JP2024526890A - 代謝障害関連標的遺伝子ｉｒｎａ組成物およびその使用方法 - Google Patents

代謝障害関連標的遺伝子ｉｒｎａ組成物およびその使用方法 Download PDF

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JP2024526890A
JP2024526890A JP2024503574A JP2024503574A JP2024526890A JP 2024526890 A JP2024526890 A JP 2024526890A JP 2024503574 A JP2024503574 A JP 2024503574A JP 2024503574 A JP2024503574 A JP 2024503574A JP 2024526890 A JP2024526890 A JP 2024526890A
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nucleotides
dsrna agent
dsrna
agent
strand
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エム ディートン，エイミー
ズーバー，ジェフリー
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Alnylam Pharmaceuticals Inc
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JP2024503574A 2021-07-21 2022-07-20 代謝障害関連標的遺伝子ｉｒｎａ組成物およびその使用方法 Pending JP2024526890A (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US202163223995P 2021-07-21 2021-07-21
US63/223,995 2021-07-21
US202163278126P 2021-11-11 2021-11-11
US63/278,126 2021-11-11
US202163285143P 2021-12-02 2021-12-02
US63/285,143 2021-12-02
US202163287578P 2021-12-09 2021-12-09
US63/287,578 2021-12-09
US202263321799P 2022-03-21 2022-03-21
US63/321,799 2022-03-21
US202263323543P 2022-03-25 2022-03-25
US63/323,543 2022-03-25
PCT/US2022/037658 WO2023003922A1 (en) 2021-07-21 2022-07-20 Metabolic disorder-associated target gene irna compositions and methods of use thereof

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JP2024526890A true JP2024526890A (ja) 2024-07-19
JP2024526890A5 JP2024526890A5 (https=) 2025-07-25

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US (1) US20240309370A1 (https=)
EP (1) EP4373937A1 (https=)
JP (1) JP2024526890A (https=)
KR (1) KR20240036041A (https=)
CN (1) CN117716032A (https=)
AU (1) AU2022314619A1 (https=)
CA (1) CA3226887A1 (https=)
CL (1) CL2024000130A1 (https=)
CO (1) CO2024000239A2 (https=)
IL (1) IL309897A (https=)
MX (1) MX2024000981A (https=)
TW (1) TW202421169A (https=)
WO (1) WO2023003922A1 (https=)

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TW202539702A (zh) * 2024-03-08 2025-10-16 大陸商上海拓界生物醫藥科技有限公司 靶向ＩＮＨＢＥ的ＲＮＡｉ劑
WO2025193754A2 (en) * 2024-03-11 2025-09-18 Basecure Therapeutics Llc Compositions and methods for inhibition of expression of inhibin subunit beta e (inhbe) genes
WO2025195381A1 (zh) * 2024-03-21 2025-09-25 成都先衍生物技术有限公司 一种靶向INHBE基因表达的siRNA及其缀合物和用途
WO2025201416A1 (zh) * 2024-03-27 2025-10-02 施能康生物医药（苏州）有限公司 靶向抑制素亚单位βE的核酸及其用途
WO2025223537A1 (zh) * 2024-04-26 2025-10-30 信达生物制药(苏州)有限公司 一种dsRNA、其应用及制备方法
WO2025228327A1 (zh) * 2024-04-28 2025-11-06 上海拓界生物医药科技有限公司 靶向ACVR2A的RNAi剂及其医药用途
WO2025228441A2 (en) * 2024-04-30 2025-11-06 Sanegene Bio Usa Inc. Small interfering rna targeting inhbe and uses thereof
WO2025247212A1 (zh) * 2024-05-27 2025-12-04 大睿生物医药科技(上海)有限公司 调控INHBE表达的dsRNA分子
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