JP2024527934A5 - - Google Patents
Info
- Publication number
- JP2024527934A5 JP2024527934A5 JP2024504809A JP2024504809A JP2024527934A5 JP 2024527934 A5 JP2024527934 A5 JP 2024527934A5 JP 2024504809 A JP2024504809 A JP 2024504809A JP 2024504809 A JP2024504809 A JP 2024504809A JP 2024527934 A5 JP2024527934 A5 JP 2024527934A5
- Authority
- JP
- Japan
- Prior art keywords
- approximately
- solvent
- compound
- solution
- reducing agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202163225858P | 2021-07-26 | 2021-07-26 | |
| US63/225,858 | 2021-07-26 | ||
| PCT/US2022/038343 WO2023009521A1 (en) | 2021-07-26 | 2022-07-26 | Methods of manufacturing a bifunctional compound |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2024527934A JP2024527934A (ja) | 2024-07-26 |
| JP2024527934A5 true JP2024527934A5 (https=) | 2025-08-04 |
Family
ID=83508570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024504809A Pending JP2024527934A (ja) | 2021-07-26 | 2022-07-26 | 二官能性化合物を製造する方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US12286419B2 (https=) |
| EP (1) | EP4377296A1 (https=) |
| JP (1) | JP2024527934A (https=) |
| KR (1) | KR20240040769A (https=) |
| CN (1) | CN117715889A (https=) |
| AU (1) | AU2022319702A1 (https=) |
| CA (1) | CA3227425A1 (https=) |
| IL (1) | IL309839A (https=) |
| MX (1) | MX2024001118A (https=) |
| WO (1) | WO2023009521A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112019011200B1 (pt) | 2016-12-01 | 2021-12-28 | Arvinas Operations, Inc | Derivados de tetrahidronaftaleno e tetrahidroisoquinolina como degradadores do receptor de estrogênio |
| KR20220054347A (ko) | 2019-08-26 | 2022-05-02 | 아비나스 오퍼레이션스, 인코포레이티드 | 에스트로겐 수용체 분해제로서의 테트라히드로나프탈렌 유도체로 유방암을 치료하는 방법 |
| CA3227425A1 (en) | 2021-07-26 | 2023-02-02 | Arvinas Operations, Inc. | Methods of manufacturing a bifunctional compound |
| WO2025245032A1 (en) | 2024-05-20 | 2025-11-27 | Arvinas Operations, Inc. | Methods of manufacturing a bifunctional compound |
| WO2026018182A1 (en) | 2024-07-19 | 2026-01-22 | Pfizer Inc. | Process for preparing a cis-1,2-diaryltetralin derivative |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4885363A (en) | 1987-04-24 | 1989-12-05 | E. R. Squibb & Sons, Inc. | 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
| MX174467B (es) | 1986-01-23 | 1994-05-17 | Squibb & Sons Inc | 1,4,7-triscarboximetil-1,4,7,10-tetraazaciclodo decano substituido en 1 y compuestos analogos |
| US5965107A (en) | 1992-03-13 | 1999-10-12 | Diatide, Inc. | Technetium-99m labeled peptides for imaging |
| US5808091A (en) | 1991-10-29 | 1998-09-15 | Bracco International B.V. | Rhenium and technetium complexes containing a hypoxia localizing moiety |
| US5608110A (en) | 1993-06-15 | 1997-03-04 | Bracco International B.V. | Heteroatom-bearing ligands and metal complexes thereof |
| ES2114209T3 (es) | 1993-07-19 | 1998-05-16 | Resolution Pharm Inc | Queladores de radionuclidos de tipo hidrazino que tienen una configuracion n3s. |
| US5574140A (en) | 1993-09-03 | 1996-11-12 | Resolution Pharmaceutical Inc. | Hydrazino-type N2 S2 chelators |
| US5662885A (en) | 1994-07-22 | 1997-09-02 | Resolution Pharmaceuticals Inc. | Peptide derived radionuclide chelators |
| US6093382A (en) | 1998-05-16 | 2000-07-25 | Bracco Research Usa Inc. | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications |
| ES2885769T3 (es) * | 2012-08-09 | 2021-12-15 | Celgene Corp | Una forma sólida de clorhidrato de (s)-3-(4-((4-morpholinometil)bencil)oxi)-1-oxoisoindolin-2-il)piperidina-2,6-diona |
| BR112019011200B1 (pt) | 2016-12-01 | 2021-12-28 | Arvinas Operations, Inc | Derivados de tetrahidronaftaleno e tetrahidroisoquinolina como degradadores do receptor de estrogênio |
| EP4406609A3 (en) | 2017-05-30 | 2024-10-02 | Day One Biopharmaceuticals, Inc. | Method for producing optically active compound |
| EP3412666A1 (en) * | 2017-06-07 | 2018-12-12 | Albany Molecular Research, Inc. | Process and intermediates for the preparation of bcl-2 inhibitors including venetoclax through reductive amination |
| US10717703B2 (en) * | 2017-08-21 | 2020-07-21 | Celgene Corporation | Processes for the preparation of (S)-tert-butyl 4,5-diamino-5-oxopentanoate |
| IL302595A (en) * | 2018-04-13 | 2023-07-01 | Arvinas Operations Inc | Servalon ligands and bifunctional compounds containing them |
| JP7307796B2 (ja) | 2019-09-23 | 2023-07-12 | アキュター バイオテクノロジー インコーポレイテッド | アンドロゲン受容体分解活性を有する新規の置換キノリン－８－カルボニトリル誘導体およびその使用 |
| EP3835298B1 (en) | 2019-12-12 | 2024-06-26 | Accutar Biotechnology Inc. | Novel chroman derivatives having estrogen receptor degradation activity and uses thereof |
| CA3227425A1 (en) | 2021-07-26 | 2023-02-02 | Arvinas Operations, Inc. | Methods of manufacturing a bifunctional compound |
| CN113816927B (zh) | 2021-11-23 | 2022-02-25 | 苏州国匡医药科技有限公司 | 一种arv-471中间体的制备方法 |
| CN117126133A (zh) | 2023-08-14 | 2023-11-28 | 中国海洋大学 | 一种化合物及其用途 |
-
2022
- 2022-07-26 CA CA3227425A patent/CA3227425A1/en active Pending
- 2022-07-26 MX MX2024001118A patent/MX2024001118A/es unknown
- 2022-07-26 CN CN202280052419.4A patent/CN117715889A/zh active Pending
- 2022-07-26 US US17/873,748 patent/US12286419B2/en active Active
- 2022-07-26 WO PCT/US2022/038343 patent/WO2023009521A1/en not_active Ceased
- 2022-07-26 EP EP22783075.9A patent/EP4377296A1/en active Pending
- 2022-07-26 JP JP2024504809A patent/JP2024527934A/ja active Pending
- 2022-07-26 KR KR1020247005878A patent/KR20240040769A/ko active Pending
- 2022-07-26 AU AU2022319702A patent/AU2022319702A1/en active Pending
- 2022-07-26 IL IL309839A patent/IL309839A/en unknown
-
2025
- 2025-03-21 US US19/086,983 patent/US20250326740A1/en active Pending
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