JP2024529108A - スタスミン２（ｓｔｍｎ２）を標的とするｒｎａガイドを含む遺伝子編集システム及びその使用 - Google Patents

スタスミン２（ｓｔｍｎ２）を標的とするｒｎａガイドを含む遺伝子編集システム及びその使用 Download PDF

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JP2024529108A
JP2024529108A JP2024508332A JP2024508332A JP2024529108A JP 2024529108 A JP2024529108 A JP 2024529108A JP 2024508332 A JP2024508332 A JP 2024508332A JP 2024508332 A JP2024508332 A JP 2024508332A JP 2024529108 A JP2024529108 A JP 2024529108A
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マリー ディトマソ，ティア
ジェイムズ ギャリティ，アンソニー
マイケル ジャキモ，ノア
ノーマン ウェッセルズ，クイントン
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アーバー バイオテクノロジーズ， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C12N2310/00—Structure or type of the nucleic acid
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JP2024508332A 2021-08-11 2022-08-11 スタスミン２（ｓｔｍｎ２）を標的とするｒｎａガイドを含む遺伝子編集システム及びその使用 Pending JP2024529108A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163231784P 2021-08-11 2021-08-11
US63/231,784 2021-08-11
US202263322002P 2022-03-21 2022-03-21
US63/322,002 2022-03-21
PCT/US2022/040042 WO2023018858A1 (en) 2021-08-11 2022-08-11 Gene editing systems comprising an rna guide targeting stathmin 2 (stmn2) and uses thereof

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JP2024529108A true JP2024529108A (ja) 2024-08-01
JP2024529108A5 JP2024529108A5 (https=) 2025-08-19

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US (2) US20230203539A1 (https=)
EP (1) EP4384618A1 (https=)
JP (1) JP2024529108A (https=)
KR (1) KR20240052763A (https=)
AU (1) AU2022328401A1 (https=)
CA (1) CA3228487A1 (https=)
CO (1) CO2024002315A2 (https=)
IL (1) IL310616A (https=)
MX (1) MX2024001878A (https=)
WO (1) WO2023018858A1 (https=)

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* Cited by examiner, † Cited by third party
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WO2023205844A1 (en) * 2022-04-26 2023-11-02 Peter Maccallum Cancer Institute Nucleic acids and uses thereof
KR20250151430A (ko) * 2023-02-15 2025-10-21 아버 바이오테크놀로지스, 인크. 스타스민 2(stmn2) 전사체에서 비정상적인 스플라이싱을 억제하는 유전자 편집 방법

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019178427A1 (en) 2018-03-14 2019-09-19 Arbor Biotechnologies, Inc. Novel crispr dna targeting enzymes and systems
CA3126918A1 (en) * 2019-01-14 2020-07-23 President And Fellows Of Harvard College Methods and compositions for restoring stmn2 levels
EP3976010A4 (en) * 2019-06-03 2023-08-02 Quralis Corporation Oligonucleotides and methods of use for treating neurological diseases
CN121380024A (zh) 2020-03-31 2026-01-23 阿伯生物技术公司 包含Cas12i2变体多肽的组合物及其用途
CN115851665B (zh) * 2021-05-27 2025-01-24 中国科学院动物研究所 工程化的Cas12i核酸酶及其效应蛋白以及用途

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CA3228487A1 (en) 2023-02-16
CO2024002315A2 (es) 2024-03-07
WO2023018858A1 (en) 2023-02-16
US20250127924A1 (en) 2025-04-24
MX2024001878A (es) 2024-02-29
IL310616A (en) 2024-04-01
US20230203539A1 (en) 2023-06-29
KR20240052763A (ko) 2024-04-23
AU2022328401A1 (en) 2024-02-22
EP4384618A1 (en) 2024-06-19

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