JP2024507533A5 - - Google Patents
Info
- Publication number
- JP2024507533A5 JP2024507533A5 JP2023550277A JP2023550277A JP2024507533A5 JP 2024507533 A5 JP2024507533 A5 JP 2024507533A5 JP 2023550277 A JP2023550277 A JP 2023550277A JP 2023550277 A JP2023550277 A JP 2023550277A JP 2024507533 A5 JP2024507533 A5 JP 2024507533A5
- Authority
- JP
- Japan
- Prior art keywords
- rabies virus
- recombinant
- approximately
- functional variant
- genome
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163151542P | 2021-02-19 | 2021-02-19 | |
| US63/151,542 | 2021-02-19 | ||
| US202163241989P | 2021-09-08 | 2021-09-08 | |
| US63/241,989 | 2021-09-08 | ||
| PCT/US2022/017075 WO2022178307A1 (en) | 2021-02-19 | 2022-02-18 | Recombinant rabies viruses for gene therapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024507533A JP2024507533A (ja) | 2024-02-20 |
| JP2024507533A5 true JP2024507533A5 (https=) | 2025-02-26 |
Family
ID=80953580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023550277A Pending JP2024507533A (ja) | 2021-02-19 | 2022-02-18 | 遺伝子治療のための組み換え狂犬病ウイルス |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220290164A1 (https=) |
| EP (1) | EP4263825A1 (https=) |
| JP (1) | JP2024507533A (https=) |
| KR (1) | KR20230158476A (https=) |
| AU (1) | AU2022224054A1 (https=) |
| CA (1) | CA3208612A1 (https=) |
| WO (1) | WO2022178307A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020051562A2 (en) | 2018-09-07 | 2020-03-12 | Beam Therapeutics Inc. | Compositions and methods for improving base editing |
| EP3847254A4 (en) | 2018-09-07 | 2022-08-10 | Beam Therapeutics Inc. | COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM |
| AU2020215730A1 (en) | 2019-01-31 | 2021-07-29 | Beam Therapeutics Inc. | Nucleobase editors having reduced non-target deamination and assays for characterizing nucleobase editors |
| CN120174005A (zh) | 2019-02-13 | 2025-06-20 | 比姆医疗股份有限公司 | 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞 |
| EP4034138A4 (en) | 2019-09-27 | 2024-07-31 | Beam Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS |
| CA3196831A1 (en) | 2020-09-25 | 2022-03-31 | Beam Therapeutics Inc. | Fratricide resistant modified immune cells and methods of using the same |
| CA3230629A1 (en) * | 2021-09-08 | 2023-03-16 | Beam Therapeutics Inc. | Viral guide rna delivery |
| WO2024163603A1 (en) * | 2023-02-01 | 2024-08-08 | Beam Therapeutics Inc. | Chimeric pseudotyped recombinant rabies virus |
| WO2025111384A1 (en) * | 2023-11-20 | 2025-05-30 | Beam Therapeutics Inc. | Compositions and methods for altering complement activation |
| CN119033805B (zh) * | 2024-08-12 | 2025-07-22 | 华南农业大学 | 靶向抑制狂犬病病毒G基因和/或L基因的siRNA在制备抑制狂犬病的药物中的应用 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4880635B1 (en) | 1984-08-08 | 1996-07-02 | Liposome Company | Dehydrated liposomes |
| US4921757A (en) | 1985-04-26 | 1990-05-01 | Massachusetts Institute Of Technology | System for delayed and pulsed release of biologically active substances |
| US4920016A (en) | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
| JPH0825869B2 (ja) | 1987-02-09 | 1996-03-13 | 株式会社ビタミン研究所 | 抗腫瘍剤包埋リポソ−ム製剤 |
| US4917951A (en) | 1987-07-28 | 1990-04-17 | Micro-Pak, Inc. | Lipid vesicles formed of surfactants and steroids |
| US4911928A (en) | 1987-03-13 | 1990-03-27 | Micro-Pak, Inc. | Paucilamellar lipid vesicles |
