JP2024533396A5 - - Google Patents

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Publication number
JP2024533396A5
JP2024533396A5 JP2024515444A JP2024515444A JP2024533396A5 JP 2024533396 A5 JP2024533396 A5 JP 2024533396A5 JP 2024515444 A JP2024515444 A JP 2024515444A JP 2024515444 A JP2024515444 A JP 2024515444A JP 2024533396 A5 JP2024533396 A5 JP 2024533396A5
Authority
JP
Japan
Prior art keywords
trna
nucleic acid
recombinant
sequence
genome
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024515444A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024533396A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/076106 external-priority patent/WO2023039468A1/en
Publication of JP2024533396A publication Critical patent/JP2024533396A/ja
Publication of JP2024533396A5 publication Critical patent/JP2024533396A5/ja
Pending legal-status Critical Current

Links

JP2024515444A 2021-09-08 2022-09-08 ウイルスガイドrna送達 Pending JP2024533396A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202163241964P 2021-09-08 2021-09-08
US63/241,964 2021-09-08
PCT/US2022/076106 WO2023039468A1 (en) 2021-09-08 2022-09-08 Viral guide rna delivery

Publications (2)

Publication Number Publication Date
JP2024533396A JP2024533396A (ja) 2024-09-12
JP2024533396A5 true JP2024533396A5 (https=) 2025-09-26

Family

ID=84053434

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024515444A Pending JP2024533396A (ja) 2021-09-08 2022-09-08 ウイルスガイドrna送達

Country Status (8)

Country Link
US (1) US20230270840A1 (https=)
EP (1) EP4399303A1 (https=)
JP (1) JP2024533396A (https=)
KR (1) KR20240141708A (https=)
CN (1) CN118369429A (https=)
AU (1) AU2022343725A1 (https=)
CA (1) CA3230629A1 (https=)
WO (1) WO2023039468A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN121575112B (zh) * 2026-01-28 2026-04-24 中南大学湘雅医院 检测用于结肠癌诊断的tsRNA的试剂和试剂盒的应用

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880635B1 (en) 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
US4921757A (en) 1985-04-26 1990-05-01 Massachusetts Institute Of Technology System for delayed and pulsed release of biologically active substances
US4920016A (en) 1986-12-24 1990-04-24 Linear Technology, Inc. Liposomes with enhanced circulation time
JPH0825869B2 (ja) 1987-02-09 1996-03-13 株式会社ビタミン研究所 抗腫瘍剤包埋リポソ−ム製剤
US4917951A (en) 1987-07-28 1990-04-17 Micro-Pak, Inc. Lipid vesicles formed of surfactants and steroids
US4911928A (en) 1987-03-13 1990-03-27 Micro-Pak, Inc. Paucilamellar lipid vesicles
US6174666B1 (en) 1992-03-27 2001-01-16 The United States Of America As Represented By The Department Of Health And Human Services Method of eliminating inhibitory/instability regions from mRNA
US7013219B2 (en) 1999-01-12 2006-03-14 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US6534261B1 (en) 1999-01-12 2003-03-18 Sangamo Biosciences, Inc. Regulation of endogenous gene expression in cells using zinc finger proteins
US6453242B1 (en) 1999-01-12 2002-09-17 Sangamo Biosciences, Inc. Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites
US6599692B1 (en) 1999-09-14 2003-07-29 Sangamo Bioscience, Inc. Functional genomics using zinc finger proteins
EP1235914A2 (en) 1999-11-24 2002-09-04 Joseph Rosenecker Polypeptides comprising multimers of nuclear localization signals or of protein transduction domains and their use for transferring molecules into cells
AU776576B2 (en) 1999-12-06 2004-09-16 Sangamo Biosciences, Inc. Methods of using randomized libraries of zinc finger proteins for the identification of gene function
US6689558B2 (en) 2000-02-08 2004-02-10 Sangamo Biosciences, Inc. Cells for drug discovery
MX341084B (es) 2009-11-02 2016-08-05 Univ Washington Composiciones de nucleasas terapéuticas y métodos.
CA2964796C (en) * 2014-10-17 2022-01-11 The Penn State Research Foundation Methods and compositions for multiplex rna guided genome editing and other rna technologies
AU2016321383B2 (en) 2015-09-11 2021-12-23 Wm. Wrigley Jr. Company Synergistic antibacterial effects of magnolia bark extract and L-arginine, N-alpha-lauroyl ethyl ester on salivary bacteria
CN105139759B (zh) 2015-09-18 2017-10-10 京东方科技集团股份有限公司 一种拼接屏
IL310721B2 (en) 2015-10-23 2025-11-01 Harvard College Nucleobase editors and uses thereof
CN110214183A (zh) 2016-08-03 2019-09-06 哈佛大学的校长及成员们 腺苷核碱基编辑器及其用途
GB201706945D0 (en) * 2017-05-02 2017-06-14 Medical Res Council Self-inactivating viral vector
JP2020038883A (ja) 2018-09-03 2020-03-12 株式会社オートネットワーク技術研究所 回路構造体及び回路構造体の製造方法
CN109722437B (zh) * 2018-12-29 2020-01-07 广州百暨基因科技有限公司 一种通用型car-t细胞及其制备方法和用途
WO2021129895A2 (zh) * 2019-12-23 2021-07-01 浙江大学 侵染性植物弹状病毒载体及无转基因植物基因组定点编辑的方法
CA3208612A1 (en) * 2021-02-19 2022-08-25 Beam Therapeutics Inc. Recombinant rabies viruses for gene therapy
US20240182916A1 (en) * 2021-03-26 2024-06-06 North Carolina State University Recombinant viral expression vectors and methods of use

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