JP2024507533A - 遺伝子治療のための組み換え狂犬病ウイルス - Google Patents

遺伝子治療のための組み換え狂犬病ウイルス Download PDF

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JP2024507533A
JP2024507533A JP2023550277A JP2023550277A JP2024507533A JP 2024507533 A JP2024507533 A JP 2024507533A JP 2023550277 A JP2023550277 A JP 2023550277A JP 2023550277 A JP2023550277 A JP 2023550277A JP 2024507533 A JP2024507533 A JP 2024507533A
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rabies virus
recombinant
genome
gene
functional variant
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JP2024507533A5 (https=
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ラン，フェイ
リン，チーユー
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Beam Therapeutics Inc
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Beam Therapeutics Inc
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JP2023550277A 2021-02-19 2022-02-18 遺伝子治療のための組み換え狂犬病ウイルス Pending JP2024507533A (ja)

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Application Number Priority Date Filing Date Title
US202163151542P 2021-02-19 2021-02-19
US63/151,542 2021-02-19
US202163241989P 2021-09-08 2021-09-08
US63/241,989 2021-09-08
PCT/US2022/017075 WO2022178307A1 (en) 2021-02-19 2022-02-18 Recombinant rabies viruses for gene therapy

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JP2024507533A true JP2024507533A (ja) 2024-02-20
JP2024507533A5 JP2024507533A5 (https=) 2025-02-26

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US (1) US20220290164A1 (https=)
EP (1) EP4263825A1 (https=)
JP (1) JP2024507533A (https=)
KR (1) KR20230158476A (https=)
AU (1) AU2022224054A1 (https=)
CA (1) CA3208612A1 (https=)
WO (1) WO2022178307A1 (https=)

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WO2020051562A2 (en) 2018-09-07 2020-03-12 Beam Therapeutics Inc. Compositions and methods for improving base editing
EP3847254A4 (en) 2018-09-07 2022-08-10 Beam Therapeutics Inc. COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM
AU2020215730A1 (en) 2019-01-31 2021-07-29 Beam Therapeutics Inc. Nucleobase editors having reduced non-target deamination and assays for characterizing nucleobase editors
CN120174005A (zh) 2019-02-13 2025-06-20 比姆医疗股份有限公司 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞
EP4034138A4 (en) 2019-09-27 2024-07-31 Beam Therapeutics, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS
CA3196831A1 (en) 2020-09-25 2022-03-31 Beam Therapeutics Inc. Fratricide resistant modified immune cells and methods of using the same
CA3230629A1 (en) * 2021-09-08 2023-03-16 Beam Therapeutics Inc. Viral guide rna delivery
WO2024163603A1 (en) * 2023-02-01 2024-08-08 Beam Therapeutics Inc. Chimeric pseudotyped recombinant rabies virus
WO2025111384A1 (en) * 2023-11-20 2025-05-30 Beam Therapeutics Inc. Compositions and methods for altering complement activation
CN119033805B (zh) * 2024-08-12 2025-07-22 华南农业大学 靶向抑制狂犬病病毒G基因和/或L基因的siRNA在制备抑制狂犬病的药物中的应用

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