| US6174666B1 (en) | 1992-03-27 | 2001-01-16 | The United States Of America As Represented By The Department Of Health And Human Services | Method of eliminating inhibitory/instability regions from mRNA |
| US6534261B1 (en) | 1999-01-12 | 2003-03-18 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6599692B1 (en) | 1999-09-14 | 2003-07-29 | Sangamo Bioscience, Inc. | Functional genomics using zinc finger proteins |
| US7013219B2 (en) | 1999-01-12 | 2006-03-14 | Sangamo Biosciences, Inc. | Regulation of endogenous gene expression in cells using zinc finger proteins |
| EP1235914A2 (en) | 1999-11-24 | 2002-09-04 | Joseph Rosenecker | Polypeptides comprising multimers of nuclear localization signals or of protein transduction domains and their use for transferring molecules into cells |
| AU776576B2 (en) | 1999-12-06 | 2004-09-16 | Sangamo Biosciences, Inc. | Methods of using randomized libraries of zinc finger proteins for the identification of gene function |
| US6689558B2 (en) | 2000-02-08 | 2004-02-10 | Sangamo Biosciences, Inc. | Cells for drug discovery |
| HUP0500722A2 (hu) * | 2001-07-20 | 2005-11-28 | The University of Georgia Research Foundation, Inc@Á | Attenuált veszettség vírus, a veszettség elleni vakcináláshoz és a központi idegrendszer génterápiájához egy nukleoprotein mutációval a foszforilezés helyén |
| MX341084B (es) | 2009-11-02 | 2016-08-05 | Univ Washington | Composiciones de nucleasas terapéuticas y métodos. |
| EP2585598B1 (en) * | 2010-06-24 | 2015-12-30 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services | Pan-lyssavirus vaccines against rabies |
| US10849975B2 (en) * | 2011-02-03 | 2020-12-01 | Thomas Jefferson University | Multivalent vaccines for rabies virus and filoviruses |
| AU2016321383B2 (en) | 2015-09-11 | 2021-12-23 | Wm. Wrigley Jr. Company | Synergistic antibacterial effects of magnolia bark extract and L-arginine, N-alpha-lauroyl ethyl ester on salivary bacteria |
| CN105139759B (zh) | 2015-09-18 | 2017-10-10 | 京东方科技集团股份有限公司 | 一种拼接屏 |
| IL310721B2 (en) | 2015-10-23 | 2025-11-01 | Harvard College | Nucleobase editors and uses thereof |
| US11155885B2 (en) * | 2016-05-20 | 2021-10-26 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Real-time reverse transcriptase-polymerase chain reaction assay with modified probe for the diagnosis of rabies viruses and other lyssaviruses |
| CN110214183A (zh) | 2016-08-03 | 2019-09-06 | 哈佛大学的校长及成员们 | 腺苷核碱基编辑器及其用途 |
| GB201706945D0 (en) * | 2017-05-02 | 2017-06-14 | Medical Res Council | Self-inactivating viral vector |
| WO2019013258A1 (ja) * | 2017-07-11 | 2019-01-17 | 国立大学法人 東京大学 | 光制御性のウイルスタンパク質、その遺伝子、及びその遺伝子を含むウイルスベクター |
| CN109929839B (zh) * | 2017-12-18 | 2021-02-12 | 华东师范大学 | 拆分型单碱基基因编辑系统及其应用 |
| US11453893B2 (en) * | 2018-08-30 | 2022-09-27 | California Institute Of Technology | RNA-based delivery systems with levels of control |
-
2022
- 2022-02-18 CA CA3208612A patent/CA3208612A1/en active Pending
- 2022-02-18 KR KR1020237029781A patent/KR20230158476A/ko active Pending
- 2022-02-18 WO PCT/US2022/017075 patent/WO2022178307A1/en not_active Ceased
- 2022-02-18 JP JP2023550277A patent/JP2024507533A/ja active Pending
- 2022-02-18 AU AU2022224054A patent/AU2022224054A1/en active Pending
- 2022-02-18 US US17/651,738 patent/US20220290164A1/en active Pending
- 2022-02-18 EP EP22713480.6A patent/EP4263825A1/en active Pending
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