JP2024520691A5 - - Google Patents

Info

Publication number
JP2024520691A5
JP2024520691A5 JP2023574534A JP2023574534A JP2024520691A5 JP 2024520691 A5 JP2024520691 A5 JP 2024520691A5 JP 2023574534 A JP2023574534 A JP 2023574534A JP 2023574534 A JP2023574534 A JP 2023574534A JP 2024520691 A5 JP2024520691 A5 JP 2024520691A5
Authority
JP
Japan
Prior art keywords
sequence
gene editing
editing system
gene
rna guide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023574534A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024520691A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2022/032144 external-priority patent/WO2022256642A2/en
Publication of JP2024520691A publication Critical patent/JP2024520691A/ja
Publication of JP2024520691A5 publication Critical patent/JP2024520691A5/ja
Pending legal-status Critical Current

Links

JP2023574534A 2021-06-04 2022-06-03 ヒドロキシ酸オキシダーゼ１（ｈａｏ１）を標的とするｒｎａガイドを含む遺伝子編集システム及びそれらの使用 Pending JP2024520691A (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US202163197073P 2021-06-04 2021-06-04
US63/197,073 2021-06-04
US202163225046P 2021-07-23 2021-07-23
US63/225,046 2021-07-23
US202163292889P 2021-12-22 2021-12-22
US63/292,889 2021-12-22
US202263300727P 2022-01-19 2022-01-19
US63/300,727 2022-01-19
PCT/US2022/032144 WO2022256642A2 (en) 2021-06-04 2022-06-03 Gene editing systems comprising an rna guide targeting hydroxyacid oxidase 1 (hao1) and uses thereof

Publications (2)

Publication Number Publication Date
JP2024520691A JP2024520691A (ja) 2024-05-24
JP2024520691A5 true JP2024520691A5 (https=) 2025-06-11

Family

ID=82694238

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023574534A Pending JP2024520691A (ja) 2021-06-04 2022-06-03 ヒドロキシ酸オキシダーゼ１（ｈａｏ１）を標的とするｒｎａガイドを含む遺伝子編集システム及びそれらの使用

Country Status (12)

Country Link
US (3) US20230032141A1 (https=)
EP (1) EP4347833A2 (https=)
JP (1) JP2024520691A (https=)
KR (1) KR20240034746A (https=)
AU (1) AU2022283922A1 (https=)
CA (1) CA3222159A1 (https=)
CO (1) CO2023018656A2 (https=)
IL (1) IL308803A (https=)
MX (1) MX2023014406A (https=)
PH (1) PH12023553297A1 (https=)
TW (1) TW202317763A (https=)
WO (1) WO2022256642A2 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4711451A1 (en) * 2023-05-11 2026-03-18 Yoltech Therapeutics Co., Ltd Cas protein, corresponding gene editing system thereof and use thereof
WO2025147604A1 (en) 2024-01-05 2025-07-10 Arbor Biotechnologies, Inc. Methods for treating primary hyperoxaluria via genetic editing of hydroxyacid oxidase 1

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3581654B1 (en) * 2013-12-27 2021-03-31 Dicerna Pharmaceuticals, Inc. Methods and compositions for the specific inhibition of glycolate oxidase (hao1) by double-stranded rna
WO2019178427A1 (en) 2018-03-14 2019-09-19 Arbor Biotechnologies, Inc. Novel crispr dna targeting enzymes and systems
MX2021001070A (es) * 2018-07-31 2021-05-27 Intellia Therapeutics Inc Composiciones y métodos para editar el gen hidroxiácido oxidasa 1 (hao1) para tratar la hiperoxaluria primaria tipo 1 (ph1).
CN121380024A (zh) * 2020-03-31 2026-01-23 阿伯生物技术公司 包含Cas12i2变体多肽的组合物及其用途
WO2021257730A2 (en) * 2020-06-16 2021-12-23 Arbor Biotechnologies, Inc. Cells modified by a cas12i polypeptide
CN113308451B (zh) * 2020-12-07 2023-07-25 中国科学院动物研究所 工程化的Cas效应蛋白及其使用方法

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