JP2024529108A5 - - Google Patents

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Publication number
JP2024529108A5
JP2024529108A5 JP2024508332A JP2024508332A JP2024529108A5 JP 2024529108 A5 JP2024529108 A5 JP 2024529108A5 JP 2024508332 A JP2024508332 A JP 2024508332A JP 2024508332 A JP2024508332 A JP 2024508332A JP 2024529108 A5 JP2024529108 A5 JP 2024529108A5
Authority
JP
Japan
Prior art keywords
editing system
gene editing
sequence
gene
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024508332A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024529108A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/040042 external-priority patent/WO2023018858A1/en
Publication of JP2024529108A publication Critical patent/JP2024529108A/ja
Publication of JP2024529108A5 publication Critical patent/JP2024529108A5/ja
Pending legal-status Critical Current

Links

JP2024508332A 2021-08-11 2022-08-11 スタスミン2(stmn2)を標的とするrnaガイドを含む遺伝子編集システム及びその使用 Pending JP2024529108A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163231784P 2021-08-11 2021-08-11
US63/231,784 2021-08-11
US202263322002P 2022-03-21 2022-03-21
US63/322,002 2022-03-21
PCT/US2022/040042 WO2023018858A1 (en) 2021-08-11 2022-08-11 Gene editing systems comprising an rna guide targeting stathmin 2 (stmn2) and uses thereof

Publications (2)

Publication Number Publication Date
JP2024529108A JP2024529108A (ja) 2024-08-01
JP2024529108A5 true JP2024529108A5 (https=) 2025-08-19

Family

ID=83193363

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024508332A Pending JP2024529108A (ja) 2021-08-11 2022-08-11 スタスミン2(stmn2)を標的とするrnaガイドを含む遺伝子編集システム及びその使用

Country Status (10)

Country Link
US (2) US20230203539A1 (https=)
EP (1) EP4384618A1 (https=)
JP (1) JP2024529108A (https=)
KR (1) KR20240052763A (https=)
AU (1) AU2022328401A1 (https=)
CA (1) CA3228487A1 (https=)
CO (1) CO2024002315A2 (https=)
IL (1) IL310616A (https=)
MX (1) MX2024001878A (https=)
WO (1) WO2023018858A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023205844A1 (en) * 2022-04-26 2023-11-02 Peter Maccallum Cancer Institute Nucleic acids and uses thereof
KR20250151430A (ko) * 2023-02-15 2025-10-21 아버 바이오테크놀로지스, 인크. 스타스민 2(stmn2) 전사체에서 비정상적인 스플라이싱을 억제하는 유전자 편집 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019178427A1 (en) 2018-03-14 2019-09-19 Arbor Biotechnologies, Inc. Novel crispr dna targeting enzymes and systems
CA3126918A1 (en) * 2019-01-14 2020-07-23 President And Fellows Of Harvard College Methods and compositions for restoring stmn2 levels
EP3976010A4 (en) * 2019-06-03 2023-08-02 Quralis Corporation Oligonucleotides and methods of use for treating neurological diseases
CN121380024A (zh) 2020-03-31 2026-01-23 阿伯生物技术公司 包含Cas12i2变体多肽的组合物及其用途
CN115851665B (zh) * 2021-05-27 2025-01-24 中国科学院动物研究所 工程化的Cas12i核酸酶及其效应蛋白以及用途

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