多特异性结合蛋白和使用方法
CA3108427A1 (en) 2018-08-08 2020-02-13 Dragonfly Therapeutics, Inc. Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use
CN113164570B (zh) 2018-08-08 2024-05-14 蜻蜓疗法股份有限公司 结合nkg2d、cd16和肿瘤相关抗原的蛋白质
EA202091888A1 (ru) 2018-08-08 2020-10-23 Драгонфлай Терапьютикс, Инк. Вариабельные домены антител, нацеленные на рецептор nkg2d
AU2021268340A1 (en) 2020-05-06 2022-12-08 Dragonfly Therapeutics, Inc. Proteins binding NKG2D, CD16 and CLEC12A
EP4301774A4 (en) 2021-03-03 2025-08-13 Dragonfly Therapeutics Inc METHODS OF TREATING CANCER USING MULTI-SPECIFIC BINDING PROTEINS THAT BIND TO NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012076670A2 (en) * 2010-12-10 2012-06-14 Novartis Ag Antibody formulation
PL3151921T3 (pl) * 2014-06-06 2020-02-28 Bristol-Myers Squibb Company Przeciwciała przeciwko receptorowi indukowanego glukokortykoidami czynnika martwicy nowotworu (gitr) i ich zastosowania
TWI717375B (zh) * 2015-07-31 2021-02-01 德商安美基研究(慕尼黑)公司 Cd70及cd3抗體構築體
EP4273258A3 (en) * 2017-02-20 2024-01-17 Dragonfly Therapeutics, Inc. Proteins binding her2, nkg2d and cd16
CA3064567A1 (en) * 2017-05-23 2018-11-29 Dragonfly Therapeutics, Inc. A protein binding nkg2d, cd16 and a tumor-associated antigen
RU2021110369A (ru) * 2017-09-07 2021-06-01 Драгонфлай Терапьютикс, Инк. Белки, связывающие nkg2d, cd16 и опухолеассоциированный антиген
EA202091976A1 (ru) * 2018-02-20 2021-07-06 Драгонфлай Терапьютикс, Инк. Вариабельные домены антител, нацеленные на cd33, и их применение
CA3108427A1 (en) * 2018-08-08 2020-02-13 Dragonfly Therapeutics, Inc. Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use
BR112022007128A2 (pt) * 2019-10-15 2022-07-05 Dragonfly Therapeutics Inc Ligação de proteínas nkg2d, cd16 e flt3
WO2021108661A2 (en) * 2019-11-26 2021-06-03 Novartis Ag Chimeric antigen receptors and uses thereof

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