KR20230158476A - 유전자 요법을 위한 재조합 광견병 바이러스 - Google Patents

유전자 요법을 위한 재조합 광견병 바이러스 Download PDF

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KR20230158476A
KR20230158476A KR1020237029781A KR20237029781A KR20230158476A KR 20230158476 A KR20230158476 A KR 20230158476A KR 1020237029781 A KR1020237029781 A KR 1020237029781A KR 20237029781 A KR20237029781 A KR 20237029781A KR 20230158476 A KR20230158476 A KR 20230158476A
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rabies virus
recombinant
genome
gene
functional variant
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Korean (ko)
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페이 란
치에유 린
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빔 테라퓨틱스, 인크.
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KR1020237029781A 2021-02-19 2022-02-18 유전자 요법을 위한 재조합 광견병 바이러스 Pending KR20230158476A (ko)

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Application Number Priority Date Filing Date Title
US202163151542P 2021-02-19 2021-02-19
US63/151,542 2021-02-19
US202163241989P 2021-09-08 2021-09-08
US63/241,989 2021-09-08
PCT/US2022/017075 WO2022178307A1 (en) 2021-02-19 2022-02-18 Recombinant rabies viruses for gene therapy

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US (1) US20220290164A1 (https=)
EP (1) EP4263825A1 (https=)
JP (1) JP2024507533A (https=)
KR (1) KR20230158476A (https=)
AU (1) AU2022224054A1 (https=)
CA (1) CA3208612A1 (https=)
WO (1) WO2022178307A1 (https=)

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EP3847254A4 (en) 2018-09-07 2022-08-10 Beam Therapeutics Inc. COMPOSITIONS AND METHODS FOR DELIVERING A NUCLEOBASE EDITING SYSTEM
AU2020215730A1 (en) 2019-01-31 2021-07-29 Beam Therapeutics Inc. Nucleobase editors having reduced non-target deamination and assays for characterizing nucleobase editors
CN120174005A (zh) 2019-02-13 2025-06-20 比姆医疗股份有限公司 具有用于修饰靶标序列中核碱基的腺苷脱氨酶碱基编辑器的经修饰的免疫细胞
EP4034138A4 (en) 2019-09-27 2024-07-31 Beam Therapeutics, Inc. COMPOSITIONS AND METHODS FOR THE TREATMENT OF LIQUID CANCERS
CA3196831A1 (en) 2020-09-25 2022-03-31 Beam Therapeutics Inc. Fratricide resistant modified immune cells and methods of using the same
CA3230629A1 (en) * 2021-09-08 2023-03-16 Beam Therapeutics Inc. Viral guide rna delivery
WO2024163603A1 (en) * 2023-02-01 2024-08-08 Beam Therapeutics Inc. Chimeric pseudotyped recombinant rabies virus
WO2025111384A1 (en) * 2023-11-20 2025-05-30 Beam Therapeutics Inc. Compositions and methods for altering complement activation
CN119033805B (zh) * 2024-08-12 2025-07-22 华南农业大学 靶向抑制狂犬病病毒G基因和/或L基因的siRNA在制备抑制狂犬病的药物中的应用

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